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Online asthma management program can help asthma patients

An online asthma management program can help asthma patients get top-rate care and overcome barriers to healthcare access, according to a study presented at the American Thoracic Society International Conference on May 22.

22 May 2005

People with chronic cough are often depressed

More than half of people with chronic cough-a nagging cough that can last for months or even years-suffer from depressive symptoms, according to a study to be presented at the American Thoracic Society International Conference on May 23.

22 May 2005

Commonly prescribed incontinence drug may help control symptoms of overactive bladder

When taken orally, trospium chloride not only helps control symptoms of overactive bladder systemically, but according to this study, it also may help control symptoms in the bladder itself when it comes into contact with the bladder walls.

22 May 2005

Researchers have isolated two biomarkers for interstitial cystitis (IC)

The discovery of these biomarkers could lead to a definitive test for IC and have the potential to lead to new therapies. Results of two studies are being presented today at the annual meeting of the American Urological Association (AUA) in San Antonio, and are published in abstracts 69 and 80 of the AUA proceedings.

22 May 2005

New insight into the machinery cells use to internalize cell surface receptors

Using state of the art imaging technology a team from Yale School of Medicine has glimpsed one of the cell's most important 'nano-machines' in action. The work, performed in collaboration with English and French scientists, provides new insight into the machinery cells use to internalize cell surface receptors.

22 May 2005

Novel way of administering an anti-cancer drug to bone-marrow transplant patients using continuous infusion

The new method achieves more predictable, stable drug levels in patients than the current method and could eventually allow doctors to more accurately adjust doses to accommodate individual differences in metabolism, thus increasing treatment effectiveness while avoiding side effects, said University of North Carolina at Chapel Hill researchers.

20 May 2005

Crucial to develop set of protections for women who donate eggs to stem cell research

Now that stem cell researchers have devised an efficient way of creating new human embryonic stem cell lines, biomedical ethicists at the Stanford University School of Medicine say it's crucial to develop a unique set of protections for the women who donate their eggs to make the research possible.

20 May 2005

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Dextromethorphan, an over-the-counter medication that silences coughs, may help fibromyalgia patients quiet over-reacting nerves that amplify ordinary touches into agony.

20 May 2005

Revalidation must have public confidence, says BMA

Whatever system of revalidation is chosen for doctors, the British Medical Association (BMA) believes it must have the confidence of the public, best achieved through a transparent professionally-led process. To succeed, says the BMA, revalidation must be seen to promote high standards, detect poor practice and have strategies for improving a doctor's performance where this is needed.

20 May 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

Study holds implications for gene therapy and stem cell biology

The study, conducted by scientists from Cincinnati Children's Hospital Medical Center, and Hannover Medical School and Hamburg University in Germany, reveals important evidence that tells us more about how blood forming stem cells regenerate. On the other hand, scientists offer caution in regards to the side effects associated with genetic engineering of stem cells.

20 May 2005

Researchers find first gene for inherited testicular cancer in mice

In this week's journal Nature, researchers report finding the first gene responsible for inherited susceptibility of testicular cancer in mice. The Ter mutation occurs in a gene called dead end, which is involved in normal testicular development and which may play a role in inherited forms of a testicular cancer occurring in infants.

20 May 2005

Extolling the safety of childhood vaccinations may only serve to strengthen the positions of those philosophically opposed to them

"Changing attitudes about pediatric vaccination can be challenging," says Dr. Kumanan Wilson, professor of medicine and health policy, management and evaluation at U of T, internal medicine physician at Toronto General Hospital, University Health Network, and lead author of the research.

20 May 2005

Chest CT can be first step to identifying if patient has had a heart attack

When radiologists are looking at contrast-enhanced chest CT examinations, they should take a look at the patient's heart to rule out heart attack, regardless of why the chest CT examination is being performed, a new study shows.

20 May 2005

Cetuximab (Erbitux) can battle cancer and prolong life in many patients with advanced colorectal cancer

"Even in people who have gone through six or more previous courses of chemotherapy, cetuximab, may fight the growth of cancer, giving patients additional months of life," says study presenter Heinz-Josef Lenz, M.D., associate professor of medicine at the Keck School of Medicine of the University of Southern California and USC/Norris Comprehensive Cancer Center.

20 May 2005

Cystatin-C, a new blood test for kidney function, is a better predictor of death and cardiovascular risk among the elderly

Investigators for NHLBI's Cardiovascular Health Study compared the two measures of kidney function, cystatin-C and the standard test creatinine, as predictors of death from all causes, death from cardiovascular causes, and incidence of heart attack and stroke among 4,637 elderly participants in the study.

20 May 2005

Sigmoidoscopy comes up short for women in detection of polyps in the colon

A new multi-center study has reaffirmed the difference between the sexes – at least when it comes to colorectal cancer detection and prevention.

20 May 2005

Infants with Krabbe disease saved by cord blood stem cells

Children with a fatal genetic disorder called Krabbe Disease can be saved and their brain development preserved if they receive stem cells from umbilical cord blood before symptoms of the disease develop, according to a study published in the current issue of the New England Journal of Medicine.

20 May 2005

New kidney test better elder mortality predictor

A study at the San Francisco VA Medical Center (SFVAMC) has found that a test of kidney function that measures blood levels of cystatin C -- a protein produced by most cells in the body -- is a far more accurate predictor of mortality risk in elderly people than the current standard kidney function test, which measures levels of the protein creatinine.

20 May 2005