Aging News and Research

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Researchers discover mechanism that regulates metabolism

The protein complex mTORC1 is a central regulator of cell metabolism. In the active state, it stimulates anabolic processes and increases the production and storage of proteins and lipids. Researchers from the German Leibniz Institute for Age Research in Jena and the Dutch Ageing Institute ERIBA in Groningen discovered a mechanism how mTORC1 regulates metabolism: It controls the expression of a specific variant of the transcriptional regulator C/EBPβ.

29 Jun 2015

Two physician-scientists in search for better Alzheimer's disease treatment

Two of the nation's leading physician-scientists in the search to better understand and treat Alzheimer's disease - William Mobley, MD, PhD, and Michael Rafii, MD, PhD - have been named interim co-directors of the Alzheimer's Disease Cooperative Study (ADCS), a major initiative formed in 1991 as a cooperative agreement between the National Institute on Aging (NIA) and the University of California, San Diego.

27 Jun 2015

ACEP: Supreme Court verdict may not stem the rising tide of visits to emergency departments

The decision today by the Supreme Court will prevent millions of people from losing their health insurance, but does not stem the rising tide of visits to the nation's emergency departments or solve other problems emerging in the post-Affordable Care Act health care system, according to a statement from Dr. Michael Gerardi, president of the American College of Emergency Physicians (ACEP).

27 Jun 2015

UC Riverside psychologist awarded NIA grant to study early influences on cognitive and physical health by middle age

University of California, Riverside psychologist Chandra A. Reynolds has been awarded a $7 million, five-year grant by the National Institute on Aging to study how early childhood influences versus recent influences affect cognitive and physical health by middle age.

27 Jun 2015

Inactivity affects muscular strength in young and older people

New research reveals that it only takes two weeks of not using their legs for young people to lose a third of their muscular strength, leaving them on par with a person who is 40-50 years their senior. The Center for Healthy Aging and the Department of Biomedical Sciences at the University of Copenhagen conducted the research.

27 Jun 2015

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Scientists at Newcastle University have documented for the first time the DNA damage which can occur to skin across the full range of ultraviolet radiation from the sun providing an invaluable tool for sun-protection and the manufacturers of sunscreen.

27 Jun 2015

Different neurobiological pathways lead to expression of Alzheimer's disease

The amyloid cascade hypothesis of Alzheimer's disease (AD) posits that sticky aggregations or plaques of amyloid-beta peptides accumulate over time in the brain, triggering a series of events that ultimately result in the full-blown neurodegenerative disorder. The hypothesis has been a major driver of AD research for more than 20 years.

26 Jun 2015

Unique program enhances sense of purpose and meaning in life for seniors living independently

A unique program combining a life review writing workshop with conversations between seniors and college students enhances the sense of meaning in life for older adults living independently, finds a new study by NYU's Steinhardt School of Culture, Education, and Human Development.

26 Jun 2015

Study reveals differences in the way brain inflammation is expressed in people with Down syndrome, AD

Researchers at the University of Kentucky's Sanders-Brown Center on Aging have completed a study that revealed differences in the way brain inflammation -- considered a key component of AD-- is expressed in different subsets of patients, in particular people with Down syndrome (DS) and AD.

26 Jun 2015

New Internet tool may help analyze genes based on their evolutionary profile

Two major revolutions, one genomic and one in informatics, are completely changing the face of biomedical research. Every day all over the world, millions of genetic sequences -- from disease-related genes to complete genomes of plants, animals, bacteria and viruses -- are resolved, identified and dissected.

26 Jun 2015

Behavioral flexibility is controlled by specific neurons in the brain

Behavioral flexibility -- the ability to change strategy when the rules change -- is controlled by specific neurons in the brain, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have confirmed.

24 Jun 2015

NYU Steinhardt creates Marilyn Moffat Endowed Chair in Physical Therapy to support faculty member

NYU's Steinhardt School of Culture, Education, and Human Development has created the Marilyn Moffat Endowed Chair in Physical Therapy to support a faculty member dedicated to advancing physical therapy through research, teaching, and practice.

24 Jun 2015

Research shows New Zealand blackcurrants are good for keeping us mentally young and agile

Research has shown that New Zealand blackcurrants are good for keeping us mentally young and agile, a finding that could have potential in managing the mental decline associated with aging populations, or helping people with brain disorders such as Parkinson's disease or depression.

24 Jun 2015

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

A digital map of the ageing brain could aid the diagnosis of Alzheimer's disease and other neurodegenerative disorders in older people, a study suggests.

24 Jun 2015

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was evaluated at Hiroshima University, Japan. The relationship between this biomarker, the telomeric 3'-overhang (G-tail) length, and cardiovascular risk in humans is unclear so far.

23 Jun 2015

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

A study at Oregon State University indicates that both a high-fat and a high-sugar diet, compared to a normal diet, cause changes in gut bacteria that appear related to a significant loss of "cognitive flexibility," or the power to adapt and adjust to changing situations.

23 Jun 2015

Scientists explore diabetes-cognitive decline link across cultures

Diabetes is a known risk factor for cognitive decline and dementia, age-related conditions that affect memory and thinking skills. However, little is known about how the diabetes-cognitive decline link compares across cultures.

23 Jun 2015

New study predicts outcomes of CV patients using polypill intervention

A new study published in the journal BMJ Open (May 2015) has demonstrated that the improved treatment adherence achievable using a fixed-dose combination polypill (atorvastatin, ramipril and low-dose aspirin) to prevent recurring myocardial infarction, can avoid up to 15% more fatal and non-fatal CV events, conferring potential savings to healthcare systems.

19 Jun 2015

WSU research provides new strategies for prevention, treatment of obesity

Washington State University scientists have shown that berries, grapes and other fruits convert excess white fat into calorie-burning "beige" fat, providing new strategies for the prevention and treatment of obesity.

19 Jun 2015

UCSF scientists identify characteristics of progenitor cells

University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that generate the entire blood system. The researchers said the discovery raises the possibility that, by manipulating the fates of MPPs or parent stem cells, medical researchers could one day help overcome imbalances and deficiencies that can arise in the blood system due to aging or in patients with specific types of leukemia.

19 Jun 2015

Aging News and Research

Researchers discover mechanism that regulates metabolism

Two physician-scientists in search for better Alzheimer's disease treatment

ACEP: Supreme Court verdict may not stem the rising tide of visits to emergency departments

UC Riverside psychologist awarded NIA grant to study early influences on cognitive and physical health by middle age

Inactivity affects muscular strength in young and older people

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Different neurobiological pathways lead to expression of Alzheimer's disease

Unique program enhances sense of purpose and meaning in life for seniors living independently

Study reveals differences in the way brain inflammation is expressed in people with Down syndrome, AD

New Internet tool may help analyze genes based on their evolutionary profile

Behavioral flexibility is controlled by specific neurons in the brain

NYU Steinhardt creates Marilyn Moffat Endowed Chair in Physical Therapy to support faculty member

Research shows New Zealand blackcurrants are good for keeping us mentally young and agile

Digital map of ageing brain could aid diagnosis of Alzheimer's disease, other neurodegenerative disorders

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

High-fat, high-sugar diet can cause bacterial changes that appear related to loss of 'cognitive flexibility'

Scientists explore diabetes-cognitive decline link across cultures

New study predicts outcomes of CV patients using polypill intervention

WSU research provides new strategies for prevention, treatment of obesity

UCSF scientists identify characteristics of progenitor cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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