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Combating COVID cytokine storm with targeted nucleic acid therapies

Researchers examine current nucleic acid-based treatments against COVID-19 and their methods of action.

6 Mar 2022

CD4 T-cell immunity active six months into COVID-19 convalescence

A new paper explores the presence of CD4 T-cell-mediated adaptive immunity against SARS-CoV-2 in late convalescence.

6 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

New technique can upregulate specific genes without permanently altering the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

6 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

Cell-hobbling fibrils found across diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

4 Mar 2022

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk.

4 Mar 2022

T-cell cytokine and fatty acid work together to trigger a type of cell death

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

4 Mar 2022

Melanoma patients do better on immunotherapy than completion lymph node dissection

For years, surgery for patients with stage III melanoma - melanoma that has spread to the lymph nodes - involved removing those lymph nodes along with the primary tumor.

4 Mar 2022

New micro-protein supports cell division and proliferation during nutrient scarcity

Researchers from the University of Eastern Finland and the University of Montreal (Canada) have discovered that a micro-protein, which they named Nrs1, supports cell division and proliferation when nutrients are scarce.

4 Mar 2022

Microneedle treatments could significantly desensitize people with food allergies

Treating peanut allergy with microneedles could significantly improve desensitization by directly targeting the allergen to the skin, providing greater protection from severe allergic reactions for millions of people, a new study suggests.

4 Mar 2022

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

A high-fat diet is not enough to cause short-term fatty liver disease. However, if this diet is combined with the intake of beverages sweetened with liquid fructose, the accumulation of fats in the liver accelerates and hypertriglyceridemia —a cardiovascular risk factor— can appear.

4 Mar 2022

Researchers discover a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers assess the ability of GC-IMS to differentiate between COVID-19 and other respiratory infections, as well as predict disease severity.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

New research helps understand the costs behind popular weight loss diets

When it comes to weight loss, many of us have dabbled in the latest diets. But whether you’re cutting carbs or keeping to keto, new research from the University of South Australia shows that diet trends can cost more than your waistline and leave a hefty hole in your hip pocket.

4 Mar 2022

Effectiveness of mRNA vaccines, antibody treatment reduced by all three omicron subvariants

Only one currently authorized antibody treatment retains its activity against all Omicron subvariants, according to new research by scientists at Columbia University and the University of Hong Kong.

3 Mar 2022

Blood groups play a key role in whether people develop severe COVID-19, study suggests

A new study has analyzed over 3000 proteins to identify which are causally linked to the development of severe COVID-19.

3 Mar 2022

Women's diet may play a role in the development of hypertensive disorder of pregnancy

Diet may play a role in the development of dangerous high blood pressure in late pregnancy among some Hispanic/Latina women, according to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022.

3 Mar 2022

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Use of the drug verapamil to treat Type 1 diabetes continues to show benefits lasting at least two years, researchers report in the journal Nature Communications.

3 Mar 2022

Protein C News and Research

Combating COVID cytokine storm with targeted nucleic acid therapies

CD4 T-cell immunity active six months into COVID-19 convalescence

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

New technique can upregulate specific genes without permanently altering the genome

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Cell-hobbling fibrils found across diverse neurodegenerative diseases

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

T-cell cytokine and fatty acid work together to trigger a type of cell death

Melanoma patients do better on immunotherapy than completion lymph node dissection

New micro-protein supports cell division and proliferation during nutrient scarcity

Microneedle treatments could significantly desensitize people with food allergies

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

Researchers discover a nuclear import mechanism essential for organ growth and development

Gas chromatography-ion mobility spectrometry helps diagnose COVID-19 and predict disease severity

Researchers identify genetic link between lymphatic disorder and stillbirth

New research helps understand the costs behind popular weight loss diets

Effectiveness of mRNA vaccines, antibody treatment reduced by all three omicron subvariants

Blood groups play a key role in whether people develop severe COVID-19, study suggests

Women's diet may play a role in the development of hypertensive disorder of pregnancy

Using oral blood pressure drug to treat Type 1 diabetes shows benefits for at least two years

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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