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Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system.

22 Jul 2021

Largest genetic study identifies new drug targets to treat type 1 diabetes

Scientists have completed the largest and most diverse genetic study of type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.

22 Jul 2021

Finding most promising targets for pan-coronavirus drugs

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.

22 Jul 2021

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

22 Jul 2021

Scientist explore conserved RNA elements as potential targets for anti-SARS-CoV-2 drugs

The study, published in the journal Angewandte Chemie International Edition, identified many small molecules that bind to certain parts of the SARS-CoV-2 genome that are less likely altered by mutations using dedicated substance libraries. The scientists derived key functional units and groups in ligands for effective and safe targeting of SARS-CoV-2 RNA.

22 Jul 2021

Researchers develop a cell culture test to detect substances that harm the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

New method predicts if COVID-19 clinical trials will be completed or suspended

In order to win the battle against COVID-19, studies to develop vaccines, drugs, devices and re-purposed drugs are urgently needed.

21 Jul 2021

Researchers identify immune protein linked to rare neurodegenerative disease

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C.

21 Jul 2021

Oral targeted therapy found to be an effective treatment option for high-risk hairy cell leukemia

The oral targeted therapy drug ibrutinib is an effective treatment option for high-risk hairy cell leukemia, according to a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

21 Jul 2021

Existing drug may be effective in treating COVID-19

A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19.

21 Jul 2021

Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

21 Jul 2021

New technology can pave the way for development of long-acting drugs

The technology, consisting of a designed variant of a natural occurring protein called super albumin, can pave the way for the development of long-acting drugs. This can have major implications for individuals suffering from hemophilia.

21 Jul 2021

Analysis: Necessary or not, covid booster shots are probably on the horizon

The drugmaker Pfizer recently announced that vaccinated people are likely to need a booster shot to be effectively protected against new variants of covid-19 and that the company would apply for Food and Drug Administration emergency use authorization for the shot.

21 Jul 2021

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

A team of researchers at the Institute of Infectious Diseases (IFIK) at the University of Bern and the Institute of Virology and Immunology (IVI) has utilized a unique collection of advanced cell culture models of cells lining the airways from various domesticated and wildlife animals. This way, the team can determine which animals are susceptible to SARS-CoV-2 infection.

20 Jul 2021

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

A study led by D. Ross Camidge, MD, PhD, director of thoracic oncology at the University of Colorado School of Medicine and CU Cancer Center member, has helped to define MET amplification as a rare but potentially actionable driver for non-small cell lung cancer (NSCLC).

20 Jul 2021

APPC survey: Public trust in top U.S. health agencies and Fauci holds steady

With more than two-thirds of American adults vaccinated with at least one dose of an authorized Covid-19 vaccine, the top U.S. health agencies retain the trust of the vast majority of the American public, as does Dr. Anthony Fauci, the public face of U.S. efforts to combat the virus, according to a new survey from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

20 Jul 2021

Study finds dramatic decreases in antibiotic dispensing for children during the pandemic

As children made fewer visits to health facilities and engaged in social distancing and other COVID-19 mitigation measures, a smaller number of them also received prescription drugs, a new study suggests.

20 Jul 2021

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report.

20 Jul 2021

Sen. Wyden: $3.5T budget may have to trim but it can set a path to ‘ambitious goals’

Exactly what American health care will look like if Democrats can pass their $3.5 trillion spending plan is unclear, but the senator negotiating its health-related provisions hopes what emerges will be dramatic: the first complete health care system for older Americans and significantly reduced costs for everyone else.

20 Jul 2021

Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

RedHill Biopharma Ltd., a specialty pharma company that is a leader in the development of novel oral therapies for COVID-19, today announced that all treatment and follow-up has now been completed in the 475-patient global Phase 2/3 study with opaganib (ABC294640) in patients hospitalized with severe COVID-19 pneumonia (NCT04467840). Top-line results are expected in the coming weeks.

20 Jul 2021

Drugs News and Research

Llama ‘nanobodies’ have the potential to outwit human cytomegalovirus

Largest genetic study identifies new drug targets to treat type 1 diabetes

Finding most promising targets for pan-coronavirus drugs

Research provides new insight into uncontrolled inflammation in COVID-19 patients

Scientist explore conserved RNA elements as potential targets for anti-SARS-CoV-2 drugs

Researchers develop a cell culture test to detect substances that harm the placenta and embryo

New method predicts if COVID-19 clinical trials will be completed or suspended

Researchers identify immune protein linked to rare neurodegenerative disease

Oral targeted therapy found to be an effective treatment option for high-risk hairy cell leukemia

Existing drug may be effective in treating COVID-19

Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

New technology can pave the way for development of long-acting drugs

Analysis: Necessary or not, covid booster shots are probably on the horizon

Scientists explore susceptibility of different animals to SARS-CoV-2 infection

MET amplification identified as a potentially actionable driver for non-small cell lung cancer

APPC survey: Public trust in top U.S. health agencies and Fauci holds steady

Study finds dramatic decreases in antibiotic dispensing for children during the pandemic

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

Sen. Wyden: $3.5T budget may have to trim but it can set a path to ‘ambitious goals’

Redhill Biopharma announces completion of Phase 2/3 COVID-19 study of oral opaganib

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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