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The link between constipation and cognitive decline

Researchers report the worsening of cognition among chronically constipated individuals.

25 Jul 2023

Six new Damon Runyon Clinical Investigators announced for 2023

The Damon Runyon Cancer Research Foundation has named six new Damon Runyon Clinical Investigators.

20 Jul 2023

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

A comparison of the antibacterial properties of Cinnamonum cassia and Eucalyptus globulus to their most abundant bioactives metabolites.

20 Jul 2023

Northwestern Medicine scientists discover new therapeutic target for Parkinson’s disease

Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease.

19 Jul 2023

Gut bacteria may play a role in cognitive decline

Two additional studies define specific gut bacteria that are associated with increased dementia risk, as well as gut bacteria that may be neuroprotective.

19 Jul 2023

Gut health breakthrough: probiotics show promise in managing PCOS in obese adolescents

Study examines the impact of probiotic/symbiotic supplementation in adolescents with obesity and PCOS.

18 Jul 2023

Meta-analysis confirms 17 key metabolites as strong predictors of gout

Researchers summarized the use of metabolomics to detect metabolites in gout patients.

18 Jul 2023

Age and immunity: study highlights challenges and opportunities for vaccine protection

Scientists have evaluated molecular mechanisms responsible for heterogeneous responses to influenza vaccination among older adults.

17 Jul 2023

Understanding the impact of HPV on the vaginal microbiome and its role in cervical cancer

Researchers determine whether cervical cancer risk could be assessed using microflora-derived metabolites in HPV-infected females.

17 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Researchers investigate the relationship between the gut microbiome, physical fitness, and epigenetic aging in physically fit individuals.

14 Jul 2023

NOSTER & Science Microbiome Prize winner illuminates how "silent flagellins" from commensal microbiota evade innate immunity

Sara Clasen is the 2023 winner of the NOSTER & Science Microbiome Prize for her work in illuminating how "silent flagellins" from commensal microbiota evade a host's innate immunity.

6 Jul 2023

New blood test could diagnose bile acid diarrhea

Most people have at some point in their life suffered an intestinal infection or food poisoning forcing them to stay close to the bathroom. It is very uncomfortable. Most of the time, though, it passes quickly.

5 Jul 2023

Reproductive impact of changes in the vaginal microbiome of obese women

Study explores the impact of obesity on vaginal microbiota and reproduction.

5 Jul 2023

New atlas offers a way to identify the deep mechanisms of cancer

An atlas that catalogs gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

29 Jun 2023

The effect of coffee consumption on abdominal aortic calcification among adults

How coffee consumption affects the incidence of abdominal aortic calcification.

23 Jun 2023

Mapping the by-products of bacteria processing amino acids associated with cardiovascular disease

A Cleveland Clinic research team recently published an "atlas" of metabolites associated with cardiovascular disease in the European Heart Journal. The novel findings provide key details about the routes and potential branching paths taken by bacteria and metabolic by-products, metabolites.

23 Jun 2023

Study reveals contrasting effects of sucralose on insulin and glucose control

Sucralose, a commonly used artificial sweetener, has contrasting effects on insulin secretion and glucose homeostasis. While bolus administration of sucralose enhances insulin secretion and decreases glucose levels, long-term consumption exacerbates insulin resistance and glucose intolerance, particularly in combination with a high-fat diet. The study highlights the involvement of the T1R3-ERK1/2 pathway in sucralose-induced insulin resistance in the liver.

22 Jun 2023

Study reveals how metformin interacts with the liver and gut to reduce circulating glucose levels

There are still many enigmas about the mechanism of action of metformin, the most prescribed drug to treat diabetes mellitus, also known as type 2 diabetes.