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Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

A new study aimed to explore whether there is a way to induce the production of potent neutralizing antibodies capable of neutralizing all SARS-CoV-2 variants - including Omicron.

7 Jan 2022

Evaluating the response of lung cancer patients to COVID-19 mRNA vaccination

Researchers examine the efficacy of mRNA COVID-19 vaccination in NSCLC patients.

6 Jan 2022

Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Researchers analyzed ACE2-binding inhibition and antibody binding for the SARS-CoV-2 Omicron variants in individuals with varying levels of immunity.

6 Jan 2022

Serological antibody response to SARS-CoV-2 infection at a population level

The scientists in this study used pooled convalescent serum to examine the serologic response in a population at risk of infection.

6 Jan 2022

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

Researchers determine the cross-reactivity of the SARS-CoV-2 spike glycoprotein-induced antibodies before and after a third SARS-CoV-2 vaccine dose.

5 Jan 2022

COVID-19 mRNA vaccines offer protection against Omicron variant in pregnancy

A new study provides insights into the persistence of extra-neutralizing properties of mRNA vaccine-induced antibodies resulting in protection against the Omicron variant of SARS-CoV-2.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

SARS-CoV-2 mRNA vaccine boosters crucial in maintaining neutralizing antibodies in HCPs

Researchers evaluate the effects of a third dose of the BNT162b2 mRNA vaccine on antibody titers and breakthrough infections in healthcare workers.

4 Jan 2022

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

Researchers investigate the capacity of vaccine-induced antibodies to generate Fc-effector activity against the SARS-CoV-2 Omicron variant.

3 Jan 2022

Minimal nAb titers against Omicron in the elderly after 3rd dose

Researchers measured titers of cross-protective neutralizing antibodies against SARS-CoV-2 after they had received a third booster dose.

3 Jan 2022

SARS-CoV-2 Omicron study on hamsters, shows virus results in a less severe disease

Researchers investigate the ability of immunity acquired from SARS-CoV-2 wild-type infection to protect against the Omicron variant in Syrian hamster models.

3 Jan 2022

SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

BNT162b2 booster restores protection following waning of the 2-dose vaccine

Researchers assess the real-world effectiveness of a third booster dose of the Pfizer-BioNTech BNT162b2 vaccine against the initial two-dose regimen.

29 Dec 2021

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

A new study found that the presence of a subset of antibodies with broad neutralizing activities against all circulating variants of concern in the three-dose vaccines' memory B-derived antibody repertoire suggests that the Omicron/future variants infection may elicit selective and rapid recall of humoral responses, conferring secondary protection directed by memory etched in the immune system.

29 Dec 2021

Exploring immunogenicity and safety after a homologous booster dose of SARS-CoV-2 recombinant spike protein vaccine

Research suggests that a single booster dose of NVX-CoV2373 given approximately six months after the primary series induced significant increases in humoral antibodies, while also exhibiting an acceptable safety profile.

29 Dec 2021

Double-dose mRNA COVID vaccines effective among dialysis patients

Researchers assess the impact of lesser initial vaccine response and subsequent waning antibody levels on clinical outcomes among maintenance dialysis.

28 Dec 2021

Exploring immunity and severe disease caused by the SARS-CoV-2 Omicron variant

A new study describes the findings of a seroprevalence survey intended to establish the infection rates and the incidence of severe COVID-19 through December 15, 2021, in Gauteng, a crowded province that compresses a quarter of the country’s people into less than 2% of its area.

23 Dec 2021

COVID can affect sperm quality for three months

Researchers determine whether SARS-CoV-2 could cross the blood-testis barrier and be detected in human semen after infection.

22 Dec 2021

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

In cancer, a major obstacle to anti-tumor immunity and immunotherapy treatment is the infiltration of regulatory T cells, or T-reg cells, into a tumor. These immune cells generally turn down the immune response, and they can prevent the immune system from destroying cancer cells.

22 Dec 2021

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

Researchers investigate the possible relationship between COVID-19 vaccination and the incidences of Guillain-Barre syndrome.

21 Dec 2021

Immunoglobulin News and Research

Broad cross-neutralization antibodies found to be effective against SARS-CoV-2 Omicron variant

Evaluating the response of lung cancer patients to COVID-19 mRNA vaccination

Antibody binding response significantly reduced for Omicron compared to other SARS-CoV-2 variants

Serological antibody response to SARS-CoV-2 infection at a population level

Booster dose elicits cross-reactive humoral immunity against SARS-CoV-2 Delta and Omicron variants

COVID-19 mRNA vaccines offer protection against Omicron variant in pregnancy

Transplant recipients benefit from a COVID-19 vaccine booster

SARS-CoV-2 mRNA vaccine boosters crucial in maintaining neutralizing antibodies in HCPs

Omicron spike-specific binding antibodies attenuate disease, despite increasing transmission

Minimal nAb titers against Omicron in the elderly after 3rd dose

SARS-CoV-2 Omicron study on hamsters, shows virus results in a less severe disease

SARS-CoV-2 infection and immunity in pregnancy and fetal development

BNT162b2 booster restores protection following waning of the 2-dose vaccine

3-dose vaccines deemed ultrapotent against diverse and highly transmissible SARS-CoV-2 Omicron and other variants

Exploring immunogenicity and safety after a homologous booster dose of SARS-CoV-2 recombinant spike protein vaccine

Double-dose mRNA COVID vaccines effective among dialysis patients

Exploring immunity and severe disease caused by the SARS-CoV-2 Omicron variant

COVID can affect sperm quality for three months

Transcription factor Blimp1 identified as potential target for modulating T-reg activity to treat cancer

UK research investigates relationship between COVID-19 vaccination and Guillain-Barré syndrome

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