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Investigational Alzheimer's drug reduces molecular markers of the disease

An investigational Alzheimer's drug reduced molecular markers of disease and curbed neurodegeneration in the brain, without demonstrating evidence of cognitive benefit, in a phase 2/3 clinical trial led by researchers at Washington University School of Medicine in St. Louis through its Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU).

21 Jun 2021

University of Louisville receives NIH funding to support research into liver-related illness

The University of Louisville Hepatobiology and Toxicology Center of Biomedical Research Excellence has received $11.3 million in funding from the National Institutes of Health to support its research into liver-related illness for an additional five years.

21 Jun 2021

Women treated with fertility drugs do not have increased breast cancer risk, study shows

Drugs routinely used during fertility treatments to release eggs do not increase the risk of developing breast cancer, new research has shown.

21 Jun 2021

Study reviews natural drug candidates for potential treatment of COVID-19

A recent paper in the Saudi Journal of Biological Sciences seeks to open up new approaches by reviewing a list of compounds derived from plants and other natural sources, which have potential inhibitory activity against the coronavirus.

21 Jun 2021

A World First: sequencing polyclonal antibodies using only proteomics

News-Medical speaks to Bin Ma, President of Rapid Novor, about their latest research that sequenced polyclonal antibodies using only proteomics.

From Rapid Novor Inc 21 Jun 2021

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Recently, researchers discuss their development of cell membrane-based nanoparticles that successfully delivered dexamethasone directly to inflamed lung cells.

21 Jun 2021

Irritable bowel syndrome is linked to bacterial biofilms in the gut

One in six women and one in twelve men in Austria suffers from some form of IBS - therefore around one million people in all. Using currently available techniques, it is only possible to diagnose IBS by a process of elimination.

21 Jun 2021

Effect of national tender system on the costs of biologic and targeted drugs in Norway

At the 2021 EULAR congress, Brkic and colleagues presented data from people with rheumatoid arthritis (RA)treated at Norwegian rheumatology outpatient clinics between 2010 and 2019.

21 Jun 2021

Tiny capsules containing cannabinoids could help treat neurological disorders

A team of researchers led by Curtin University has discovered a new way to improve the absorption rate of medicinal cannabis when taken orally, which could potentially be used to treat neurological disorders such as Alzheimer’s disease, multiple sclerosis and traumatic brain injuries in the future.

21 Jun 2021

Combination of doxycycline and TB drug treatment reduces the size of lung cavities

Globally, an estimated 10 million people develop tuberculosis (TB) each year and the disease remains a leading cause of death from a single infectious agent. Standard short-course anti-TB treatment still requires a regimen of at least six months of antimicrobial drugs, and drug-resistant TB is an increasing public health threat.

21 Jun 2021

Study uncovers new mechanisms underlying lineage plasticity

Cancer cells have an uncanny ability to evolve and adapt to overcome the treatments used against them. While patient survival has been extended by modern drugs that block the production or action of male hormones that fuel prostate cancer -- androgen receptor inhibitors such as enzalutamide, apalutamide, darolutamide, and abiraterone -- eventually these drugs stop working.

21 Jun 2021

Studies provide new evidence of impact of drug price hikes on U.S. patients

Two recent studies led by researchers from the University of Minnesota Medical School add new evidence to the impact of how drug price increases affect U.S. patients and the overall cost of health care.

21 Jun 2021

Novel technique helps evaluate the effect of potential inhibitors on antibiotic-resistant bacteria

Researchers from the Miami University in Ohio have optimized a new technique that will allow scientists to evaluate how potential inhibitors work on antibiotic-resistant bacteria.

21 Jun 2021

Study analyzes uveitis risk after antirheumatic drug withdrawal in children with arthritis

Uveitis is an inflammation of the eye and is a common extra-articular manifestation associated with juvenile idiopathic arthritis (JIA). It can cause vision-threatening complications, and if left uncontrolled may even lead to blindness.

18 Jun 2021

Common blood pressure drug not effective in reducing hospitalization for mildly-ill COVID-19 outpatients

University of Minnesota Medical School researchers determined that the common blood pressure medication, losartan, is not effective in reducing hospitalization for mildly-ill COVID-19 outpatients.

18 Jun 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

A new study, released as a preprint on bioRxiv* server, shows that a combination of the biological interferon-α and the small molecule nafamostat are effective against SARS-CoV-2 infection in vitro, as well as in vivo.

18 Jun 2021

Controlling brain state transitions using a molecule responsive to light

A study led by researchers from IBEC and IDIBAPS achieves, for the first time, the control of brain state transitions using a molecule responsive to light, named PAI.

18 Jun 2021

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

In early January 2021, travelers returning to Tokyo, Japan, from Amazonas, Brazil, were screened for COVID-19 at the airport. A few days later, the National Institute of Infectious Disease of Japan announced that the travelers had returned with a new variant of the SARS-CoV-2 virus.

18 Jun 2021

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

KIYATEC, Inc. announced today the publication of new peer-reviewed data that establishes clinically meaningful prediction of patient-specific responses to standard of care therapy, prior to treatment, in newly diagnosed glioblastoma (GBM) and other high-grade glioma (HGG) patients.

18 Jun 2021

Drugs News and Research

Investigational Alzheimer's drug reduces molecular markers of the disease

University of Louisville receives NIH funding to support research into liver-related illness

Women treated with fertility drugs do not have increased breast cancer risk, study shows

Study reviews natural drug candidates for potential treatment of COVID-19

A World First: sequencing polyclonal antibodies using only proteomics

Targeting lung inflammation with cell membrane-based dexamethasone nanodelivery platform

Irritable bowel syndrome is linked to bacterial biofilms in the gut

Effect of national tender system on the costs of biologic and targeted drugs in Norway

Tiny capsules containing cannabinoids could help treat neurological disorders

Combination of doxycycline and TB drug treatment reduces the size of lung cavities

Study uncovers new mechanisms underlying lineage plasticity

Studies provide new evidence of impact of drug price hikes on U.S. patients

Novel technique helps evaluate the effect of potential inhibitors on antibiotic-resistant bacteria

Study analyzes uveitis risk after antirheumatic drug withdrawal in children with arthritis

Common blood pressure drug not effective in reducing hospitalization for mildly-ill COVID-19 outpatients

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

Combination of interferon-α and nafamostat inhibits SARS-CoV-2 in vivo

Controlling brain state transitions using a molecule responsive to light

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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