Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Targeting PCS may help improve health of patients with chronic kidney disease

Insulin resistance, or prediabetes, in individuals with kidney disease may be caused by the progressive retention of certain compounds that are normally excreted by the kidneys in healthy individuals, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

21 Dec 2012

Slushy spares kidney during partial nephrectomy

US researchers report the success and feasibility of a novel method of carrying out partial nephrectomy in kidney patients, using minimally invasive surgery.

20 Dec 2012

Pharmalink commences Nefecon Phase IIb study in primary IgA nephropathy

Pharmalink AB, a Swedish specialty pharma company, today announces it has initiated a Phase IIb study with Nefecon (Nefigan) in patients with primary IgA nephropathy at risk of developing end-stage renal disease.

18 Dec 2012

High AngII levels put stress on the ER and cause hypertension

When the heart works too hard, the brain may be to blame, says new Cornell University research that is changing how scientists look at high blood pressure (hypertension). The study, published in the Journal of Clinical Investigation in November, traces hypertension to a newfound cellular source in the brain and shows that treatments targeting this area can reverse the disease.

18 Dec 2012

Partial nephrectomy maintains renal function in cT1a RCC

Partial nephrectomy offers a similar magnitude of benefit in patients with clinical T1b versus cT1a renal cell carcinoma, Japanese researchers have shown.

17 Dec 2012

Study tracks movements of leukocytes through the kidney

Better targeted treatments for 20 per cent of renal failure patients are on the horizon following a key discovery about the role of white blood cells in kidney inflammation.

16 Dec 2012

Paroxetine could treat vascular complications of diabetes

University of Texas Medical Branch at Galveston researchers have discovered that the commonly used antidepressant drug paroxetine could also become a therapy for the vascular complications of diabetes.

14 Dec 2012

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

Abnormalities of mineral metabolism worsen with progressive chronic kidney disease (CKD) and are linked with a higher risk for kidney failure among African Americans, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

New technique may allow more kidney cancer patients to avoid conventional open surgery

Urologists at Henry Ford Hospital have developed a new technique that could make minimally invasive robotic partial nephrectomy procedures the norm, rather than the exception for kidney cancer patients. The technique spares the kidney, eliminates long hospital stays and provides better outcomes by giving the surgeon more time to perform the procedure.

14 Dec 2012

Swift Charities donates $15,262 to Waylon Jennings Fund for Diabetes Research at TGen

Swift Charities, the charitable arm of Swift Transportation, today donated $15,262 to The Waylon Jennings Fund for Diabetes Research at the Translational Genomics Research Institute (TGen).

14 Dec 2012

Ultradian Diagnostics announces publication of clinical study results for Biologue

Ultradian Diagnostics LLC, an early-stage medical device company based in Rensselaer, New York, today announced the publication of clinical study results for Biologue, the Company's minimally invasive continuous glucose monitoring (CGM) system, in the November 2012 issue of the Journal of Diabetes Science and Technology.

13 Dec 2012

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

FibroGen, Inc., and Astellas Pharma Inc., announced today the initiation of the first clinical study in the Phase 3 clinical development program of FG-4592/ASP1517, an orally administered small molecule, for treatment of anemia associated with chronic kidney disease ("CKD") in patients not on dialysis and on dialysis, to support approval in the U.S. and Europe.

12 Dec 2012

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

AMAG Pharmaceuticals, Inc. today announced that new data from two pivotal phase III clinical trials were presented at the American Society of Hematology's (ASH) annual meeting in Atlanta, Georgia.

11 Dec 2012

Modified CKD model aids risk prediction in African Americans

Screening African Americans for microalbuminuria at either 5- or 10-year intervals would be highly cost-effective using a modified version of the CKD Health Policy Model, US researchers report.

7 Dec 2012

Study reveals increase in incidence of dialysis-requiring acute kidney injury

Acute kidney injury (AKI), an abrupt or rapid decline in kidney function, is a serious and increasingly prevalent condition that can occur after major infections, major surgery, or exposure to certain medications.

7 Dec 2012

University of Michigan to create National Kidney Disease Registry

The University of Michigan Kidney Epidemiology and Cost Center will create a National Kidney Disease Registry to monitor kidney disease among America's veterans.

7 Dec 2012

Health Improvement Institute announces winners of 2012 Aesculapius Award

Aesculapius Awards of Excellence for 2012 were announced today by Dr. Peter G. Goldschmidt, President and Founder of the Health Improvement Institute.

6 Dec 2012

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Even in Florida, where Republican leaders led the legal battle against Obamacare, there's recognition now that the state has to act fast to comply with the new law. ... After Nov. 6, Gov. Rick Scott had a change in tone. "Gov. Mitt Romney did not win the election. So, it's not an option to repeal Obamacare," he said. "So, my goal now is to focus on what's good for our citizens." But Republicans are having trouble convincing Tea Party activists that the fight is over.

6 Dec 2012

Baxter enters definitive agreement to acquire Gambro

Baxter International Inc. has entered into a definitive agreement to acquire Gambro AB, a privately held dialysis product company based in Lund, Sweden, for total consideration of 26.5 billion SEK (approximately $4.0 billion USD at current exchange rates).

From Baxter International Inc. 5 Dec 2012

Nephropathy News and Research

Further Reading

Targeting PCS may help improve health of patients with chronic kidney disease

Slushy spares kidney during partial nephrectomy

Pharmalink commences Nefecon Phase IIb study in primary IgA nephropathy

High AngII levels put stress on the ER and cause hypertension

Partial nephrectomy maintains renal function in cT1a RCC

Study tracks movements of leukocytes through the kidney

Paroxetine could treat vascular complications of diabetes

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Mineral metabolism abnormalities may increase risk of kidney failure among African Americans

New technique may allow more kidney cancer patients to avoid conventional open surgery

Swift Charities donates $15,262 to Waylon Jennings Fund for Diabetes Research at TGen

Ultradian Diagnostics announces publication of clinical study results for Biologue

Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia

AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting

Modified CKD model aids risk prediction in African Americans

Study reveals increase in incidence of dialysis-requiring acute kidney injury

University of Michigan to create National Kidney Disease Registry

Health Improvement Institute announces winners of 2012 Aesculapius Award

Roundup: Florida health law battles take new turn; Oklahoma court rejects anti-abortion law; Calif. kids Medi-Cal dispute continues

Baxter enters definitive agreement to acquire Gambro

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