Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study links glymphatic system damage to vascular dementia

A new study from the Keck School of Medicine of USC has tested a biomarker linked to vascular dementia across four separate groups and proposed an explanation for how cognitive impairment arises.

8 Jan 2025

Researchers uncover diverse asthma endotypes in youths using nasal transcriptomics

The study highlights T2-low and T17-high asthma endotypes in minoritized youths, offering insights for precision medicine and improved asthma management.

7 Jan 2025

New biomarkers may offer a more sensitive approach for monitoring kidney health

Drug-induced kidney injury, or nephrotoxicity, is a common complication in clinical medicine that happens when drugs damage the kidneys.

6 Jan 2025

Investigating the impact of CircRNAs on cancer progression and drug resistance

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance.

6 Jan 2025

Y chromosome’s unexpected impact on aging and disease in men

Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of cancer, Alzheimer’s, and cardiovascular diseases, making it a promising biomarker and therapeutic target.

5 Jan 2025

Study reveals potential Alzheimer’s risk in women using hormone replacement therapy

Hormone Replacement Therapy involves giving women synthetic oestrogen to replace depleting hormone levels and thus alleviate menopausal symptoms.

23 Dec 2024

Groundbreaking study sets global handgrip strength benchmarks

Convenient, safe, and non-invasive, "handgrip strength" is a reliable predictor for age-related disease and disability.

20 Dec 2024

New review discusses the expanding horizons of AI in medical sciences

In recent years, artificial intelligence (AI) has grown remarkably, fueled by innovative foundation models (FMs) such as GPT-n series by OpenAI, and derived large language models (LLMs) like Chat generative pre-trained transformer, popularly known as ChatGPT.

20 Dec 2024

Study finds facial shape differences linked to schizophrenia and bipolar disorder

A study published in Psychiatry Research identifies subtle differences in facial shapes that may be linked to the diagnosis of schizophrenia and bipolar disorder.

19 Dec 2024

Chronic gut infection may play role in Alzheimer’s disease progression

Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people.

19 Dec 2024

New blood test could help identify patients at risk for cognitive impairment

To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate "downstream" biological markers – those at the end of a cascade of events.

19 Dec 2024

Free cholesterol in HDL linked to increased cardiovascular disease risk

Houston Methodist researchers have discovered that certain components of so-called "good" cholesterol -- high-density lipoproteins (HDL) – may be associated with an increased prevalence of cardiovascular disease.

19 Dec 2024

Study finds no impact of water fluoridation on cognitive development

A University of Queensland study has found no link between exposure to water fluoridation as a young child and negative cognitive development.

19 Dec 2024

Light and moderate wine consumption linked to lower risk of cardiovascular complications

Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study led by researchers from the University of Barcelona, the Hospital Clínic and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS), the Physiopathology of Obesity and Nutrition Networking Biomedical Research Centre (CIBEROBN) and the University of Navarra (UNAV).

19 Dec 2024

New molecular imaging agent can accurately identify crucial cancer biomarker

A new molecular imaging agent can accurately identify a crucial biomarker found among many different types of cancer.

18 Dec 2024

New diagnostic test offers early detection of osteoarthritis

Diagnosing osteoarthritis often occurs in the late stages when cartilage degradation is severe, making it difficult to distinguish it from other types of arthritis and to determine the best treatment plan.

18 Dec 2024

Neanderthal legacy: The surprising genetics behind human tooth size

A recent study identifies key genetic factors—PITX2 expression and Neanderthal-introgressed HS3ST3A1—that contribute to variations in tooth size among modern human populations, especially highlighting differences across ancestries.

17 Dec 2024

New blood test offers non-invasive way to detect heart transplant rejection

A blood test can show whether a new heart is tolerated by the recipient and not rejected. This has been shown in a thesis from the University of Gothenburg, Sweden.

17 Dec 2024

Breakthrough microchip technology enables multi-disease detection

In a world grappling with a multitude of health threats - ranging from fast-spreading viruses to chronic diseases and drug-resistant bacteria - the need for quick, reliable, and easy-to-use home diagnostic tests has never been greater. Imagine a future where these tests can be done anywhere, by anyone, using a device as small and portable as your smartwatch.

16 Dec 2024

Collaborative project seeks to close diagnostic gap in asthma care

Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day.

16 Dec 2024