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SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

New insights into opportunities and challenges of macrogenetics

The burgeoning field of macrogenetics is the focus of a new review published in Nature Reviews Genetics by a global, multidisciplinary team of researchers seeking to better answer fundamental biodiversity questions.

20 Aug 2021

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Proteins are the "tools" of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure.

20 Aug 2021

Study illuminates genetic understanding of aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

20 Aug 2021

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

20 Aug 2021

Genetic nurture has a significant effect on child's educational success, study finds

A child's educational success depends on the genes that they haven't inherited from their parents, as well as the genes they have, according to a new study led by UCL researchers.

19 Aug 2021

Scientists develop a new way to deliver molecular therapies to cells

Researchers from MIT, the McGovern Institute for Brain Research at MIT, the Howard Hughes Medical Institute, and the Broad Institute of MIT and Harvard have developed a new way to deliver molecular therapies to cells.

19 Aug 2021

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

Rare gene variant increases zoonotic H7N9 virus susceptibility in humans

Rare, single-nucleotide variants in the MX1 gene increase human susceptibility to zoonotic H7N9 avian influenza infection, according to a new study.

19 Aug 2021

MD Anderson receives nearly $13 million from CPRIT to support research efforts

The University of Texas MD Anderson Cancer Center has been awarded $12.75 million from the Cancer Prevention and Research Institute of Texas to support basic, clinical, translational and prevention research efforts, including $3 million for a new project to build clinical trial network infrastructure across Texas.

19 Aug 2021

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

New research, available as a preprint on the bioRxiv* server, has focused on the role played by T cell immunity, particularly CD8+ cytotoxic T cells, on preventing lethal infection with SARS-CoV-2 in mice infused with peptide-loaded antigen-presenting dendritic cells (DCs).

19 Aug 2021

Fruit fly provides insight into controlling carbs and fat

Incretins are hormones secreted by intestinal cells that regulate pancreatic insulin and glucagon to control sugar metabolism in mammals.

19 Aug 2021

Remote controlling of CAR-T cells with heat to precisely target tumors

A team of researchers led by bioengineers at the Georgia Institute of Technology is expanding the precision and ability of a revolutionary immunotherapy that is already transforming oncology. CAR T-Cell therapy has been hailed by patients, clinical-researchers, investors, and the media as a viable cure for some cancers.

18 Aug 2021

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

A scientific achievement for researchers at Tel Aviv University: printing an entire active and viable glioblastoma tumor using a 3D printer.

18 Aug 2021

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

A new study has determined the production of the SARS-CoV-2 SP-dependent ORF8.

18 Aug 2021

Why have COVID-19 caseloads been comparatively low in Africa?

A new study has been published in the International Journal of Environmental Research and Public Health that highlights the potential lessons that the world can draw from Africa on assumptions concerning viral pandemics. This is particularly important, given Africa’s long experience with dangerous infectious diseases.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

Scientists propose innovative method to test the effectiveness of coronavirus medicines

South Ural State University scientists have proposed an innovative method for testing the effectiveness of medicines for coronavirus. According to the researchers, it is necessary to focus on the maximum coincidence of the ligand and the receptor. The results of the work have been published in the highly-rated journal "Molecules"(Q1).

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

Research redefines dieting and the culture of weight loss

For decades, there has been an accepted definition of dieting in academia, and in society as a whole. Michael Lowe, PhD, a professor in Drexel University's College of Arts and Sciences, has recently reevaluated the decades of dieting research to redefine the way researchers and the public define – and therefore understand - dieting and the culture of weight loss.

18 Aug 2021

Genetic News and Research

SARS-CoV-2 lambda variant escapes immune response via spike mutations

New insights into opportunities and challenges of macrogenetics

New mouse line reveals the state of protein balance in the mammalian brain for the first time

Study illuminates genetic understanding of aggressive childhood leukemias

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Genetic nurture has a significant effect on child's educational success, study finds

Scientists develop a new way to deliver molecular therapies to cells

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

Rare gene variant increases zoonotic H7N9 virus susceptibility in humans

MD Anderson receives nearly $13 million from CPRIT to support research efforts

Durable highly protective T cell response to AAV-spike vaccine against COVID-19 pneumonia in mice

Fruit fly provides insight into controlling carbs and fat

Remote controlling of CAR-T cells with heat to precisely target tumors

Researchers create the first 3D-bioprinted model of active glioblastoma tumor

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

Why have COVID-19 caseloads been comparatively low in Africa?

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

Scientists propose innovative method to test the effectiveness of coronavirus medicines

New assay using fresh uncultured lung tumor cells could guide personalized treatments

Research redefines dieting and the culture of weight loss

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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