Mitochondria News and Research

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Combining Western-style high-fat diet with antibiotic use increases risk of pre-IBD

UC Davis researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre-inflammatory bowel disease (pre-IBD).

14 Jul 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

Fatty acid can kill human cancer cells, study shows

Researchers have demonstrated that a fatty acid called dihomogamma-linolenic acid, or DGLA, can kill human cancer cells.

11 Jul 2020

Scientists discover promising therapy to combat the growing epidemic of liver disease

In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in preclinical mouse models, according to researchers at the University of Colorado Anschutz Medical Campus.

8 Jul 2020

New discovery helps explain heart defects in Barth syndrome

The heart needs energy to pump blood. So, energy production defects in heart muscles result in a variety of cardiac diseases.

7 Jul 2020

New vitamin K-based drug eliminates medication-resistant epileptic seizures in mice

In the cover article of the June 11 issue of the Journal of Medicinal Chemistry, a team of researchers at the Medical University of South Carolina, led by Sherine Chan, Ph.D., and James Chou, Ph.D., reports that a new vitamin K-based drug has proved effective in mouse models of medication-resistant seizures.

6 Jul 2020

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress - a new study confirms.

3 Jul 2020

UCLA scientists identify new function for histones

UCLA scientists have identified a new function for histones, the spool-shaped proteins that regulate gene expression and serve as anchors for strands of DNA to wrap around.

2 Jul 2020

Study identifies a promising way to delay the onset of Alzheimer's disease

Currently we are facing a dementia epidemic, estimations showing that by 2050 approximately 131 million people will be affected. Every 7 seconds a patient is diagnosed worldwide.

2 Jul 2020

Novel method shows how cell membranes are damaged by 'Parkinson's protein'

In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain.

2 Jul 2020

Oxidized charcoal nanoparticles can help treat COVID-19 patients

Artificial enzymes made of treated charcoal could have the power to curtail damaging levels of superoxides, radical oxygen ions that are toxic at high concentrations.

2 Jul 2020

Researchers develop computational approaches that dramatically reduce image-analysis time

A picture is worth a thousand words -but only when it's clear what it depicts. And therein lies the rub in making images or videos of microscopic life.

30 Jun 2020

Study: Staring at deep red light can significantly improve declining eyesight

Staring at a deep red light for three minutes a day can significantly improve declining eyesight, finds a new UCL-led study, the first of its kind in humans.

29 Jun 2020

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

University of Connecticut researcher Dr. George Wu recently published a paper in the Journal of Gastroenterology and Hepatology outlining his successful experiment delivering mitochondria to liver cells.

25 Jun 2020

Tiny protein in mitochondria has a big impact on health and longevity, study shows

A new study led by researchers at the USC Leonard Davis School of Gerontology is the first to demonstrate that a tiny protein has a big impact on health and longevity in both animals and humans.

24 Jun 2020

New technique helps measure dNTP concentrations with greater sensitivity

A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer.

24 Jun 2020

Researchers develop method to assess mitochondrial respiration in frozen tissues

Scientists led by Dr. Orian Shirihai, director of the metabolism theme at the David Geffen School of Medicine at UCLA, have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples, even years after they have been collected.

23 Jun 2020

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Cyclic peptide molecules of the fungal origin called cyclosporins were discovered in 1970's, and cyclosporin A soon became an important drug due to its immunosuppressive activity.

18 Jun 2020

Exercise has profound protective effect in mouse models of Friedreich's ataxia

A top exercise researcher at the University of Virginia School of Medicine is urging clinical trials of exercise in patients with Friedreich's ataxia after finding that physical activity has a "profound" protective effect in mouse models of the debilitating genetic disease.

16 Jun 2020

Study: Exposure to air particulate matter impairs metabolism of olfactory mucosal cells

Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study from the University of Eastern Finland. The results can contribute to a better understanding of how air pollutants may harm brain health, as the olfactory mucosa can act as a key pathway to the brain.

15 Jun 2020

Mitochondria News and Research

Combining Western-style high-fat diet with antibiotic use increases risk of pre-IBD

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Fatty acid can kill human cancer cells, study shows

Scientists discover promising therapy to combat the growing epidemic of liver disease

New discovery helps explain heart defects in Barth syndrome

New vitamin K-based drug eliminates medication-resistant epileptic seizures in mice

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

UCLA scientists identify new function for histones

Study identifies a promising way to delay the onset of Alzheimer's disease

Novel method shows how cell membranes are damaged by 'Parkinson's protein'

Oxidized charcoal nanoparticles can help treat COVID-19 patients

Researchers develop computational approaches that dramatically reduce image-analysis time

Study: Staring at deep red light can significantly improve declining eyesight

Groundbreaking experiment marks first successful delivery of mitochondria to liver cells

Tiny protein in mitochondria has a big impact on health and longevity, study shows

New technique helps measure dNTP concentrations with greater sensitivity

Researchers develop method to assess mitochondrial respiration in frozen tissues

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Exercise has profound protective effect in mouse models of Friedreich's ataxia

Study: Exposure to air particulate matter impairs metabolism of olfactory mucosal cells

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