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Research challenges the traditional explanation for the causes of diastolic heart failure

New research from Columbia University Medical Center is challenging the traditional explanation for the causes of the most common type of heart failure, traditionally called diastolic heart failure.

12 Apr 2005

New drugs help the immune system kill cancer cells

Researchers at the Lankenau Institute for Medical Research (LIMR) announced today that they have discovered an effective way to enlist the immune system to help chemotherapy destroy breast cancer cells. The work, led by LIMR researchers Alexander J. Muller and George C. Prendergast, is reported in the March 2005 edition of the leading international medical journal Nature Medicine.

11 Apr 2005

Tissue engineering to grow bone, ligaments and cartilage

A future in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major role in treating medical conditions was revealed at a recent Tissue Engineering Symposium at Wake Forest University Baptist Medical Center.

11 Apr 2005

Childhood asthma may be linked to grandmother's smoking

A child whose grandmother smoked while pregnant may have double the risk of developing childhood asthma, according to new research.

11 Apr 2005

Soy oil increases heart rate variability

Taking daily supplements of fish or soy oil may improve cardiac function and protect against heart attacks in the short-term. Study results published in the April issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians, are the first to show that soy oil increases heart rate variability (HRV), a measure of cardiac autonomic function.

11 Apr 2005

Dental patients agreeable to tobacco interventions

Dental patients don't mind if their dentists give them a nudge to stop using tobacco products, according to the findings of survey conducted at the Case Western Reserve University School of Dental Medicine.

11 Apr 2005

FDA approves Ambien CR for treatment of insomnia

Sanofi-aventis announced today that it has received an approvable letter from the U.S. Food and Drug Administration (FDA) for Ambien CR (zolpidem tartrate extended release) CIV. Ambien CR is the controlled-release formulation of zolpidem, the world's leading sleep aid.

11 Apr 2005

Giuliani report calls for moratorium on prescription drug importation

As the nation tightens its borders against possible future terrorist attacks, it risks undermining security and safety by opening them to non-FDA approved prescription drugs from other countries, according to a comprehensive report released today in New York City by Giuliani Partners, headed by former New York City Mayor Rudy Giuliani.

11 Apr 2005

Study predicted cardiovascular risk of Cox-2 inhibitors

Amid the recent controversy and confusion over serious side effects from pain medications, a new UCLA and Veterans Affairs Greater Los Angeles Healthcare System study demonstrates that for arthritis sufferers at high risk for gastrointestinal problems who traditionally may have used a drug like Vioxx, the most cost-effective and safest treatment is actually a common painkiller combined with an acid-reducing drug.

11 Apr 2005

New blood test improves the ability to diagnose or exclude congestive heart failure

A new blood test that measures a particular marker of cardiac distress can markedly improve the ability to diagnose or exclude congestive heart failure in patients with shortness of breath who come to hospital emergency departments.

11 Apr 2005

Moderate levels of exercise may not be enough to control mild hypertension

Moderate levels of exercise may not be enough to control mild hypertension in men and women over age 55, the age group most at risk of later developing potentially fatal heart failure, a new four-year study reports. The findings by researchers at Johns Hopkins, to be published in the journal Archives of Internal Medicine online April 11, call into question the effectiveness of national guidelines on exercise for lowering blood pressure in older people.

11 Apr 2005

Fifteen-year hunt uncovers gene behind pseudothalidomide syndrome

A team of scientists from Colombia, the United States and elsewhere has successfully completed a 15-year-plus search for the genetic problems behind the very rare Roberts syndrome, whose physical manifestations often include cleft lip and palate and shortened limbs that resemble those of babies whose mothers took thalidomide during pregnancy.

11 Apr 2005

Malaria's secret weapon revealed

A US-led international team of scientists have discovered how the deadliest malaria parasite is able to "hide" from the body's immune system.

10 Apr 2005

Now revealed that Salk polio vaccine was a team effort

The cure for polio came as a result of the collaboration between Thomas Francis Jr. and Jonas Salk.

10 Apr 2005

HIVNET 012 perinatal HIV prevention trial praised by IOM

The Institute of Medicine (IOM) of the National Academies of Sciences in the autumn of 2004 was asked by the NIH to review the HIVNET 012 perinatal HIV prevention trial and provide an assessment of the validity of the study results.

10 Apr 2005

Panel in US disputes drug trial allegations

Medical experts have been forced to defend a study conducted in Uganda and called HIVNET 012 that led to the widespread use of a single AIDS drug called nevirapine to protect newborns, after allegations by Dr. Jonathan Fishbein, a National Institutes of Health researcher, that the research was flawed and the conclusions were unfounded.

10 Apr 2005

Test of new HIV drug

A study under way at UAB aims to determine whether the first of a new class of HIV drugs is safe and effective in preventing the virus from entering healthy cells.

10 Apr 2005

Attacks on WHO staff - progress on Marburg epidemic halted

The World Health Organization (WHO) has suspended its efforts to contain the outbreak of the deadly Marburg virus in Angola, in the northern province of Uige, after staff in their mobile surveillance vehicles have been attacked.

10 Apr 2005

Novel human kidney protein called renalase that regulates both heart contraction and blood pressure

Researchers at Yale School of Medicine and the VA Connecticut Healthcare System in West Haven identified a novel human kidney protein called renalase that regulates both heart contraction and blood pressure; it is a strong candidate for easily administered treatment of advanced kidney and cardiovascular disease.

10 Apr 2005

Findings could lead to improved treatments for schizophrenics, amphetamine abusers

An Oregon Health & Science University researcher is among an international team closing in on why many people with schizophrenia and other psychotic disorders are "supersensitive" to the powerful neurotransmitter dopamine.

10 Apr 2005