Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

GPEC receives unrestricted grant of $250,000 to study new treatments for breast cancer

Located at Vancouver General Hospital and a partner of the BC Cancer Agency, the Genetic Pathology Evaluation Centre, led by three prominent pathologists, is a recognized world leader in cancer research in the area of biomarker technology. Today, with an additional unrestricted grant of $250,000 from sanofi-aventis, GPEC is ready to make even more scientific breakthroughs.

9 Dec 2009

Researchers describe how PDNF protein prolongs the life of T. cruzi parasite

The parasite Trypanosoma cruzi (or T. cruzi), which causes Chagas' disease, will go to great lengths to evade death once it has infected human host cells, researchers have discovered. In a study published in the November 17 online issue of Science Signaling, the researchers describe how a protein called parasite-derived neurotrophic factor (PDNF) prolongs the life of the T. cruzi parasite by activating anti-apoptotic (or anti-cell-death) molecules in the host cell. These protective mechanisms help to explain how host cells continue to survive despite being exploited by T. cruzi parasites.

9 Dec 2009

Transgenomic's SURVEYOR Scan K-RAS mutation detection kit launched

Transgenomic, Inc. announced today the launch of its SURVEYOR Scan K-RAS kit, the first in a family of mutation detection kits the company plans to offer featuring its proprietary SURVEYOR Nuclease and WAVE® HS DHPLC platform. SURVEYOR Scan technology is a novel approach to mutation detection that uses a PCR amplification reaction and hybridization to form heteroduplex DNA molecules in samples with K-RAS mutation.

9 Dec 2009

Neoprobe completes Phase 3 Lymphoseek clinical trial on breast cancer patients

Neoprobe Corporation (OTCBB: NEOP), a diversified developer of innovative oncology surgical and diagnostic products, has completed a Phase 3 clinical trial of Lymphoseek® (NEO3-05) with positive results.

9 Dec 2009

New data provide comprehensive review of emerging role of small airways in asthma management

Teva Respiratory, a division of Teva Pharmaceutical Industries Ltd., today announced the publication of four articles in a special supplement of the December issue of the Journal of Allergy and Clinical Immunology (JACI), providing a comprehensive scientific review of the emerging role of the small airways in the understanding and treatment of asthma.

8 Dec 2009

Winner of the 2009 Outstanding Investigator Award for Breast Cancer Research

Calling his work "one of the most important findings in breast cancer and health disparities in the last decade," the American Association for Cancer Research (AACR) has named Charles M. Perou, Ph.D. the 2009 Outstanding Investigator Award for Breast Cancer Research, funded by Susan G. Komen for the Cure-.

8 Dec 2009

H1N1 virus produces pulmonary damage similar to earlier flu pandemics

In fatal cases of 2009 H1N1 influenza, the virus can damage cells throughout the respiratory airway, much like the viruses that caused the 1918 and 1957 influenza pandemics, report researchers from the National Institutes of Health (NIH) and the New York City Office of Chief Medical Examiner.

8 Dec 2009

Social isolation and stress can raise breast cancer risk

Social isolation and related stress could contribute to human breast cancer susceptibility, research from a rat model designed at the University of Chicago to identify environmental mechanisms contributing to cancer risk shows.

8 Dec 2009

Cyntellect and Boston University sign research collaboration agreement

Cyntellect, Inc., a privately-held life sciences company commercializing products to advance life science and stem cell research, biopharmaceutical production, and drug discovery, today announced it has entered into a research collaboration agreement with the Boston University School of Medicine.

8 Dec 2009

New data from Allos Therapeutics' FOLOTYN trial for PTCL

Allos Therapeutics, Inc. today reported a new analysis of data from the Company’s pivotal PROPEL trial of FOLOTYN™ (pralatrexate injection) in patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). This indication is based on overall response rate. Clinical benefit such as improvement in progression free survival or overall survival has not been demonstrated.

7 Dec 2009

Kidneys from donors with renal masses to address the current organ shortage

Surgeons who successfully performed kidney transplants after removing small cancerous and benign masses from the donated organs, have published their results in the December issue of the UK-based urology journal BJUI.

7 Dec 2009

New analyses of data from Allos Therapeutics’ pivotal PROPEL trial of FOLOTYN reported

Allos Therapeutics, Inc. today reported new analyses of data from the Company’s pivotal PROPEL trial of FOLOTYN™ (pralatrexate injection) in patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

7 Dec 2009

Health experts available to discuss health care reform

Edward D. Miller was named chief executive officer of Johns Hopkins Medicine, the 13th dean of The Johns Hopkins University School of Medicine and vice president for medicine of The Johns Hopkins University in January 1997.

5 Dec 2009

Genomic Health to present its Oncotype DX multi-gene expression test studies at the 32nd SABCS

Genomic Health, Inc. today announced that the company will present results from five studies at the 32nd Annual San Antonio Breast Cancer Symposium (SABCS), taking place December 9-13, 2009, at the Henry B. Gonzalez Convention Center.

5 Dec 2009

Comparative study on African monkeys may provide novel targets for AIDS therapy

Two studies published this month in the Journal of Clinical Investigation provide a significant advance in understanding how some species of monkeys such as sooty mangabeys and African green monkeys avoid AIDS when infected with SIV, the simian equivalent of HIV.

5 Dec 2009

Researchers discover two new metabolic pathways

Case Western Reserve University researchers, from the School of Medicine's Department of Nutrition, discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abuse, known as 4-hydroxyacids, are metabolized.

5 Dec 2009

Rituximab drug may reduce long-term complications of type 1 diabetes

New findings by UT Southwestern researchers suggest that a drug already used to treat autoimmune disorders might also help slow the destruction of insulin-producing cells in patients recently diagnosed with insulin-dependent (type 1) diabetes.

4 Dec 2009

PLUS Diagnostics expands its specialty anatomic pathology services

PLUS Diagnostics announced today that it has expanded its specialty anatomic pathology services with the launch of a national hematology/oncology offering. The new service completes the company's expansion from a regional laboratory to a leading national anatomic pathology company offering diagnostic services across a full range of specialties including gastroenterology, urology and now hematology/oncology.

4 Dec 2009

New survey concludes health care reform debate as a cause of stress and annoyance among Americans

A new survey released today from Misericordia University and Braun Research finds that two in five Americans plan to spend less this holiday season as a result of rising health care costs. The survey also concluded that the health care reform debate is a cause of stress and annoyance among the majority of Americans and three in ten say health care costs have led to arguments and tension with friends and family members.

4 Dec 2009

Pfizer announces a $9M cancer research collaboration in British Columbia

Pfizer is entering into a three-year, $9-million research collaboration with the BC Cancer Agency and the Vancouver Prostate Centre, a University of British Columbia (UBC) and Vancouver General Hospital (VGH) Centre of Excellence, to tackle new treatment avenues for breast, ovarian and prostate cancer. This is the single-largest investment by Pfizer into British Columbia's public research sector, and it recognizes the strength and world-class cancer expertise that resides in this province.

4 Dec 2009