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Doctors raise concern about heart drug Nesiritide

Doctors raise concern about heart drug. The heart drug Nesiritide (Natrecor) is an FDA-approved drug for the treatment of decompensated heart failure, the most common reason for hospitalization for those over 65 years of age.

22 Mar 2005

Mixed results on the effects of epilepsy drugs taken during pregnancy

New studies show mixed results on the effects of epilepsy drugs taken during pregnancy. With a newer drug, lamotrigine, the risk of birth defects was similar to that in women without epilepsy. But long-time epilepsy drug valproic acid, or sodium valproate, does increase the risk of birth defects.

22 Mar 2005

No serious adverse events found with next-generation smallpox vaccine

Interim data from a phase I/II clinical trial of a next-generation vaccine for smallpox suggest that the vaccine may provide immunity and thus far the trial has been without any serious adverse events.

22 Mar 2005

Federal database used to track trends in cochlear implant complications

Changes in the format of a federal database for mandatory reporting of major and minor complications for medical devices, including cochlear implants, could make it a valuable resource, according to an article in the March issue of Archives of Otolaryngology – Head & Neck Surgery.

22 Mar 2005

Anticonvulsant drug valproate poses greater birth-defect risk than suspected

Use of the anticonvulsant drug valproate during pregnancy may pose a significantly great risk of birth defects than does use of other antiseizure medications.

22 Mar 2005

Support for the use of low-dose aspirin therapy in preventing and treating pre-eclampsia

A new study led by Queen’s University researcher Colin Funk provides indirect support for the use of low-dose aspirin therapy in preventing and treating pre-eclampsia – a pregnancy disorder that is often harmful to both mother and fetus.

22 Mar 2005

Link between high cholesterol and better memory

What's bad for your ticker may be good for your bean, according to a research from a team of scientists at Boston University.

22 Mar 2005

Physical exertion and emotional stress can trigger heart attacks in people with a history of heart disease

Authors Philip Strike and Andrew Steptoe of University College London point out that the triggers for heart attacks may be quite different from the factors that lead to development of coronary heart disease over the long term, such as cigarette smoking, lack of exercise, work stress, social isolation, anxiety and depression.

22 Mar 2005

Depression appears to be a major cause of insomnia in people with HIV

Patients in the last stages of HIV infection with full-blown AIDS and those who have suffered some kind of brain impairment as a result of the disease are also more likely to suffer from insomnia, the reviewers conclude in the current issue of Psychosomatic Medicine.

22 Mar 2005

Patients with chronic fatigue syndrome respond to placebos at a lower rate

Contrary to conventional wisdom, patients with chronic fatigue syndrome respond to placebos at a lower rate than people with many other illnesses, according to the first systematic review of the topic.

22 Mar 2005

Traffic fumes can damage our DNA

A research team in Taiwan studied the effects of exposure to traffic fumes at 20 toll booths located on a motorway 10 km south of Taipei, Taiwan, which has the highest traffic density of any toll station in the country.

21 Mar 2005

The good news and the bad news on epilepsy drugs for pregnant women

Two new studies on the effects of epilepsy drugs taken during pregnancy show mixed results. The risk of birth defects with a newer drug, lamotrigine, was similar to that in women without epilepsy.

21 Mar 2005

Availability of cheap HIV-AIDS drugs threatened by Indian patent law

A controversial Indian patents bill could threaten the lives of millions of people worldwide living with HIV-AIDS and cancer by banning companies from producing cheap copies of brand name drugs.

21 Mar 2005

Compound found in broccoli is a powerful disease fighter

More than 300 scientific studies point to an antioxidant found in broccoli sprouts, sulforaphane glucosinolate (SGS), as a factor in preventing multiple diseases, including several types of cancer, high blood pressure, macular degeneration and stomach ulcers.

21 Mar 2005

New study to evaluate Pegasys and Copegus to treat hepatitis C in liver transplant patients

Roche has initiated a new study to evaluate treatment strategies to reduce post-transplant recurrence of hepatitis C infection with the most prescribed hepatitis C treatment combination in the U.S., Pegasys (peginterferon alfa-2a) and Copegus (ribavirin, USP).

21 Mar 2005

Intervention with once-daily budesonide reduces long-term risk and frequency of severe asthma-related events

New data indicated that earlier intervention with once-daily budesonide, an inhaled corticosteroid delivered by dry powder inhaler to children with mild persistent asthma, significantly reduced the long-term risk and frequency of severe asthma-related events as well as the need for other inhaled medication.

21 Mar 2005

Why respiratory viral infections are often more severe in people with asthma

Lung cells from asthma sufferers fail to invoke critical anti-viral defenses when infected with the common cold virus, according to a study in the March 21 issue of The Journal of Experimental Medicine. These results could help explain why respiratory viral infections are often more severe in people with asthma and how infection can trigger asthma attacks.

21 Mar 2005

Scientists provide insight into the molecular mechanisms behind Listeria monocytogenes

When the bacterium Listeria monocytogenes invades the body, it commandeers its host cell's actin cytoskeleton to invade other cells. In a report published in the Journal of Biological Chemistry, a group of scientists provide insight into the molecular mechanisms behind this infection technique.

21 Mar 2005

Invasive pneumonia and antibiotic resistance decreased after childhood streptococcus pneumoniae vaccine introduced

The problem of increasing antibiotic resistance in cases of Streptococcus pneumoniae, a major cause of pneumonia, meningitis and sepsis, was dramatically reversed following the licensing and use of a new conjugate vaccine for young children in February 2000, according to research conducted at Emory University, the Atlanta Veterans Affairs Medical Center, the Centers for Disease Control and Prevention, and the Georgia Division of Public Health.

21 Mar 2005

Drinking two to three glasses of red wine daily is good for the heart

A review article of the latest studies looking at red wine and cardiovascular health shows drinking two to three glasses of red wine daily is good for the heart, according to a Yale School of Medicine researcher in the Journal of American College of Surgeons.

21 Mar 2005