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Research explores complex relationship between cholesterol and breast cancer risk

Research explores the complex relationship between cholesterol and breast cancer risk, with some studies suggesting an increased risk with elevated cholesterol levels while others find an inverse association.

15 Jun 2023

Gut microbiota holds clues to predicting Alzheimer's risk

Gut microbiome alterations in preclinical Alzheimer's disease (AD) were investigated, revealing distinct taxonomic composition and potential markers of AD risk. These findings contribute to understanding AD pathology and offer insights into gut-derived markers for AD.

15 Jun 2023

Study reveals impressive skin benefits of blueberries

The benefits of topical and dietary blueberry supplementation in preventing environmental stressor-mediated skin damage and preserving skin health.

14 Jun 2023

Study finds altered gut bacteria in people with early signs of Alzheimer's disease

People in the earliest stage of Alzheimer's disease - after brain changes have begun but before cognitive symptoms become apparent - harbor an assortment of bacteria in their intestines that differs from the gut bacteria of healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

14 Jun 2023

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

13 Jun 2023

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

A human or animal's microbiome - the collection of often beneficial microorganisms, including as bacteria and fungi, that live on or within a host organism - can play an important role in the host's overall immune response, but it is unclear how vaccines against harmful pathogens impact the microbiome.

11 Jun 2023

Sea cucumbers could be key ingredient in preventing diabetes

Sea cucumbers are a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research from the University of South Australia.

10 Jun 2023

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

Two new studies in Science and Science Immunology spotlight a group of intestinal T cells with α4β7 integrin receptors that could be targeted to prevent resistance to immune checkpoint blockade (ICB) cancer immunotherapy.

8 Jun 2023

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Researchers evaluated the presence of coronavirus disease 2019 (COVID-19) drugs in river water.

8 Jun 2023

Shifting towards precision medicine for type 2 diabetes dietary management

Researchers reviewed existing data on the genetic factors and the gene-diet interactions that could alter dietary management of type 2 diabetes.

8 Jun 2023

Study reveals surprising link between biological age and child development

Study explores the relationship between accelerated biological age in children, as indicated by telomere length and DNA methylation age, and various developmental outcomes. It aims to clarify the impact of accelerated biological age on growth, cognition, behavior, lung function, and puberty onset in European school-age children.

7 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

Endophytic fungi Penicillium verhagenii: an exploration of its anticancer, antioxidant, antimicrobial, and larvicidal activity

Researchers explored the use of endophytic fungi to fabricate selenium nanoparticles.

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Freiburg researchers gain new insights into metabolic processes in the kidney

Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights into metabolic processes in the kidney.

5 Jun 2023

Mediterranean diet in pregnancy: A recipe for reduced stress and improved sleep

A Mediterranean diet intervention during pregnancy reduces maternal stress and anxiety levels, improves sleep quality, and increases the cortisone/cortisol ratio. These findings highlight the positive impact of dietary changes on maternal well-being during gestation.

4 Jun 2023

Novel technology helps analyze tumor growth in another dimension

Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets.

2 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Researchers investigated the influence of structured Mediterranean diet intervention on the anxiety and stress levels.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Metabolites News and Research

Research explores complex relationship between cholesterol and breast cancer risk

Gut microbiota holds clues to predicting Alzheimer's risk

Study reveals impressive skin benefits of blueberries

Study finds altered gut bacteria in people with early signs of Alzheimer's disease

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Vaccine against deadly chytrid fungus shifts microbiome to make frogs more resilient to future exposure

Sea cucumbers could be key ingredient in preventing diabetes

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Shifting towards precision medicine for type 2 diabetes dietary management

Study reveals surprising link between biological age and child development

Shaping the human metabolome: the impact of a ketogenic diet

Endophytic fungi Penicillium verhagenii: an exploration of its anticancer, antioxidant, antimicrobial, and larvicidal activity

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Freiburg researchers gain new insights into metabolic processes in the kidney

Mediterranean diet in pregnancy: A recipe for reduced stress and improved sleep

Novel technology helps analyze tumor growth in another dimension

Peptidomimetic antibiotics may be effective against resistant bacteria

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Multi-ethnic genome study unlocks new genetic links to health conditions

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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