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Finger-prick blood test shows promise for detecting Alzheimer’s disease biology

Finger-prick dried blood sampling can accurately measure key Alzheimer’s disease biomarkers, including p-tau217, GFAP, and NfL, showing strong concordance with venous plasma and meaningful associations with CSF pathology. While analytical limitations remain, this minimally invasive approach shows promise as a scalable research and screening tool within biomarker-based diagnostic pathways.

6 Jan 2026

AI-powered optical imaging helps surgeons identify thyroid cancer in real time

Thyroid cancer is the most common endocrine cancer, affecting more people each year as detection rates continue to rise.

6 Jan 2026

Why individual differences hold the key to unlocking psychiatric mysteries

In a revealing Genomic Press Interview published today in Genomic Psychiatry, Dr. Noritaka Ichinohe challenges a foundational assumption that has quietly constrained psychiatric research for decades: the belief that meaningful explanation requires averaging away individual differences.

6 Jan 2026

Using contrast-enhanced ultrasound to distinguish hepatic PEComa from HCC without high-risk factors

Announcing a new article publication for BIO Integration journal. Hepatic perivascular epithelioid cell tumor (PEComa) is a rare tumor with malignant potential that is frequently misdiagnosed as hepatocellular carcinoma (HCC), despite requiring distinct treatment approaches.

6 Jan 2026

Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest University School of Medicine synthesizes emerging evidence that two isoforms of a critical cellular energy sensor play distinct, and sometimes opposing, roles in Alzheimer's disease.

6 Jan 2026

AI language models actually help in digestive disease care

Large language models could transform digestive disorder management, but further RCTs are essential to validate their effectiveness and safety in healthcare.

6 Jan 2026

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly used pediatric anesthetic. Its exposure during brain development has been shown to inhibit neurogenesis and cause cognitive dysfunction in animal models.

5 Jan 2026

Orthopedic encounters could play key role in early detection of intimate partner violence

A study by researchers at Mass General Brigham highlights the opportunity for orthopedic surgeons to play a critical role in identifying patients who have experienced intimate partner violence (IPV).

5 Jan 2026

AI method sharply improves noise removal in brain imaging

Obtaining clearer functional MRI data about the brain and its disorders is possible using artificial intelligence, according to Boston College researchers who reported recently in Nature Methods that they developed an AI-assisted method to remove "noise", or image distortions, caused by movement, heartbeat, and other factors.

5 Jan 2026

New guidelines aim to standardize diagnosis of canine dementia

An international working group of canine cognition experts has released a set of guidelines for veterinarians to use in diagnosing and monitoring canine cognitive dysfunction syndrome (CCDS), or canine dementia.

5 Jan 2026

Irregular collagen in uterine scars linked to placenta accreta development

Placenta accreta spectrum (PAS) used to be a rare pregnancy condition, but it now affects roughly 14,000 pregnancies annually, posing a major cause of maternal death.

2 Jan 2026

Label-free polarized light reveals subtle red blood cell deformations

Red blood cells are essential for oxygen transport and immune function in the human body. When these cells become abnormally shaped, they can indicate serious health conditions, including diabetes, malaria, hereditary blood disorders, and vascular diseases.

1 Jan 2026

Infant screen time linked to slower cognitive processing and teen anxiety

Children exposed to high levels of screen time before age two showed changes in brain development that were linked to slower decision-making and increased anxiety by their teenage years, according to new research by Asst Prof Tan Ai Peng and her team from A*STAR Institute for Human Development and Potential (A*STAR IHDP) and National University of Singapore (NUS) Yong Loo Lin School of Medicine, using data from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort.

30 Dec 2025

Imaging-enhanced knowledge graphs reveal new targets for heart disease treatment

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already known about genes, diseases, treatments, molecular pathways and symptoms in a structured network.

30 Dec 2025

Minimal residual disease monitoring can transform breast cancer care

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

30 Dec 2025

Immune cell energy metabolism shapes the progression of atherosclerosis

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

30 Dec 2025

Scientists capture real-time action of antiviral drugs on herpes

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

30 Dec 2025

Brain imaging reveals how stimulant drugs improve performance in ADHD

Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children.

26 Dec 2025

Pediatric surgeons weigh AI benefits against ethical challenges and practical barriers

Artificial intelligence (AI) is rapidly advancing across modern healthcare, yet its role in pediatric surgery remains limited and ethically complex.

26 Dec 2025

Automated system improves deep learning accuracy in chest radiography analysis

Researchers at Osaka Metropolitan University have discovered a practical way to detect and fix common labeling errors in large radiographic collections. By automatically verifying body-part, projection, and rotation tags, their research improves deep-learning models used for routine clinical tasks and research projects.

24 Dec 2025