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Study reveals why people develop life-threatening drug allergies

A research team led by the University of Melbourne and Monash University, Australia, has discovered why people can develop life-threatening allergies after receiving treatment for conditions such as epilepsy and AIDS.

25 May 2012

RUB researchers gain new insights into mechanisms of cardiovascular disease

Malformed desmin proteins aggregate with intact proteins of the same kind, thereby triggering skeletal and cardiac muscle diseases, the desminopathies. This was discovered by researchers from the RUB Heart and Diabetes Center NRW in Bad Oeynhausen led by PD Dr. Hendrik Milting in an interdisciplinary research project with colleagues from the universities in Karlsruhe, Würzburg and Bielefeld. They report in the Journal of Biological Chemistry.

25 May 2012

FDA advisory committee votes in favor of Pfizer's tafamidis meglumine

Pfizer Inc. announced today that the United States Food and Drug Administration's (FDA) Peripheral and Central Nervous System Drugs Advisory Committee voted on Pfizer's clinical data package for tafamidis meglumine.

25 May 2012

UofL receives Helmsley Charitable Trust grant to develop technology for paralyzed people

The University of Louisville has received $6.3 million from the Leona M. and Harry B. Helmsley Charitable Trust to support research in the Department of Neurological Surgery and the Kentucky Spinal Cord Injury Research Center at UofL developing the next generation of technology to help paralyzed people regain movement in their limbs and enhance their quality of life.

25 May 2012

Scientists discover key gene essential for sperm development

A new type of male contraceptive could be created thanks to the discovery of a key gene essential for sperm development.

25 May 2012

Poor cardio-pulmonary function may be strong predictor of survival in women with breast cancer

Women receiving care for breast cancer have significantly impaired cardio-pulmonary function that can persist for years after they have completed treatment, according to a study led by scientists at Duke University Medical Center.

25 May 2012

New MicroNav surgical technique provides greater safety and reduces pain

The revolutionary new MicroNav surgical technique, performed by Dr. Scott Hodges, gives greater safety, less pain, minimal cuts and faster recovery from spine surgery using high-tech 3D scanners and GPS-like instruments. These bold claims are backed by more than 600 surgeries with zero infections and zero revisions, a huge improvement over the high failure rate of "open" surgical techniques and questionable "laser" spine surgery.

24 May 2012

Severe hypersensitivity reactions to anti-HIV drug occur through autoimmune mechanism

Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according to a study published online by the journal AIDS, official journal of the International AIDS Society.

23 May 2012

Exercise can add years to a person's life

A recent study has shown that exercise can add years to a person's life. Still, as we age it can become more tedious and sometimes more difficult to exercise.

23 May 2012

Inhibition of PBEF could be potential therapeutic target for pulmonary hypertension

Inhibition of pre-B Cell Colony-Enhancing Factor (PBEF) could be a potential therapeutic target for pulmonary hypertension (PH), according to a preclinical study in an animal model of PH.

23 May 2012

FSU announces availability of Pacifier Activated Lullaby device

Many premature babies enter the world with a mountain of challenges in front of them. Even after they overcome any life-threatening issues, they face ongoing, and typically unpleasant, medical procedures, long hospital stays and increased chances of chronic health issues throughout their lives.

22 May 2012

HSF-1 protein likely source of chemotherapy-related heart damage in mice

Blocking a protein in the heart that is produced under stressful conditions could be a strategy to prevent cardiac damage that results from chemotherapy, a new study suggests.

22 May 2012

Data from Janssen’s SIMPONI Phase 3 study on ulcerative colitis

New study findings presented today show that subcutaneous induction regimens of the anti-tumor necrosis factor (TNF)-alpha therapy SIMPONI (golimumab) induced clinical response in a majority of patients with moderately to severely active ulcerative colitis (UC) who had previously failed or were intolerant to conventional agents.

22 May 2012

Scientists unravel action mechanism of castor oil

Castor oil is known primarily as an effective laxative; however, it was also used in ancient times with pregnant women to induce labour. Only now have scientists at the Max Planck Institute for Heart and Lung Research succeeded in unravelling the mysteries of the action mechanism. A receptor by the name of EP3 on the cells of the intestine and uterus is apparently responsible. This is activated by an ingredient in the oil.

22 May 2012

More than 16,000 patients visit NYU Langone's new CMC

If the first month at NYU Langone's new Center for Musculoskeletal Care (CMC) is any indication of the growing need for integrated care, the more than 16,000 patients coming to the facility on 38th Street in Manhattan since it opened in April is a true testament.

22 May 2012

Massage therapy effective for knee osteoarthritis, chronic low back pain and fibromyalgia

A growing body of evidence shows massage therapy can be effective for a variety of prevalent health conditions, including the pain of osteoarthritis of the knee, inflammation after exercise, chronic low back pain and fibromyalgia.

21 May 2012

Regenerative medicine researchers explore innovative ways to treat childhood conditions

About 3 percent of the babies born in the United States have a birth defect. Children without a birth defect are also susceptible to injury or disease. At The University of Texas Health Science Center at Houston (UTHealth), regenerative medicine researchers are exploring innovative ways to treat these conditions.

21 May 2012

Salt intake: why is it bad for you?

Many of us are aware that we shouldn’t eat too much salt. To be precise, adults should avoid eating over 6g (or around about a teaspoon of salt) a day.

21 May 2012

Nordic walking enables heart failure patients to exercise more intensely

Nordic walking enables heart failure patients to exercise more intensely than walking without poles.

21 May 2012

Data from Almirall, Forest Labs’ aclidinium studies on COPD to be presented at ATS conference

Forest Laboratories, Inc. and Almirall, S.A. today announced that they will present aclidinium-related data in 1 poster discussion session and 3 poster presentations at the American Thoracic Society (ATS) International Conference scheduled May 18 - 23 in San Francisco, CA.

19 May 2012