Nucleotide News and Research

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Engineers crack the code to quickly diagnose anti-malarial drug resistance

One of the keys to quickly diagnosing anti-malarial drug resistance -- potentially saving lives -- lies in testing whole blood instead of extracting DNA, eliminating processing steps that can take hours or days.

13 Jun 2019

New assay uses a drop of blood to detect patients' resistance to antimalarial drugs

Antimalarial drugs appear to follow a typical pattern, with early effectiveness eventually limited by the emergence of drug resistance.

13 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Telomere shortening in adulthood is not caused by smoking, say researchers

A new study suggests that telomere length in adults should be regarded as a static biomarker that does not significantly change during adult life.

7 Jun 2019

Study uncovers new oncogenic function of receptor associated with Alzheimer's disease

Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease.

28 May 2019

Researchers develop simple, quick technique for gene editing in rice blast fungus

CRISPR/Cas9 is now a household name associated with genetic engineering studies.

24 May 2019

Common genetic variant associated with increased food intake and weight gain

Researchers have discovered that children who do not have obesity, but who are at risk for the chronic disease due to a common genetic variant eat more, according to a new study to be published in the June 2019 issue of Obesity.

23 May 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Researchers identify metabolic signatures to help diagnose, treat and prevent cervical cancer

Researchers at the University of Arizona have completed the first-of-its-kind study that could aid in the treatment, diagnosis and prevention of cervical cancer by identifying cervicovaginal metabolic signatures, or "fingerprints" that distinguish patients with HPV, pre-cancerous cervical conditions and cancer.

15 May 2019

Harvard scientists uncover key mechanism that allows viruses to replicate

Viruses are masterful invaders. They cannibalize host cells by injecting their genetic material, often making thousands of copies of themselves in a single cell to ensure their replication and survival.

13 May 2019

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Most antibiotics work by interfering with critical functions such as DNA replication or construction of the bacterial cell wall.

10 May 2019

Study explains why some football players with SCT experience adverse clinical outcomes

A recent study published in Southern Medical Journal, led by researchers from the University of South Florida identifies a genetic variation known to affect sickle cell disease symptomology.

10 May 2019

Genetic test for low birth weight on the horizon

Researchers have successfully identified 190 genetic factors associated with a low birth weight. They hope that this may one day be used to develop a universal genetic test.

3 May 2019

Combination of biological markers and genetic changes can predict radiation sensitivity

Latest results from a project to discover what makes a cancer patient more likely to suffer adverse side-effects after radiotherapy have shown that a combination of biological markers and certain genetic changes can predict radiation sensitivity.

30 Apr 2019

New study delves deeper into individual genomic differences than ever before

Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from structural variants, which include additions, deletions and rearrangements of large segments of DNA.

17 Apr 2019

Molecule metabolite variations in breast milk may hold risk factors for childhood obesity

New research suggests the composition of breast milk in normal weight mothers differs from that of overweight mothers, and that variations in small molecule metabolites found in breast milk are possible risk factors for childhood obesity.

11 Apr 2019

Study suggests novel therapeutic strategy for ALS

In a study published online in Brain on April 1, researchers from Dr. XU Jin's lab at the Institute of Neuroscience of the Chinese Academy of Sciences and their collaborators revealed a new cellular mechanism for amyotrophic lateral sclerosis, suggested a novel therapeutic strategy targeting the RNA degradation pathway, and identified an asthma drug as a potential medication for ALS.

9 Apr 2019

Air Force develops genetic test to predict mental performance

A research psychologist at the Air Force Research Laboratory can predict your mental performance from a cheek swab or blood sample.

22 Mar 2019

Knowing causative genes of osteoporosis may open door to more effective treatments

Scientists have harnessed powerful data analysis tools and three-dimensional studies of genomic geography to implicate new risk genes for osteoporosis, the chronic bone-weakening condition that affects millions of people.