Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Brain changes related to Alzheimer's risk may increase financial vulnerability in seniors

Older adults who are more vulnerable to financial scams may have brain changes linked to a higher risk of Alzheimer's disease, according to a first-of-its-kind study led by researchers at the USC Dornsife College of Letters, Arts and Sciences.

6 Sep 2024

Study finds correlation between light pollution and Alzheimer's Disease

In some places around the globe, the lights never go off. Streetlights, roadway lighting, and illuminated signs can deter crime, make roads safer, and enhance landscaping. Undisrupted light, however, comes with ecological, behavioral, and health consequences.

6 Sep 2024

Trinity scientist secures ERC grants to uncover the secrets of brain disorders and repair

Dr. Michael-John Dolan has won a highly prestigious European Research Council (ERC) Starting Grants to pursue research aimed at uncovering the secrets of brain disorders and repair.

5 Sep 2024

Blood-based biomarkers for early detection of Alzheimer's disease

New research has discovered a unique and promising avenue for diagnosing Alzheimer's disease (AD) earlier – by analysing AD biomarkers in blood – so that the impacts of dementia can be reduced.

5 Sep 2024

Does air pollution drive dementia?

Chronic air pollution exposure is a key factor in dementia development, with pollutants like PM2.5 and NO2 linked to cognitive decline and neurodegeneration.

4 Sep 2024

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Researchers reveal how aging and psychiatric disorders converge at the cellular level in the orbitofrontal cortex, identifying key gene expression changes that could lead to new therapies.

4 Sep 2024

Alzheimer's disease: $14.5 trillion burden on global economy by 2050

Study estimates that Alzheimer's disease and other dementias will cost the global economy $14.5 trillion by 2050, disproportionately impacting high-income countries. Researchers call for urgent global action to mitigate this rising economic burden.

4 Sep 2024

Study shows how troriluzole can target early-stage alterations associated with Alzheimer's

In a recent development in Alzheimer's disease research, Auburn University scientists have studied a new drug, troriluzole, that can prevent brain changes leading to memory loss and cognitive decline in a mouse model of the disease.

3 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

Matcha green tea enhances cognition and sleep in older adults

Regular matcha green tea consumption may improve emotional perception and sleep quality in older adults with cognitive decline, though it shows no significant effect on broader cognitive functions.

2 Sep 2024

Study reveals how neighboring synapses compete for plasticity resources

Nerve cells in the brain receive thousands of synaptic signals via their "antenna", the so-called dendritic branch.

2 Sep 2024

American football head impacts tied to increased brain damage and cognitive decline

Repetitive head impacts in former American football players are linked to increased perivascular space volume, which correlates with cognitive decline and neurodegeneration. The study suggests that the force of head impacts may be more critical than frequency, with potential protective effects from β-blocker use.

1 Sep 2024

Tau protein shows unexpected benefits in mitigating brain damage

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key player implicated in several neurodegenerative conditions including Alzheimer's disease – also plays a positive role in the brain.

30 Aug 2024

Breakthrough in stress detection with advanced cortisol measuring device

Stress takes various shapes in our daily lives, from relentless work demands to the constant rush of the school run.

30 Aug 2024

Environmental and social factors impact brain aging, study shows

Your brain ages at different paces according to social and physical environments in aging and dementia.

29 Aug 2024

NIH awards $15.5 million to expand clinical trials inclusion for nursing home residents

A team led by research scientists from the Indiana University School of Medicine and Regenstrief Institute has received funding expected to total $15.5 million from the National Institutes of Health's National Institute on Aging to establish a national network structure to include more nursing home residents in clinical trials.

29 Aug 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

Study reveals the role of blood clotting in COVID-19

In a study that reshapes what we know about COVID-19 and its most perplexing symptoms, scientists have discovered that the blood coagulation protein fibrin causes the unusual clotting and inflammation that have become hallmarks of the disease, while also suppressing the body's ability to clear the virus.

29 Aug 2024

SGLT-2 inhibitors show potential in preventing dementia in diabetes patients

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes might prevent dementia, providing greater benefits with longer treatment, suggests a large study from Korea published by The BMJ today.

28 Aug 2024

Researchers identify key cellular interactions driving Alzheimer's and aging

An analysis of more than 1.6 million brain cells from older adults has captured the cellular changes that occur in the early stages of Alzheimer's disease, potentially revealing new routes for preventing the most common cause of dementia in older individuals.

28 Aug 2024