G Protein News and Research

RSS

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Diabetic nephropathy is one of the most serious complications related to diabetes, often leading to end-stage kidney disease. Purple corn grown in Peru and Chile is a relative of blue corn, which is readily available in the U.S.

20 Sep 2012

Study uncovers why some HIV-positive people take long time to progress to full-blown AIDS

One of the big mysteries of AIDS is why some HIV-positive people take more than a decade to progress to full-blown AIDS, if they progress at all.

20 Sep 2012

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Aerpio Therapeutics, a clinical-stage biopharmaceutical company developing innovative therapies for vascular diseases by targeting the Tie2 pathway, today announced that it has dosed the first patient in a Phase 1b/2a trial of AKB-9778 for the treatment of diabetic macular edema (DME).

20 Sep 2012

Hereditary blood disorder found in South-East Asia, South-West Pacific could offer clues for malaria vaccine

"A team of international scientists has found that a type of hereditary disorder in some communities in South-East Asia and the South-West Pacific protects its sufferers from malaria, a finding that could drive future vaccine design," SciDev.Net reports.

19 Sep 2012

Researchers identify 21 proteins that specifically bind to ataxin-1

Misfolded proteins can cause various neurodegenerative diseases such as spinocerebellar ataxias (SCAs) or Huntington's disease, which are characterized by a progressive loss of neurons in the brain. Researchers of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, together with their colleagues of the Universit- Paris Diderot, Paris, France, have now identified 21 proteins that specifically bind to a protein called ataxin-1.

19 Sep 2012

BGI Tech achieves whole exome sequencing analysis of total degraded DNA from FFPE samples

BGI Tech Solutions Co., Ltd., a subsidiary company of BGI, announced today that they have achieved whole exome sequencing analysis of total degraded DNA as low as 200 ng from formalin fixed paraffin embedded (FFPE) samples.

19 Sep 2012

Power of taxane-based chemotherapy drugs may be potentially underestimated

The power of taxane-based chemotherapy drugs are misunderstood and potentially underestimated, according to researchers at Weill Cornell Medical College in the September 15 issue of the journal Cancer Research.

18 Sep 2012

BACE2 enzyme could represent powerful new tool against Alzheimer's

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme - known as BACE2 - destroys beta-amyloid, a toxic protein fragment that litters the brains of patients who have the disease.

18 Sep 2012

Two abnormalities associated with cystic fibrosis-related diabetes

A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). The findings, which already have sparked a clinical trial, may guide development of new treatments or even help prevent diabetes in patients with CF.

18 Sep 2012

Researchers to probe causes, treatments of toxic reactions in blood plasma

In the largest undertaking of its kind, scientists at four leading U.S. research institutions are embarking upon a five-year National Institutes of Health (NIH)-funded study to make blood transfusions safer and more effective by uncovering the exact causes of hemoglobin toxicity.

18 Sep 2012

New light-based technique demonstrates that toxic proteins build up gradually in blood cells

A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today (17th) in the Journal of Clinical Investigation, the findings shed light on how the protein causes damage in the brain, and could be useful for monitoring the progression of HD, or testing new drugs aimed at suppressing production of the harmful protein.

18 Sep 2012

Researchers obtain first detailed and complete picture of PRC2 protein

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab).

18 Sep 2012

UCSF-led research team targets physiological factors that lead to asthma attack

A new study that identifies ways to reduce the factors that lead to an asthma attack gives hope to asthma sufferers. A UCSF researcher and his colleagues believe they have found a way to help asthma sufferers by impeding the two most significant biological responses that lead to an asthma attack.

18 Sep 2012

Scripps Florida scientist receives two grants to focus on sulfenylation

A scientist from the Florida campus of The Scripps Research Institute has been awarded a pair of grants totaling $2.8 million from the National Institute of General Medical Sciences of the National Institutes of Health, and from TargAnox, a Massachusetts-based biotechnology firm.

18 Sep 2012

Modifying fat intake during pregnancy benefits children regardless of mother's size

If you are overweight and pregnant, your baby isn't destined to a life of obesity after all, according to a new research report published online in The FASEB Journal. In the report, a team of U.S. scientists show that modifying fat intake during pregnancy to a moderate level is enough to benefit the child regardless of the mother's size.

17 Sep 2012

Single HPV protein is required for cervical cancer growths to survive

Human papillomavirus (HPV) has long been implicated in cervical cancer, but details of how it happens have remained a mystery. Now researchers at the University of Wisconsin-Madison have found that a single HPV protein is required for cervical cancer and even pre-cancer growths in the cervix to survive.

17 Sep 2012

Scientists solve co-crystal structure of human antibody that can neutralize influenza viruses

Scientists from The Scripps Research Institute and Sea Lane Biotechnologies have solved the co-crystal structure of a human antibody that can neutralize influenza viruses in a unique way.

17 Sep 2012

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

The rare disorder Wolfram syndrome is caused by mutations in a single gene, but its effects on the body are far reaching. The disease leads to diabetes, hearing and vision loss, nerve cell damage that causes motor difficulties, and early death.

17 Sep 2012

Limited positive effect of Tafamidis in neurological disorders

Tafamidis meglumine was approved in November 2011 for the treatment of transthyretin amyloidosis in adults.

17 Sep 2012

Natural antibiotic to treat tuberculosis

A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown how pyridomycin, a natural antibiotic produced by the bacterium Dactylosporangium fulvum, works.

17 Sep 2012

G Protein News and Research

PCA inhibits multiple pathways involved in development of diabetic nephropathy

Study uncovers why some HIV-positive people take long time to progress to full-blown AIDS

Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema

Hereditary blood disorder found in South-East Asia, South-West Pacific could offer clues for malaria vaccine

Researchers identify 21 proteins that specifically bind to ataxin-1

BGI Tech achieves whole exome sequencing analysis of total degraded DNA from FFPE samples

Power of taxane-based chemotherapy drugs may be potentially underestimated

BACE2 enzyme could represent powerful new tool against Alzheimer's

Two abnormalities associated with cystic fibrosis-related diabetes

Researchers to probe causes, treatments of toxic reactions in blood plasma

New light-based technique demonstrates that toxic proteins build up gradually in blood cells

Researchers obtain first detailed and complete picture of PRC2 protein

UCSF-led research team targets physiological factors that lead to asthma attack

Scripps Florida scientist receives two grants to focus on sulfenylation

Modifying fat intake during pregnancy benefits children regardless of mother's size

Single HPV protein is required for cervical cancer growths to survive

Scientists solve co-crystal structure of human antibody that can neutralize influenza viruses

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

Limited positive effect of Tafamidis in neurological disorders

Natural antibiotic to treat tuberculosis

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News