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Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Researchers at Michigan Medicine have found the livers of patients with a rare disease that affects metabolism have responded positively to leptin therapy.

5 Apr 2017

Study finds cardio-metabolic risk factors even in individuals with normal BMI

A new research study has found that approximately one-third of all individuals with a normal body mass index (BMI) had cardio-metabolic risk factors for heart disease, especially those of South Asian and Hispanic descent.

5 Apr 2017

Method based on genetic information predicts response to drugs in epileptic patients

Researchers affiliated with the University of Campinas in São Paulo State, Brazil, have shown that genetic information can be used to improve early prediction of the response to drugs in patients with mesial temporal lobe epilepsy (MTLE), one of the most severe forms of epilepsy.

5 Apr 2017

New research takes closer look at the brain’s suspension system in TBIs

Traumatic brain injury, or TBI, can be devastating and debilitating. Despite intense interest and years of study, the exact mechanisms linking force and neurological injury remain unclear. Researchers know that the membranes separating the skull from the brain play a key role in absorbing shock and preventing damage caused during a head impact, but the details remain largely mysterious.

5 Apr 2017

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

In an article published recently in Plos One, researchers from INRS-Institut Armand-Frappier Research Centre reported a strategy that could lead to the discovery of new cationic antimicrobial peptides (CAMPs) with greatly enhanced antimicrobial properties.

5 Apr 2017

Low-dose penicillin in early life changes behaviour and balance of gut microbes

In a landmark study, researchers at St. Joseph's Healthcare Hamilton and McMaster University have found that providing clinical (low) doses of penicillin to pregnant mice and their offspring results in long-term behavioural changes.

4 Apr 2017

Low and high birth weights linked to severity of liver disease in children

Researchers at University of California San Diego School of Medicine, with a cohort of clinical collaborators from across the United States, have demonstrated the impact of low and high birth weights in developing Non Alcoholic Fatty Liver Disease (NAFLD), a chronic disease that often leads to a need for organ transplantation.

4 Apr 2017

Vitamin D deficiency linked to early markers of cardiovascular disease in overweight, obese children

In overweight and obese children and adolescents, vitamin D deficiency is associated with early markers of cardiovascular disease, a new study reports. The research results will be presented Sunday, April 2, at ENDO 2017, the annual scientific meeting of the Endocrine Society, in Orlando.

4 Apr 2017

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new research from South Korea suggests.

4 Apr 2017

Simple marker may help predict high or low rate of problems with extended-wear contact lenses

A simple marker on eye examination may help vision care professionals predict which patients will have a higher or lower rate of problems after starting extended-wear contact lenses, reports a study in the April issue of Optometry and Vision Science, the official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.

4 Apr 2017

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California.

4 Apr 2017

OSU scientists find way to fight solid tumors using new cancer-drug delivery system

A new cancer-drug delivery system shows the ability to exploit the oxygen-poor areas of solid tumors that make the growths resistant to standard chemotherapy and radiation treatment.

4 Apr 2017

Researchers discover possible new route to regenerating function lost in diabetes

In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose.

4 Apr 2017

Organoids in cell culture dish offer new insights into development of the brain

A new method could push research into developmental brain disorders an important step forward. This is shown by a recent study at the University of Bonn in which the researchers investigated the development of a rare congenital brain defect.

4 Apr 2017

MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients

The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc’s randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw’s chronic drug delivery system, in Parkinson’s patients.

4 Apr 2017

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.

4 Apr 2017

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

In adolescent girls with polycystic ovary syndrome (PCOS), bringing the amount of abdominal visceral fat and liver fat down to normal restores ovulation, normalizes the symptoms of androgen excess, and may help prevent future subfertility, new research from Spain suggests.

4 Apr 2017

Researchers identify mechanism to recover aging of Progeria patients

DGIST's research team has identified a mechanism that can recover the aging of patients with Hutchinson-Gilford Progeria Syndrome. DGIST announced that the Chair Professor Park SangChul of New Biology and the research team led by Professor Lee YoungSam has discovered a drug that can improve the aging of HGPS patients and identified the mechanism of aging recovery by using the drug.

4 Apr 2017

Paternal diet affects cognitive skills of offspring, mice study shows

The father's lifestyle affects the cognitive skills of his offspring -- at least in mice. Scientists at the German Center for Neurodegenerative Diseases have now shown that if male rodents are fed a diet rich in folic acid, methionine and vitamin B12, their progeny do not perform well in memory tests.

4 Apr 2017

Delaying marriage age of women has positive effects for children, study shows

Delaying the marriage age of young women in parts of the developing world has significant positive effects for their children, a new study shows.

4 Apr 2017

Research News and Research

Liver shows positive response to leptin therapy in patients with partial lipodystrophy, study finds

Study finds cardio-metabolic risk factors even in individuals with normal BMI

Method based on genetic information predicts response to drugs in epileptic patients

New research takes closer look at the brain’s suspension system in TBIs

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

Low-dose penicillin in early life changes behaviour and balance of gut microbes

Low and high birth weights linked to severity of liver disease in children

Vitamin D deficiency linked to early markers of cardiovascular disease in overweight, obese children

Research suggests using combined OGTT and HbA1C tests to screen children at high risk of diabetes

Simple marker may help predict high or low rate of problems with extended-wear contact lenses

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

OSU scientists find way to fight solid tumors using new cancer-drug delivery system

Researchers discover possible new route to regenerating function lost in diabetes

Organoids in cell culture dish offer new insights into development of the brain

MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

Researchers identify mechanism to recover aging of Progeria patients

Paternal diet affects cognitive skills of offspring, mice study shows

Delaying marriage age of women has positive effects for children, study shows

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