Efficacy News and Research

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Study uses gold nanoparticles to remove prostate cancer cells

A small clinical trial using gold nanoparticles that act as tumor-seeking missiles on a mission to remove prostate cancer has begun at The University of Texas Health Science Center at Houston (UTHealth). It is the first trial of its kind in the world.

9 Nov 2018

New multi-allergen test works just as well with dried blood

Using the Allergy Chip co-developed by MedUni Vienna, sensitization to allergens can be detected early on. This normally requires a doctor taking a blood sample for subsequent analysis in a laboratory equipped with the Chip.

8 Nov 2018

Scientists grow 3D, beating human heart tissue

Researchers at the University Medical Center Hamburg-Eppendorf have found a way to grow human heart tissue that can serve as a model for the atria of the heart.

8 Nov 2018

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

The aim of "precision medicine" is to devise individualized treatment strategies and therapies. Statistical methods play an important role in predicting the efficacy of drugs from clinical study data, based on patient characteristics.

8 Nov 2018

Cannabinoids hold promise in treating children with epilepsy

In recent years, cannabinoids--the active chemicals in medical marijuana-- have been increasingly touted as a potential treatment for a range of neurological and psychiatric disorders. In a Developmental Medicine & Child Neurology review, investigators compare their efficacy with antiepileptic drugs for children with epilepsy.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Researchers develop electroencephalography-based test to objectively measure pain

If you've ever visited the emergency department with appendicitis, or you're one of the 100 million U.S. adults who suffer from chronic pain, you're familiar with a row of numbered faces, with expressions from smiling to grimacing, used to indicate pain levels.

6 Nov 2018

New study supports use of antibiotic prophylaxis in patients undergoing invasive dental treatment

New research has revealed the impact a change in US guidelines had on the prescribing of antibiotic prophylaxis to prevent a life-threatening heart condition infective endocarditis in patients before undergoing invasive dental treatment.

5 Nov 2018

Experts identify barriers to using stroke-preventing anticoagulants in Canada

International guidelines recommend direct oral anticoagulants over warfarin to prevent stroke for most patients with atrial fibrillation.

5 Nov 2018

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Amgen today announced that new clinical data will be presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, Dec. 1-4, 2018. Data across an array of malignancies will be featured in 45 abstracts, including nine oral presentations, from the Company’s broad portfolio andearly-stage pipeline.

From AMGEN 5 Nov 2018

Cooling therapies may offer best protection against adverse effects of taxane-based chemotherapy

Due to their broad antitumor activity that inhibits the function of microtubules, taxanes are common chemotherapeutic agents utilized for the management of multiple cancer types from breast to prostate. Unfortunately, the frequency of their use is equally matched by the rates of expected and well known side effects.

2 Nov 2018

Lymph nodes serve as reservoirs of prolonged bacterial persistence during Mtb infection

Lymph nodes can contain large numbers of tuberculosis-causing bacteria and serve as long-term reservoirs of bacterial persistence, according to a study published November 1 in the open-access journal PLOS Pathogens by JoAnne Flynn of the University of Pittsburgh School of Medicine, and colleagues.

2 Nov 2018

RTI Surgical enters into definitive agreement to acquire Paradigm Spine

RTI Surgical, Inc., a global surgical implant company, and Paradigm Spine, LLC, a leader in motion preservation and non-fusion spinal implant technology, today announced that they have entered into a definitive agreement whereby RTI will acquire all outstanding equity interest of Paradigm Spine in a cash and stock transaction valued at up to $300 million, consisting of $150 million at closing plus potential future milestone payments.

2 Nov 2018

4TECH successfully completes first two implantations of TriCinch Coil tricuspid valve repair system

4TECH Inc., a leader in the field of transcatheter tricuspid valve repair, initiated its U.S. Early Feasibility Study, following receipt of approval from the U.S. Food and Drug Administration, with the successful first two implantations of the TriCinch Coil System at Piedmont Heart Hospital, Atlanta, Georgia, by Dr. Christopher Meduri, Dr. Vivek Rajagopal and Dr. Mani Vannan.

1 Nov 2018

AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

AstraZeneca will present 20 abstracts including a late-breaking oral presentation on the full results from the Phase III cardiovascular outcomes trial DECLARE -TIMI 58, the broadest SGLT2 inhibitor CVOT conducted to date, as well as new research from the Company's Cardiovascular, Renal & Metabolism therapy area at the American Heart Association Scientific Sessions, November 10-12, 2018, in Chicago, Illinois, USA.

1 Nov 2018

Phase 2 study of ziresovir for treating hospitalized RSV infected infants achieves significant progress

Ark Biosciences, a biotech company developing proprietary therapeutics for viral infection and respiratory diseases, announced today the significant progress in its phase 2 proof-of-concept study of ziresovir in the treatment of hospitalized RSV infected infants.

1 Nov 2018

New drug discovery will increase safety of canine sedation and anesthesia

A drug discovery made at the University of Helsinki's Faculty of Veterinary Medicine will increase the safety of animal sedation and anesthesia. Vatinoxan, the pharmacological molecule discovered in the study, reduced the adverse effects of other drugs on the cardiovascular system of canine patients.

31 Oct 2018

Efficacy News and Research

Study uses gold nanoparticles to remove prostate cancer cells

New multi-allergen test works just as well with dried blood

Scientists grow 3D, beating human heart tissue

Precision medicine: Statistical methods play key role in predicting efficacy of new drugs

Cannabinoids hold promise in treating children with epilepsy

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Researchers develop electroencephalography-based test to objectively measure pain

New study supports use of antibiotic prophylaxis in patients undergoing invasive dental treatment

Experts identify barriers to using stroke-preventing anticoagulants in Canada

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Cooling therapies may offer best protection against adverse effects of taxane-based chemotherapy

Lymph nodes serve as reservoirs of prolonged bacterial persistence during Mtb infection

RTI Surgical enters into definitive agreement to acquire Paradigm Spine

4TECH successfully completes first two implantations of TriCinch Coil tricuspid valve repair system

AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

Phase 2 study of ziresovir for treating hospitalized RSV infected infants achieves significant progress

New drug discovery will increase safety of canine sedation and anesthesia

Researchers examine immune responses to CRISPR-Cas9 gene editing system

Using genome editing to prevent sudden cardiac death

Research reveals high stability of hepatitis B viruses

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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