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Illinois Tech receives $2.17 million NIH grant to develop drug treatments for cholera

Illinois Institute of Technology is receiving a four-year grant from the National Institutes of Health to fund research to develop drug treatments for cholera and other multi-drug-resistant strains of disease-causing bacteria.

8 Mar 2022

Study reveals new insights on how immune system cells respond to disease-causing pathogens

In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond to disease-causing bacteria, fungi and viruses such as SARS-CoV-2.

8 Mar 2022

Study identifies new immune checkpoint that may be exploited for cancer treatment

A collaborative study led by the Monash Biomedicine Discovery Institute has discovered a new immune checkpoint that may be exploited for cancer therapy.

8 Mar 2022

Ketogenic diet leads to significant improvements in MS symptoms

Patients with relapsing-remitting multiple sclerosis (MS) who adopted a high-fat, low-carbohydrate ketogenic diet saw significant improvements in their MS – including reductions in neurologic disability, fatigue and depression and heightened overall quality of life, a new study finds.

8 Mar 2022

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A recent study assessed neutrophil extracellular trap formation and antiviral host response in high-risk COVID-19 patients.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

A promising approach for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections.

8 Mar 2022

Intersectional, anterograde transsynaptic targeting system used to reveal two different brain circuits

Osaka Metropolitan University uses new “intersectional, anterograde transsynaptic targeting system” to reveal two different mouse brain circuits: the retina/primary visual cortex to the superior colliculus and the bilateral motor cortex to the dorsal striatum.

8 Mar 2022

SARS-CoV-2 spike protein characteristics responsible for viral evolution in human hosts

Researchers directly compared the pre-fusion spikes of SARS-CoV-2 Alpha and Beta variants with the original Wuhan strain and the D614G-only variant.

8 Mar 2022

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

A new study examined a unique case of extended viral shedding in an immunocompromised patient that produced a series of SARS-CoV-2 immune escape mutations over a seven-month period.

8 Mar 2022

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Researchers developed a vaccine candidate termed Ad26.COV2.S.529, encoding a stabilized Omicron-based S protein resembling ancestral SARS-CoV-2 Wuhan-Hu-1 S protein.

8 Mar 2022

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Researchers developed a highly thermo-tolerant vaccine candidate that elicited high nAb titers in mice against several SARS-CoV-2 variants of concerns.

8 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

A recent study reported that monocytosis during the acute phase of coronavirus disease 2019 could forecast anosognosia in long COVID.

8 Mar 2022

Flow Eighteen38 receives €5 million EUR (c.$5.58 million USD) to expand production and biophysical capabilities

Flow Eighteen38, a protein sciences division created to facilitate and accelerate antibody characterization and protein purification projects, today announced a €5 million EUR (c.$5.58 million USD) investment into its protein production and biophysical characterization capabilities and services from its parent company, FairJourney Biologics S.A. (FJB), leaders in the discovery and optimization of antibodies.

From FairJourney Biologics S.A. 8 Mar 2022

Touch-sensing protein in the gut likely plays a key role in constipation

When we eat food, our gut somehow senses its presence to begin shifting it along our digestive tract, but the question has always been – how?

8 Mar 2022

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Helping to advance Alzheimer’s disease (AD) research, scientists from The Feinstein Institutes for Medical Research have published two studies supporting the connection of tau – a protein in the brain that forms neurofibrillary tangles that are a hallmark of AD and have been linked to chronic traumatic encephalopathy (CTE) from head trauma – with psychosis in AD.

8 Mar 2022

Protein C News and Research

Illinois Tech receives $2.17 million NIH grant to develop drug treatments for cholera

Study reveals new insights on how immune system cells respond to disease-causing pathogens

Study identifies new immune checkpoint that may be exploited for cancer treatment

Ketogenic diet leads to significant improvements in MS symptoms

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A promising approach for COVID-19 prophylaxis

Intersectional, anterograde transsynaptic targeting system used to reveal two different brain circuits

SARS-CoV-2 spike protein characteristics responsible for viral evolution in human hosts

Study explores immune escape mutations caused by prolonged viral shedding in immunocompromised COVID-19 patient

Omicron-based vaccine candidate generated to assess whether immunogenicity could be further improved

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Current and future perspectives of mRNA technology

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Study shows anti-itch and pain relief potential of protein in tick saliva

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

Flow Eighteen38 receives €5 million EUR (c.$5.58 million USD) to expand production and biophysical capabilities

Touch-sensing protein in the gut likely plays a key role in constipation

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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