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Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell.

5 May 2005

Episiotomy usually provides no benefits

According to a systematic review of existing studies, to appear in the May 4 issue of the Journal of the American Medical Association, the surgical procedure known as an episiotomy, performed in up to 35 percent of U.S. vaginal births, usually provides no benefits.

5 May 2005

Survey of ED doctors shows team-based stroke care, risk-reducing measures, needed to increase use of tPA

Forty percent of emergency physicians say they're unlikely to give stroke patients the only FDA-approved drug shown to improve their prognosis, even in an ideal setting, mostly because of the fear of causing brain bleeding.

5 May 2005

Research is first to test effectiveness of a new patch for treating ADHD

A new University at Buffalo study of treatments for children with attention deficit hyperactivity disorder (ADHD) has found that combining behavior modification therapy with medication is the most effective way to improve the behavior of many ADHD children.

5 May 2005

Drug safety in the doctor’s office - nearly half of patients have lapses in monitoring

According to research published in the Journal of General Internal Medicine, only slightly more than half of patients taking chronic medications received the recommended laboratory tests to monitor drug side effects.

5 May 2005

Physician assisted suicide and why patients are motivated to seek death

Patients motivated to seek a doctor for their death wish did so after a deliberative and thoughtful process rather than on impulse, according to a research study published in the Journal of General Internal Medicine .

5 May 2005

Cranberries good for the heart

Compounds that occur naturally in cranberries may be good for the heart, researchers at the University of Wisconsin-Madison have found.

5 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Serious concerns about the use of morphine in heart patients

While patients hospitalized for a heart attack have long been treated with morphine to relieve chest pain, an analysis by researchers from the Duke Clinical Research Institute has shown that these patients have almost a 50 percent higher risk of dying.

5 May 2005

Scientists extend the lifespan of mice

Scientists at the University of Washington and their colleagues at other research centers have found a way to significantly extend the lifespan of mice while reducing the impact of the aging process. Their study, which will be published online by the journal Science on May 5, lends more credence to the free-radical theory of aging.

5 May 2005

After surgery check colon tumors for signs of syndrome, study suggests

A new study suggests that, after surgery, all colon tumors should be tested to learn if the patient may have an inherited syndrome that carries an extremely high risk of cancer. It also suggests that this prescreening can be done using a relatively inexpensive microscopy test already used in hospital pathology laboratories.

5 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Different consultants mean different lengths of stay in hospitals

Patients may enjoy shorter stays in hospitals depending on which consultant looks after them, according to new research published this week in Postgraduate Medical Journal.

4 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Fear stops some parents vaccinating their children

A new study has found that the majority of parents who choose not to vaccinate their children do so out of fear that the vaccine will cause more harm than the disease it prevents.

4 May 2005

National survey reveals critical barriers to improving women's health

For American women, being healthy is far more than getting a good checkup or being disease-free. According to "Women Talk," the first annual national women's health survey from the National Women's Health Resource Center (NWHRC), being healthy means both physical and emotional wellness and having a healthy family.

4 May 2005

Internet may help prevent blindness in Medicaid patients with diabetes

A Wake Forest University Baptist Medical Center team is launching a high-tech study to determine if early screening using a special camera and images transmitted over the Internet can prevent blindness in Medicaid patients with diabetes.

4 May 2005

Pregnancy, no insurance don't mix, midwives say

Being uninsured and pregnant in this country should be recognized as a risk factor for the health of the mother and baby, said the American College of Nurse-Midwives (ACNM) as the organization marked Cover The Uninsured Week (May 1-8, 2005). ACNM is troubled by how this condition – uninsured and pregnant – is severely impacting the financial well-being of taxpayer-financed health care programs, while solutions such as broader access to midwifery care are left unexplored.

4 May 2005

Impact of acupuncture goes beyond the acknowledged placebo effect

Researchers at the University of Southampton and University College London have shown for the first time that the impact of acupuncture goes beyond the acknowledged placebo effect caused by the patient's own expectation of feeling benefit from the treatment.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005