Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New method to stimulate immune system may be effective at reducing amyloid burden in Alzheimer?s

Researchers at NYU Langone Medical Center have discovered a novel way to stimulate the innate immune system of mice with Alzheimer's disease (AD) - leading to reduced amyloid deposits and the prevention of Alzheimer's disease related pathology - without causing toxic side effects.

15 Feb 2009

Higher blood sugar levels linked to lower brain function in diabetics, study shows

Results of a recent study conducted by researchers at Wake Forest University Baptist Medical Center and colleagues show that cognitive functioning abilities drop as average blood sugar levels rise in people with type 2 diabetes.

11 Feb 2009

MRI shows brain atrophy pattern that predicts Alzheimer's

Using special MRI methods, researchers have identified a pattern of regional brain atrophy in patients with mild cognitive impairment (MCI) that indicates a greater likelihood of progression to Alzheimer's disease.

10 Feb 2009

Improving brain processing speed helps memory

Mayo Clinic researchers found that healthy, older adults who participated in a computer-based training program to improve the speed and accuracy of brain processing showed twice the improvement in certain aspects of memory, compared to a control group.

10 Feb 2009

Tests may predict driving safety in people with Alzheimer's

Doctors may be able to use certain cognitive tests to help determine whether a person with Alzheimer's disease can safely get behind the wheel.

9 Feb 2009

New efficient technology speeds protein NMR imaging

Solid-state nuclear magnetic resonance, or SSNMR, is a valuable tool to image and analyze the chemical makeup of proteins and other biomolecules.

9 Feb 2009

Eating a Mediterranean diet linked to lower risk of cognitive impairment

Eating a Mediterranean diet appears to be associated with less risk of mild cognitive impairment-a stage between normal aging and dementia-or of transitioning from mild cognitive impairment into Alzheimer's disease, according to a report in the February issue of Archives of Neurology.

9 Feb 2009

Lack of specific gene plays role in autism

It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising.

9 Feb 2009

New understanding of blinding degenerative eye conditions

Though based on mouse studies, the research bolsters the idea that humans suffering from these and other eye conditions may be able to help preserve function by adding antioxidants to their diet, and explains why this would work.

8 Feb 2009

Missing gene plays role in autism

It is estimated that three to six out of every 1,000 children in the United States have autism - and the number of diagnosed cases is rising.

8 Feb 2009

Brain-derived neurotrophic factor protects key brain cells in Alzheimer's models

Memory loss, cognitive impairment, brain cell degeneration and cell death were prevented or reversed in several animal models after treatment with a naturally occurring protein called brain-derived neurotrophic factor (BDNF).

8 Feb 2009

Growth factor protects key brain cells in Alzheimer's models

8 Feb 2009

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

Fasudil could reduce risk of Alzheimer's

A drug used to improve blood flow to the brain also could help improve learning and memory and reduce the risk of Alzheimer's disease, according to a new study released today by investigators at the Translational Genomics Research Institute (TGen) and Arizona State University.

2 Feb 2009

Insulin may slow or prevent damage caused by toxic proteins in Alzheimer's disease

A Northwestern University-led research team reports that insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer's disease.

2 Feb 2009

Genetic change prevents cell death in mouse model of Parkinson's disease

By shifting a normal protective mechanism into overdrive, a University of Wisconsin-Madison scientist has completely shielded mice from a toxic chemical that would otherwise cause Parkinson's disease.

2 Feb 2009

Education may not affect how fast you will lose your memory

While a higher level of education may help lower the risk of Alzheimer's disease, new research shows that once educated people start to become forgetful, a higher level of education does not appear to protect against how fast they will lose their memory.

2 Feb 2009

BioGenes as new designated partner in EU funded dementia project

BioGenes GmbH, a specialist in sophisticated antibody development, has been chosen as a new partner of cNEUPRO. cNEUPRO is a EU funded research project to analyse neurodegenerative diseases and discover novel biomarkers, and so improve early and differential diagnosis of Alzheimer's dementia.

2 Feb 2009

Researchers disrupt biochemical system involved in cancer, degenerative disease

Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases.

2 Feb 2009

Diabetics have a significantly greater risk of dementia

Diabetics have a significantly greater risk of dementia, both Alzheimer's disease - the most common form of dementia - and other dementia, reveals important new data from an ongoing study of twins.

29 Jan 2009