Clinical Trial News and Research

RSS

Lubiprostone shows promise in slowing kidney disease progression

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive.

1 Sep 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function.

30 Aug 2025

Constipation drug found to slow renal function decline in CKD patients

Chronic kidney disease (CKD) is a major health issue worldwide. Many patients end up requiring regular dialysis to avoid kidney failure and stay alive.

29 Aug 2025

Sinus surgery proves more effective than antibiotics for chronic rhinosinusitis

Sinus surgery is more effective than antibiotics at treating chronic rhinosinusitis, according to a major clinical trial led by University College London (UCL) along with academics at the University of East Anglia and Guy's and St Thomas' NHS Foundation Trust.

28 Aug 2025

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

28 Aug 2025

Evidence-based calculator to guide hypertension treatment choices

A first-of-its-kind Blood Pressure Treatment Efficacy Calculator built on data from nearly 500 randomized clinical trials in over 100,000 people allows doctors to see by how much different medications are likely to lower blood pressure.

28 Aug 2025

Study brings hope for a more personalized approach to treat ER+ breast cancer

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

28 Aug 2025

Metabolic health plays larger role than weight gain in pregnancy outcomes

Metabolic health before and during pregnancy may have a bigger influence on risks for mother and baby than simply controlling weight gain.

28 Aug 2025

New global consensus offers hope for women with inflammatory bowel disease during pregnancy

For women with inflammatory bowel disease (IBD), pregnancy can be an uncertain time due to limited clinical data about how IBD medications impact pregnancy outcomes and infants who have been exposed to IBD medications in utero.

28 Aug 2025

Omega-3 supplements lower heart rate in male athletes

Six weeks of omega-3 supplementation increases the omega-3 index and lowers heart rate in athletes, yet shows no performance advantage in endurance trials.

28 Aug 2025

Online cognitive behavioral therapy shows promise for treating bulimia nervosa

Bulimia nervosa (BN), or bulimia, is a mental health disorder characterized by binge eating and a fear of gaining weight, which drives people to try and avoid weight gain, usually by compensatory (vomiting etc.).

27 Aug 2025

GLP-1 receptor agonists improve heart failure outcomes and reduce environmental impact

New research has found that the use of GLP-1 receptor agonists, a class of medications commonly prescribed for patients with obesity and diabetes, reduces the environmental footprint of healthcare and clinical outcomes when used to treat heart failure.

27 Aug 2025

Qureight's AI 3D imaging platform to support Calluna Pharma's Phase 2 AURORA study of CAL101 in idiopathic pulmonary fibrosis (IPF)

Qureight, a techbio company advancing the understanding of lung and heart disease through application of its AI-powered imaging and clinical data curation platform, today announced that it has been selected by Calluna Pharma to support its Phase 2 AURORA study.

27 Aug 2025

Mediterranean diet with lifestyle changes lowers diabetes risk by 31%

A Mediterranean-style diet, in combination with reduced caloric intake, moderate physical activity, and professional support for weight loss, may cut the risk of type 2 diabetes (T2D) by 31%, according to a new study co-authored by researchers at Harvard T.H. Chan School of Public Health.

25 Aug 2025

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

Researchers found that acoustic emission dose-an acoustic signal from microbubbles-could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma.

25 Aug 2025

Gut bacteria provide key to identifying colorectal cancer from stool samples

Colorectal cancer is the second leading cause of cancer death worldwide. If detected early, it can be efficiently treated, but the cost and discomfort of colonoscopies - the main diagnostic method currently in use - often result in delayed diagnosis.

25 Aug 2025

Genetic testing of IVF-created embryos could help more women over 35 have a baby sooner

Genetic testing of IVF-created embryos could help more women over 35 have a baby in less time, a clinical trial by researchers from King's College London, King's College Hospital, and King's Fertility has found.

25 Aug 2025

Strategic tips for early-stage animal health companies facing regulatory challenges

Karen Greenwood shares practical advice for early-stage animal health companies navigating FDA CVM processes.

From DSI, a PLG Company 25 Aug 2025

Sugary drinks increase hair loss risk, scientists warn

A systematic review of 17 studies involving 61,332 participants reveals that vitamin D, iron, and certain foods and supplements play critical roles in hair health. Conversely, sugary drinks, alcohol, and excess vitamin A may worsen hair loss and hair quality.

25 Aug 2025

Previous
1
...
53
54
55
56
57
58
59
...
1183
Next

Clinical Trial News and Research

Lubiprostone shows promise in slowing kidney disease progression

Ultra-processed foods affect sperm quality and metabolism even without extra calories

REBOOT trial finds no benefit of beta blockers after uncomplicated heart attacks

Constipation drug found to slow renal function decline in CKD patients

Sinus surgery proves more effective than antibiotics for chronic rhinosinusitis

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Evidence-based calculator to guide hypertension treatment choices

Study brings hope for a more personalized approach to treat ER+ breast cancer

Metabolic health plays larger role than weight gain in pregnancy outcomes

New global consensus offers hope for women with inflammatory bowel disease during pregnancy

Omega-3 supplements lower heart rate in male athletes

Online cognitive behavioral therapy shows promise for treating bulimia nervosa

GLP-1 receptor agonists improve heart failure outcomes and reduce environmental impact

Qureight's AI 3D imaging platform to support Calluna Pharma's Phase 2 AURORA study of CAL101 in idiopathic pulmonary fibrosis (IPF)

Mediterranean diet with lifestyle changes lowers diabetes risk by 31%

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

Gut bacteria provide key to identifying colorectal cancer from stool samples

Genetic testing of IVF-created embryos could help more women over 35 have a baby sooner

Strategic tips for early-stage animal health companies facing regulatory challenges

Sugary drinks increase hair loss risk, scientists warn

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Metabolomics

Improve fermentation and cell culture performance with real-time gas analysis

Scaling patient-derived organoid research

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer