Clinical Trial News and Research

RSS

Cytokine GM-CSF likely plays important role in MS

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

30 Apr 2015

Study opens door for new therapeutic approaches to treating patients with melanoma

Weill Cornell Medical College researchers have shown for the first time that a gene previously implicated in blood vessel formation during embryonic development and tumor growth also induces immune suppression during tumor development.

30 Apr 2015

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer.

30 Apr 2015

Medicure records net revenue of $3.3 million for first quarter 2015

Medicure Inc., a specialty pharmaceutical company, today reported its results from operations for the first quarter ended March 31, 2015.

30 Apr 2015

Fifth patient dosed in Benitec's TT-034 Phase I/IIa clinical trial for prevention of HCV infection

Benitec Biopharma, a biopharmaceutical company focused on providing potentially curative therapies with its proprietary gene-silencing technology called ddRNAi or "expressed RNAi," is pleased to advise that the fifth patient in the company's 'first in man', Phase I/IIa dose escalation clinical trial of TT-034 for hepatitis C virus (HCV) infection, has today, been dosed at the Duke Clinical Research Unit.

29 Apr 2015

One of the most important global healthcare studies of this generation reaches significant patient enrollment milestone

The TVC Imaging System is FDA-approved to identify lipid-core plaques that may cause heart attacks. Identification of such plaques would be a major step toward the development of percutaneous coronary intervention (PCI) as a means to prevent coronary events...

29 Apr 2015

SLU selected to work on universal flu vaccine project

Supported by a federal contract, Saint Louis University will study a concept for a universal flu vaccine that is designed to protect people from influenza pandemics that could turn deadly as well as seasonal flu caused by the influenza A virus.

29 Apr 2015

Adjustable gastric band surgery, weight management program offer similar benefits in diabetes patients

Weight loss is never easy, but it's important for overweight people with type 2 diabetes seeking to control their blood sugar levels and optimize their health. A small clinical trial among such patients led by Joslin Diabetes Center and Brigham and Women's Hospital researchers now has shown that two approaches--adjustable gastric band surgery and an intensive group-based medical diabetes and weight management program--achieved similar improvements in controlling blood sugar levels after one year.

29 Apr 2015

First patient enrolled in CryoLife's PerClot IDE clinical trial

CryoLife, Inc., a leading medical device and tissue processing company focused on cardiac and vascular surgery, announced today the enrollment of the first patient in its PerClot Investigational Device Exemption (IDE) clinical trial, the Company's pivotal clinical trial to gain approval to commercialize PerClot in the U.S.

28 Apr 2015

Luminex provides clinical trial update on ARIES HSV 1&2 Assay

Luminex Corporation today announced that testing at the clinical trial sites for the ARIES HSV 1&2 Assay is now complete. The next steps, including site to site reproducibility testing, followed by data analysis and assembly of the data package for submission to the FDA, are now underway.

From Luminex 28 Apr 2015

Stempeutics Research granted process patent in China for novel stem-cell based drug Stempeucel

Stempeutics Research, a group company of Manipal Education and Medical Group and a Joint Venture with Cipla Group, announced today that the State Intellectual Property Office of China granted a process patent for its novel stem-cell based drug Stempeucel.

28 Apr 2015

PCDx test performs better than FoundationOne test in clinical study

Data from a small cohort published OncoTargets and Therapy today shows that the Paradigm Cancer Diagnostic Test (PCDx) performed better than Foundation Medicine's FoundationOne test across a number of key clinical variables, including turnaround time (TAT) and clinically actionable biomarker targets.

28 Apr 2015

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

As the incidence of type 1 diabetes (T1D) rises worldwide, The Leona M. and Harry B. Helmsley Charitable Trust today announced the launch of an ambitious new T1D Prevention Initiative to investigate the early stages of development of the disease and identify new pathways to prevent it.

