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Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Despite tremendous efforts by the global scientific community to curb the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), by developing more efficient testing protocols, therapies, and vaccines at a rapid pace, relatively little is known about the dynamics of SARS-CoV-2 replication within cells.

18 Jun 2021

Recommended treatments can benefit people with lower back pain

Medical guidelines help doctors understand the best way to treat health conditions. Surprisingly, many doctors do not adhere to them, and this is a problem, according to a new study by scientists at University of Utah Health and MDGuidelines.

18 Jun 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

New methods may lead to optimal treatment for lung cancer

Today as they did 100 years ago, doctors diagnose cancer by taking tissue samples from patients, which they usually fix in formalin for microscopic examination.

18 Jun 2021

Researchers propose new strategy for developing drugs based on inhibition of tyrosine kinases

A study performed by researchers at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) in collaboration with Stony Brook University (USA) proposes a new strategy for the development of new drugs based on the inhibition of tyrosine kinase enzymes, molecules that activate and trigger many cellular processes. The results have been published in the Chemistry - A European Journal.

18 Jun 2021

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.

18 Jun 2021

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

New details on transport protein could help develop drugs for neurological diseases

New details on the structure and function of a transport protein could help researchers develop drugs for neurological diseases that are better able to cross the blood-brain barrier.

18 Jun 2021

PET/CT images can be used to measure biomarker levels, predict lung cancer outcomes

Tests that analyze biomarkers are used during cancer management to guide treatment and provide information about patient prognosis.

17 Jun 2021

Inhibiting necroptosis could be a novel approach for treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease, an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

17 Jun 2021

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

RUDN University doctors found alterations in serum amino acid profile in children with attention deficit hyperactivity disorder (ADHD).

17 Jun 2021

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumors have faulty copies of the BRCA cancer genes.

17 Jun 2021

FDA approves antihistamine nasal spray for over-the-counter use

The U.S. Food and Drug Administration today approved a nasal antihistamine for nonprescription use through a process called a partial prescription to nonprescription switch.

17 Jun 2021

Supreme Court declines to overturn ACA — again

The Supreme Court on Thursday turned back its third chance to upend the Affordable Care Act, rejecting a lawsuit filed by a group of Republican state attorneys general claiming that a change made by Congress in 2017 had rendered the entire law unconstitutional.

17 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Device makers have funneled billions to orthopedic surgeons who use their products

Dr. Kingsley R. Chin was little more than a decade out of Harvard Medical School when sales of his spine surgical implants took off.

17 Jun 2021

GW4 takes a 'One Health' strategy to combat antimicrobial resistance

The World Health Organization cites antimicrobial resistance (AMR) as one of the most significant risks facing the world. AMR threatens global health and development as it impacts on human, animal and plant health and also our environment, water safety and food security.

17 Jun 2021

Precision medicine may lead to more effective treatments for ocular conditions

The most practical solution for drug delivery to the eyeball is topical, i.e. eye drops. However, a naturally occurring substance in tears actually can interact with the drug delivery system (DDS), hindering absorption of the drug and preventing it from getting into the cells it needs to target.

17 Jun 2021

Researchers prepare for next coronavirus pandemic

Scientists are already preparing for a possible next coronavirus pandemic to strike, keeping with the seven-year pattern since 2004.

17 Jun 2021

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue.

17 Jun 2021

Drugs News and Research

Study examines SARS-CoV-2 replication in cells using super-resolution microscopy

Recommended treatments can benefit people with lower back pain

Study shows how epigenetic factors modulate the risk of type 1 diabetes

New methods may lead to optimal treatment for lung cancer

Researchers propose new strategy for developing drugs based on inhibition of tyrosine kinases

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

New details on transport protein could help develop drugs for neurological diseases

PET/CT images can be used to measure biomarker levels, predict lung cancer outcomes

Inhibiting necroptosis could be a novel approach for treating COPD

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

FDA approves antihistamine nasal spray for over-the-counter use

Supreme Court declines to overturn ACA — again

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Device makers have funneled billions to orthopedic surgeons who use their products

GW4 takes a 'One Health' strategy to combat antimicrobial resistance

Precision medicine may lead to more effective treatments for ocular conditions

Researchers prepare for next coronavirus pandemic

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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