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New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.

22 Oct 2025

Understanding the neural mechanisms behind food choices

Feeding in mammals is controlled by a complex neural system. Although several key neural pathways related to total calorie intake have been extensively studied, it is still unclear how food choices are regulated and how they influence overall feeding behavior.

22 Oct 2025

New drug combination shows promise in treating colorectal cancer

Colorectal cancer is one of the most common tumors among people over the age of 50. Although it is known to develop from small lesions or polyps, its exact causes are unknown — only a few risk factors are known — and it is usually treated with surgery, chemotherapy and radiotherapy, or biological therapies.

22 Oct 2025

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.

22 Oct 2025

Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport mechanisms, and role in protecting the brain from toxins. The paper highlights how BBB dysfunction contributes to neurological diseases and explores emerging technologies to overcome drug delivery challenges.

21 Oct 2025

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

21 Oct 2025

New discovery could someday help prevent breast cancer recurrence

Know someone who's been diagnosed with breast cancer? There's a good chance that person has received hormone therapy.

21 Oct 2025

New study offers hope for patients with treatment-resistant focal epilepsy

About one-third of patients with focal epilepsy, a common form of the neurological disorder, are believed to respond poorly to available therapies.

21 Oct 2025

Study provides a new approach for the treatment of prostate tumors

An international research team led by the Medical University of Vienna has demonstrated for the first time that thyroid hormone plays a key role in the development and progression of prostate cancer.

21 Oct 2025

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.

21 Oct 2025

Novel combination therapy shows promise for advanced neuroendocrine tumors

A novel combination therapy pairing a DNA-synthesis inhibitor with a targeted radiopharmaceutical may improve outcomes for patients with advanced neuroendocrine tumors, according to new clinical trial data presented this week at the European Society for Medical Oncology (ESMO) Congress 2025.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

Oral combination regimen improves survival in ER-positive HER-2-negative breast cancer

Patients with estrogen-receptor-positive HER-2-negative advanced breast cancer showed significantly improved progression-free survival when treated with an oral combination regimen that includes giredestrant, a novel, next-generation selective estrogen receptor degrader and full antagonist, compared to a standard combination approach.

18 Oct 2025

Nanoparticles offer new hope for treating alcohol-related liver disease

Across the world, more than 1.5 billion people suffer from chronic liver disease. The U.S. Centers for Disease Control and Prevention reports that it kills more than 52,000 people a year in the United States alone - the ninth most common cause of death in the nation.

17 Oct 2025

Osimertinib plus chemotherapy improves survival in EGFR-mutated lung cancer

Treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared to osimertinib alone.

17 Oct 2025

GLP-1 drugs like Ozempic may slow how quickly alcohol hits the bloodstream

Preliminary study shows GLP-1 receptor agonists alter alcohol response, suggesting potential for reducing cravings and intoxication in obese individuals.

17 Oct 2025

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Pulmonary fibrosis is a deadly disease in which the lungs become thickened and scarred, gradually losing their ability to deliver oxygen to the body.

16 Oct 2025

Study reveals how gut fungi influence the brain’s dopamine response to alcohol

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have found a surprising connection between a fungus associated with alcohol use disorder and the brain's dopamine reward pathway.

16 Oct 2025

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Breast cancer is the most common cancer among women worldwide (WHO, 2023). The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) has now developed a new therapy in a clinical study that tailors hormone treatment for breast cancer to the individual patient.

16 Oct 2025

Receptor News and Research

New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Understanding the neural mechanisms behind food choices

New drug combination shows promise in treating colorectal cancer

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Discovery offers a breakthrough approach to combat prostate tumor growth

Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

New discovery could someday help prevent breast cancer recurrence

New study offers hope for patients with treatment-resistant focal epilepsy

Study provides a new approach for the treatment of prostate tumors

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

Novel combination therapy shows promise for advanced neuroendocrine tumors

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Oral combination regimen improves survival in ER-positive HER-2-negative breast cancer

Nanoparticles offer new hope for treating alcohol-related liver disease

Osimertinib plus chemotherapy improves survival in EGFR-mutated lung cancer

GLP-1 drugs like Ozempic may slow how quickly alcohol hits the bloodstream

Blocking key protein restores healthy lung function and reduces fibrosis in mice

Study reveals how gut fungi influence the brain’s dopamine response to alcohol

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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