B Cell News and Research

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Scientists develop new receptor “decoy” drug that potently neutralizes SARS-CoV-2 variants

Scientists at Dana-Farber Cancer Institute have developed a drug that potently neutralizes SARS-CoV-2, the COVID-19 coronavirus, and is equally effective against the Omicron variant and every other tested variant.

7 Dec 2022

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

Diarrhea is no longer the killer it was in the mid-20th century, when an estimated 4.5 million children under age 5 died of it every year.

7 Dec 2022

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Wearable technology could improve doctors' ability to administer precise medication doses

For some of the powerful drugs used to fight infection and cancer, there's only a small difference between a healing dose and a dose that's large enough to cause dangerous side effects.

7 Dec 2022

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Researchers reported the immunogenicity, efficacy, and safety of the MVA-BN (modified vaccinia Ankara-Bavarian Nordic)-RSV (respiratory syncytial virus) vaccine against RSV-A (RSV subtype A) Memphis 37b strain in a human challenge trial.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

Researchers attempted to establish an association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load, indicating its ribonucleic acid (RNA) levels, and the presence of infectious virions.

7 Dec 2022

Leica Microsystems and ASI announce partnership to commercialize customizable microscope for advanced users

Single-objective light sheet microscope launched at Cell Bio 2022

From Leica Microsystems GmbH 7 Dec 2022

Metrion Biosciences and The KCNC1 Foundation Collaborate on New Ion Channel Modulators

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From Metrion Biosciences Limited 7 Dec 2022

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Researchers evaluated the immunogenicity, boosting efficacy, and safety of single-dose and two-dose MVA-BN (modified vaccinia Ankara-Bavarian Nordic) vaccinations in comparison to replicating smallpox vaccines.

7 Dec 2022

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Researchers highlighted the significance of air quality in preserving immune health over the human lifespan, especially lung-related immunity, owing to the lungs' continuous exposure to the environment.

7 Dec 2022

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Shenandoah Biotechnology Inc., a FUJIFILM Irvine Scientific company and leading manufacturer of recombinant proteins, today announced it has expanded its CTGrade portfolio of cytokines and growth factors for cell and gene therapies manufactured following cGMP guidelines.

From FUJIFILM Irvine Scientific 7 Dec 2022

Understanding why respiratory infections are more common in the winter

Researchers investigate the role of extracellular vesicles in the innate nasal mucosal response to several respiratory viruses.

6 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Nearly three years into the pandemic, many of us now carry antibodies against the virus - due to an infection or two, a few doses of mRNA vaccine, or a round of monoclonal-antibody treatment.

6 Dec 2022

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

The supply chain that brings meat to market worldwide is highly complex and usually very efficient. But when disruptions in one part of the world can result in transportation delays an ocean and a continent away, meat spoilage becomes a very real risk to food producers, vendors and consumers.

6 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

New study details the neuronal response to excessive aged-related iron accumulation

Iron (Fe) accumulates in the brain cortex with aging. A plethora of studies indicate that progressive iron accumulation in the substantia nigra (SN) in the aged human brain is a major risk factor for Parkinson's disease (PD) and other neurodegenerative diseases, but not everyone.

6 Dec 2022

Innovative precision oncology enabled by micro-organospheres derived from patients

The development of an automatic microfluidics droplet platform to rapidly generate patient-derived models of cancer.

6 Dec 2022

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

University of Central Florida researchers have created unique technology for treating osteoporosis that uses nanobubbles to deliver treatment to targeted areas of a person's body.

6 Dec 2022

B Cell News and Research

Scientists develop new receptor “decoy” drug that potently neutralizes SARS-CoV-2 variants

Vaccination against E. coli could help prevent some forms of childhood malnutrition, stunting

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Wearable technology could improve doctors' ability to administer precise medication doses

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

Leica Microsystems and ASI announce partnership to commercialize customizable microscope for advanced users

Metrion Biosciences and The KCNC1 Foundation Collaborate on New Ion Channel Modulators

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Shenandoah Biotechnology introduces expanded range of CTGrade recombinant proteins manufactured following cGMP practices

Understanding why respiratory infections are more common in the winter

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Paper-based synthetic biosensor could help easily detect toxin putrescine in beef

Research extends the powerful tool of immunotherapy to autoimmune diseases

New study details the neuronal response to excessive aged-related iron accumulation

Innovative precision oncology enabled by micro-organospheres derived from patients

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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