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O-GlcNAc sugar is a critical regulator of cells' natural life cycle

The discovery reveals that, when disturbed, this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. The findings are described in the Sept. 23 issue of the Journal of Biological Chemistry, available online now.

20 Sep 2005

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

The study by Bucala and his colleagues in Dublin, Ireland, included experiments in mice that are resistant to developing asthma because they lack the gene, and an examination of a human population in Dublin chosen for their similar ethnic and geographic identity.

20 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

85 percent of embryos transferred during in vitro fertilization fail to become live births

Published in the August issue of Fertility and Sterility, the study reviewed seven years of U.S. statistics from all the fertility clinics that report data on reproductive techniques.

20 Sep 2005

Link between CAPON gene and schizophrenia

We have known for a long time that there is a genetic component to schizophrenia, but nailing down the gene(s) has not been easy.

20 Sep 2005

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Their research, led by Professor Alastair Watson in the University's Faculty of Medicine, could have important implications for the treatment of patients with diseases like Crohn's - an inflammatory bowel disorder that causes severe ulceration in the intestine, leading to pain, bleeding and diarrhoea.

20 Sep 2005

Pocket-size device helps people living with HIV remember their medicine

In a study from Johns Hopkins, a pocket-size device giving electronic-voice reminders to "take your medicine" proves to be a success for people living with HIV whose memory is slightly impaired by the virus.

20 Sep 2005

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Using a recently developed mouse model of breast cancer, a team from the University of Pennsylvania School of Medicine has shown that Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence.

20 Sep 2005

Enhanced imaging techniques could improve medical diagnosis

Chris Wyatt is a Virginia Tech electrical engineer who is attempting to provide the medical community with better, quicker, and more relevant images of the human body. The side effects are not bad either - lower medical costs, new treatments, and earlier disease detection.

19 Sep 2005

High-fat fare increases risk of heart disease for hospital staff and visitors

Nutrition scientists with the Physicians Committee for Responsible Medicine (PCRM) have conducted a nationwide survey to determine if hospital cafeterias and restaurants are meeting the need for low-fat, cholesterol-free foods that can help people maintain a healthy weight and prevent heart disease, diabetes, and some cancers.

19 Sep 2005

Millenium Development Goals fail to include the goal of improving the mental health of the poor

Because the Millenium Development Goals fail to include the goal of improving the mental health of the poor, the world may not reach many of the goals, say researchers in an analysis published by PLoS Medicine.

19 Sep 2005

More than two thirds of meta-analyses available to critical care physicians have major methodological flaws

Research published in Critical Care concludes that the overall quality of meta-analyses in this field is poor, but has improved over time, possibly due to the publication of the Quality of Reporting of Meta-analyses statement (QUOROM) in 1999.

19 Sep 2005

Use of antibiotics for acne may increase risk of upper respiratory tract infection

Individuals treated with antibiotics for acne for more than six weeks were more than twice as likely to develop an upper respiratory tract infection within one year as individuals with acne who were not treated with antibiotics, according to an article in the September issue of Archives of Dermatology.

19 Sep 2005

Injury prevention could save Maryland at least $700 million per year

In 2003, the total estimated cost of injuries in Maryland due to lost productivity and premature mortality was $1.9 billion dollars.

19 Sep 2005

Acute-leukemia sign may signal need for different therapy

A type of chromosome change that was thought to predict a good response to treatment in patients with acute myeloid leukemia (AML) might actually signal the need for a different therapy to achieve the best outcome.

19 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage.

19 Sep 2005

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

The study found that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine.

19 Sep 2005

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.

19 Sep 2005

Making practical markets for vaccines

Two papers published on September 13 in PLoS Medicine raise concerns about whether world leaders are getting good advice on how best to fund the development and delivery of new vaccines.

19 Sep 2005

Medicine News and Research

O-GlcNAc sugar is a critical regulator of cells' natural life cycle

Researchers identify gene prevalent in the population that controls the clinical severity of asthma

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

85 percent of embryos transferred during in vitro fertilization fail to become live births

Link between CAPON gene and schizophrenia

Gaps in the intestinal barrier could be a cause of inflammatory diseases of the gut such as Crohn's Disease

Pocket-size device helps people living with HIV remember their medicine

Snail, a molecule normally important in embryonic development, can promote breast cancer recurrence

Enhanced imaging techniques could improve medical diagnosis

High-fat fare increases risk of heart disease for hospital staff and visitors

Millenium Development Goals fail to include the goal of improving the mental health of the poor

More than two thirds of meta-analyses available to critical care physicians have major methodological flaws

Use of antibiotics for acne may increase risk of upper respiratory tract infection

Injury prevention could save Maryland at least $700 million per year

Acute-leukemia sign may signal need for different therapy

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Making practical markets for vaccines

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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