28 Apr 2015

Intarcia Therapeutics announces closing of $225 million synthetic royalty financing

Intarcia Therapeutics, Inc. today announced the closing of a $225 million synthetic royalty financing with an equity conversion option at a $5.5 billion Company valuation. Plans are to use these funds to accelerate the initiation of additional head-to-head comparative and switch studies of ITCA 650 vs. leading oral and injectable type 2 diabetes therapies.

28 Apr 2015

Boston Scientific, Brainlab form strategic collaboration

Boston Scientific Corporation announces a collaboration with Brainlab AG, a leading software-driven medical technology company that helps improve patient treatment planning and surgical navigation.

28 Apr 2015

Check-Cap announces Notice of Allowance from USPTO for endoscopy capsule technology

Check-Cap Ltd., a clinical stage medical diagnostics company engaged in the development of a preparation-free ingestible imaging capsule that utilizes low-dose X-rays for the screening for colorectal cancer, today announced receipt of a Notice of Allowance from the United States Patent and Trademark Office for patent application U.S. 13/825,018 entitled, "Estimation of Distances and Size of Lesions in the Colon with an Imaging Capsule."

27 Apr 2015

Resverlogix, Hepalink announce equity investment and license agreement for RVX-208

Resverlogix Corp. today announced that it has entered into a Framework Agreement which sets forth the principal business terms for an equity investment and a license of RVX-208, for all indications, to Shenzhen Hepalink Pharmaceutical Co., Ltd. for China, Hong Kong, Taiwan and Macau (the "Territories").

27 Apr 2015

Neuronetics completes Series F Financing Round

Neuronetics, Inc., the established market leader in transcranial magnetic stimulation (TMS) technology, announced today the completion of its Series F Financing Round, which included investment from GE Ventures, as well as its original investor base totaling $34.3 million.

27 Apr 2015

Merrimack completes submission of MM-398 NDA for treatment of post-gemcitabine metastatic pancreatic cancer

Merrimack Pharmaceuticals, Inc. and Baxter International Inc. today jointly announced that Merrimack has completed the rolling submission of the New Drug Application (NDA) for MM-398 (irinotecan liposome injection), also known as "nal-IRI," to the U.S. Food and Drug Administration.

From Baxter International Inc. 27 Apr 2015

Can-Fite announces favorable data from further analysis of CF101 Phase II/III study in patients with psoriasis

Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (TASE: CFBI), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today favorable data from further analysis of its Phase II/III double-blind, placebo-controlled study designed to test the efficacy of CF101 in patients with moderate-to-severe plaque psoriasis.

27 Apr 2015

Clinical Trial News and Research

Cytokine GM-CSF likely plays important role in MS

Study opens door for new therapeutic approaches to treating patients with melanoma

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Medicure records net revenue of $3.3 million for first quarter 2015

Fifth patient dosed in Benitec's TT-034 Phase I/IIa clinical trial for prevention of HCV infection

One of the most important global healthcare studies of this generation reaches significant patient enrollment milestone

SLU selected to work on universal flu vaccine project

Adjustable gastric band surgery, weight management program offer similar benefits in diabetes patients

First patient enrolled in CryoLife's PerClot IDE clinical trial

Luminex provides clinical trial update on ARIES HSV 1&2 Assay

Stempeutics Research granted process patent in China for novel stem-cell based drug Stempeucel

PCDx test performs better than FoundationOne test in clinical study

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

Intarcia Therapeutics announces closing of $225 million synthetic royalty financing

Boston Scientific, Brainlab form strategic collaboration

Check-Cap announces Notice of Allowance from USPTO for endoscopy capsule technology

Resverlogix, Hepalink announce equity investment and license agreement for RVX-208

Neuronetics completes Series F Financing Round

Merrimack completes submission of MM-398 NDA for treatment of post-gemcitabine metastatic pancreatic cancer

Can-Fite announces favorable data from further analysis of CF101 Phase II/III study in patients with psoriasis

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer