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Cross-reactive coronavirus antibodies might not be cross-neutralizing

In a recent study posted to Research Square* preprint server, researchers reported that cross-reactive antibodies against coronaviruses (CoVs) might not cross-neutralize all CoVs.

25 Apr 2022

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Researchers explore how the presence of SARS-CoV-2 RNA in feces can be associated with the presentation of GI symptoms.

24 Apr 2022

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

Anti-N antibodies may have lower sensitivity in mRNA-1273-vaccinated individuals who were previously infected with SARS-CoV-2.

24 Apr 2022

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

Researchers compared the efficiency of monovalent and bivalent mRNA vaccines against SARS-CoV-2.

22 Apr 2022

COVID-19 mRNA vaccine protects against ICU admission for 1 year

Researchers investigate the duration of effectiveness of mRNA-based COVID-19 vaccines in preventing ICU admission.

21 Apr 2022

Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats.

21 Apr 2022

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Researchers developed an immunoantiviral, NanoSTING, and demonstrated its broad-spectrum antiviral properties in hamsters and mice.

21 Apr 2022

Study examines vitamin D and COVID-19 media coverage in the U.K.

A new study investigates the relationship between COVID-19 and vitamin D that has been presented in traditional media sources like U.K. newspapers.

20 Apr 2022

Novel saliva immunoassays to detect prior SARS-CoV-2 infection

Six salivary ELISAs were developed to evaluate the immune response to SARS-CoV-2 and estimate rates of past infection.

20 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

A point-of-care COVID-19 test developed by researchers at the University of Illinois Urbana-Champaign can now detect and differentiate the alpha variant of the SARS-CoV-2 virus from earlier strains in saliva samples.

20 Apr 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Researchers identified drugs inhibiting the entry of SARS-CoV-2.

18 Apr 2022

SARS-CoV-2 infection patterns in olfactory epithelium

Researchers assess changes in the respiratory and olfactory epithelium of the nasal mucosa in SARS-CoV-2 infections by the WA1, Delta, and Omicron strains.

18 Apr 2022

New study challenges the conventional view of when diverse life began

Diverse microbial life existed on Earth at least 3.75 billion years ago, suggests a new study led by UCL researchers that challenges the conventional view of when life began.

13 Apr 2022

Impact of COVID-19 infection and vaccination on antibody response

A new study assessed the impact of COVID-19 and vaccination on antibody responses.

13 Apr 2022

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Researchers in Australia have evaluated the vaccine candidature of HexaPro S protein subunit vaccine against SARS-CoV-2.

12 Apr 2022

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Researchers tested whether a subunit vaccine could generate mucosal immunity in mice and prevent SARS-CoV-2 infection and related pathology.

11 Apr 2022

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

In a recent study posted to the bioRxiv* preprint server, researchers developed aminoadamantane nitrates compounds that inhibit the ion channels formed by the envelope (E) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enable targeted drug delivery of nitric oxide (NO)-related group for S-nitrosylation of host angiotensin-converting enzyme 2 (ACE2), which would inhibit ACE2 binding with the viral spike (S) protein and thereby inhibit viral replication in the host.

11 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

micro News and Research

Cross-reactive coronavirus antibodies might not be cross-neutralizing

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

COVID-19 mRNA vaccine protects against ICU admission for 1 year

Dual release microparticle system promotes cranial bone defect healing

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Study examines vitamin D and COVID-19 media coverage in the U.K.

Novel saliva immunoassays to detect prior SARS-CoV-2 infection

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

The brain's reaction to COVID's inflammatory tidal wave

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

SARS-CoV-2 infection patterns in olfactory epithelium

New study challenges the conventional view of when diverse life began

Impact of COVID-19 infection and vaccination on antibody response

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

S-Nitrosylation of ACE2 inhibits binding of SARS-CoV-2 spike protein

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

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