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Could the COVID-19 vaccination rollout protect against future coronavirus outbreaks?

A new study suggests that the rollout of vaccines against the COVID-19 pandemic may be significant not only in preventing infections by SARS-CoV-2 but other endemic and pandemic-potential coronaviruses (CoVs) as well.

10 Jun 2021

The potential of mRNA vaccines for a wide range of diseases

A new review article published in the journal Briefings in Functional Genomics focuses on the general characteristic features and mechanisms of mRNA vaccines. Further, this review has summarized the current progress of mRNA vaccines that have been developed for wide-ranging diseases, including COVID-19 disease.

8 Jun 2021

MIT researchers develop a molecular assay to detect sub-picomolar levels of the SARS-CoV-2's receptor-binding domain

A team of researchers at MIT has developed a molecular assay to detect sub-picomolar levels of the SARS-CoV-2’s spike protein receptor-binding domain (S-RBD) using computationally validated peptide beacons in a single-step detection through the production of a fluorescence signal.

8 Jun 2021

Wearable sensor shows link between blood pressure and intracranial pressure

Brazilian researchers have simultaneously demonstrated the mechanism linking high blood pressure to elevated intracranial pressure, validated a non-invasive intracranial pressure monitoring method, and proposed a treatment for high blood pressure that does not affect intracranial hypertension.

8 Jun 2021

The great promise of antiviral peptides against SARS-CoV-2

A new study, recently published in the journal Viruses, describes the impressive evidence for the role of antimicrobial peptidse (AMPs) in the treatment of COVID-19.

7 Jun 2021

Comparison of immunological profiles of SARS-CoV-2 variants

Mutations to the spike protein and receptor-binding domain are responsible for these changes in immunogenic profile, and in a paper recently uploaded to the open access journal Antibiotics by Ambrose et al. (May 6th, 2021) these mutations are correlated with various disease parameters by in silico methods, finding that particular features are responsible for the increased infectiousness and lesser disease severity observed in these lineages.

6 Jun 2021

Waters launches new RUO LC-MS test method to advance infectious disease research

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

4 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

New process could reinvigorate the search for natural product drugs to treat cancers, viral infections

Researchers from Carnegie Mellon University's Computational Biology Department in the School of Computer Science have developed a new process that could reinvigorate the search for natural product drugs to treat cancers, viral infections and other ailments.

3 Jun 2021

New study will help design better antibodies for potential treatments

Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright X-ray light to determine how specific types of antibodies can tell the difference between different forms of a cancer-linked molecule.

3 Jun 2021

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

NUS researchers develop a way to automate the production of pharmaceutical small molecules

The discovery and development of new small-molecule compounds for therapeutic use involves a huge investment of time, effort and resources.

1 Jun 2021

SARS-CoV-2 variant B.1.617 may be more transmissible and pathogenic due to spike cleavage

In a new research paper currently available on the bioRxiv* preprint server, a research group from the United Kingdom (UK) provides experimental evidence that B.1.617 lineage of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) – also known as the Indian variant of concern – shows enhanced cleavage of spike glycoprotein by furin, which can enhance its transmissibility and pathogenic traits.

31 May 2021

Chemists use new technique to manufacture pharmaceutical cholesterol from plant-based materials

Chemists at Otto von Guericke University Magdeburg have, in collaboration with colleagues from CordenPharma, succeeded for the first time in manufacturing pharmaceutical cholesterol from plant-based materials using a highly-effective technique.

29 May 2021

Identifying SARS-CoV-2 epitopes targeted by current vaccination could help improve future vaccines

Researchers in the United States have identified antibody-inducing epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals vaccinated against coronavirus disease 2019 (COVID-19) that could be used for future diagnostics, therapeutics, and vaccine design.

28 May 2021

Researchers use genomic sequencing technique to detect presence of various microbes

About 12,000 bacteria and viruses collected in a sampling from public transit systems and hospitals around the world from 2015 to 2017 had never before been identified, according to a study by the International MetaSUB Consortium, a global effort at tracking microbes that is led by Weill Cornell Medicine investigators.

27 May 2021

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

From Waters Corporation 27 May 2021

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

Alzheimer's disease - also called dementia - where memory and cognitive functions gradually decline due to deformation and death of neurons, and Parkinson's disease that causes tremors in hands and arms impeding normal movement are major neurodegenerative diseases.

26 May 2021

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

In recent research by Judith Grau-Expósito et al., scientists identify circulating virus-specific T cell responses during acute SARS-CoV-2 infection with functional, migratory, and apoptotic patterns modulated by viral proteins and associated with clinical outcome.

26 May 2021

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

A new study aims to identify antibody-based biomarkers associated with the humoral immune response that could be a standard CoP candidate for COVID-19. Further, standardization of research methods to measure these biomarkers has also been conducted.

25 May 2021

Peptides News and Research

Could the COVID-19 vaccination rollout protect against future coronavirus outbreaks?

The potential of mRNA vaccines for a wide range of diseases

MIT researchers develop a molecular assay to detect sub-picomolar levels of the SARS-CoV-2's receptor-binding domain

Wearable sensor shows link between blood pressure and intracranial pressure

The great promise of antiviral peptides against SARS-CoV-2

Comparison of immunological profiles of SARS-CoV-2 variants

Waters launches new RUO LC-MS test method to advance infectious disease research

Research opens alternative therapeutic avenues for treatment of chronic pain

New process could reinvigorate the search for natural product drugs to treat cancers, viral infections

New study will help design better antibodies for potential treatments

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

NUS researchers develop a way to automate the production of pharmaceutical small molecules

SARS-CoV-2 variant B.1.617 may be more transmissible and pathogenic due to spike cleavage

Chemists use new technique to manufacture pharmaceutical cholesterol from plant-based materials

Identifying SARS-CoV-2 epitopes targeted by current vaccination could help improve future vaccines

Researchers use genomic sequencing technique to detect presence of various microbes

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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