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CVRx announces presentation of positive data from Barostim Therapy for Heart Failure clinical trial at HRS 2015

CVRx, Inc., a private medical device company, announced that positive results from the 'Barostim Therapy for Heart Failure' randomized, controlled clinical trial were presented at the 2015 annual Scientific Sessions of the Heart Rhythm Society (HRS) in a Late-Breaking Clinical Trial Session. Results were presented by Dr. Michael Zile from the Medical University of South Carolina.

26 May 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

Aptensio XR once-daily treatment for ADHD to be available in Summer 2015

Today, Rhodes Pharmaceuticals L.P. announced that Aptensio XR, a once-daily central nervous system stimulant indicated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) will be available to patients beginning Summer 2015.

22 May 2015

TGen and Baylor partnership set to increase treatment options for cancer patients

The Translational Genomics Research Institute (TGen) and Baylor Research Institute (BRI) at Dallas today announce an agreement that will focus on accelerating early detection and treatments for patients with a broad range of cancers.

22 May 2015

GHIT Fund expands investments in leishmaniasis, diagnostic tests

The Global Health Innovative Technology Fund, which in the last two years has funded almost $32 million for innovative tools to tackle global infectious diseases, today announced additional investments of nearly $11 million that bring its portfolio to approximately $43 million.

22 May 2015

ICS use may lower risk of mortality from pneumonia and other causes in COPD patients

Treatment of COPD with inhaled corticosteroids (ICS) may decrease the risk of dying from pneumonia and from other causes despite being associated with an increase in the occurrence of pneumonia, according to a new meta-analysis presented at the 2015 American Thoracic Society International Conference.

21 May 2015

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients' own bone marrow to treat multiple myeloma, a cancer of white blood cells.

21 May 2015

Genocea reports positive results from GEN-003 Phase 2 clinical trial for treatment of genital herpes

Genocea Biosciences, Inc., a biopharmaceutical company developing T cell-directed vaccines and immunotherapies, today announced positive top-line data from a Phase 2 dose optimization trial evaluating GEN-003 for the treatment of genital herpes.

21 May 2015

RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

RepliCel Life Sciences Inc., a clinical stage regenerative medicine company focused on the development of autologous cell therapies, announced today an upcoming poster presentation at the International Society for Cellular Therapy on RepliCel's autologous cell treatment for chronic Achilles tendinosis currently in a Phase 1/2 clinical trial.

21 May 2015

Discovery Lab enrolls first patient in phase 2a clinical trial of AEROSURF

Discovery Laboratories, Inc., a specialty biotechnology company focused on developing aerosolized KL4 surfactant therapies for respiratory diseases, today reported that the first patient has been enrolled in the next phase of its phase 2a clinical evaluation of AEROSURF, which is designed to evaluate the safety and tolerability of higher and repeat doses of aerosolized KL4 surfactant administered to premature infants 29 to 34 weeks gestational age (GA) who are receiving nasal continuous positive airway pressure (nCPAP) for respiratory distress syndrome (RDS), compared to infants receiving nCPAP alone.

20 May 2015

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Scientists from the University of Leeds are investigating whether a molecule usually found in moisturisers and skin creams could improve IVF success rates in the UK.

20 May 2015

Similar diabetic macular oedema outcomes with deferred vs prompt laser therapy

Visual acuity outcomes are comparable in diabetic macular oedema patients who receive laser treatment 24 weeks or more after initiation of ranibizumab injections and those for whom laser therapy is initiated concurrently, show the 5-year results of a US study.

19 May 2015

Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on cardio-renal, gastrointestinal, and metabolic diseases, today presented Phase 2b clinical trial results that demonstrated statistically significant and clinically meaningful improvement in IBS-C symptoms for tenapanor-treated patients compared to patients receiving placebo.

19 May 2015

Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

Among patients with acute sciatica caused by a herniated lumbar disk (a condition also known as "acute radiculopathy"), a short course of oral steroids resulted in only modest improvement in function and no significant improvement in pain, according to a study published today in the Journal of the American Medical Association.

19 May 2015

vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

vTv Therapeutics LLC today announced enrollment of the first patients into STEADFAST (Single Trial Evaluating Alzheimer's Disease Following Addition to Symptomatic Therapy), vTv's Phase 3 placebo controlled trial of azeliragon, an oral antagonist of the Receptor for Advanced Glycation Endproducts (RAGE) for treatment of mild Alzheimer's disease.

19 May 2015

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine found that a new non-invasive technology for colon cancer screening is a promising alternative to colonoscopy for African Americans.

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Live, multi-strain probiotic drink may benefit people with ulcerative colitis

People with ulcerative colitis may benefit from taking the live, multi-strain probiotic drink, Symprove, to reduce intestinal inflammation, according to the results of a new study presented today at Digestive Disease Week 2015.

18 May 2015

Investing in new hepatitis C therapies may have significant economic impact

While a new generation of safer, more effective oral medications to treat hepatitis C patients may cost tens of thousands of dollars for a 12-week regiment, investing in these new therapies could generate savings estimated at more than $3.2 billion annually in the U.S. and five European countries, according to a new study (abstract 228) released today at Digestive Disease Week® (DDW) 2015.

18 May 2015

Combined therapy shows promise in cystic fibrosis patients

Treatment with two medications that target the most common genetic cause of cystic fibrosis improves lung function and lowers the rate of pulmonary exacerbations, according to the results from a Phase III international clinical trial published online in the New England Journal of Medicine on May 17, 2015.

17 May 2015

Clinical Trial News and Research

CVRx announces presentation of positive data from Barostim Therapy for Heart Failure clinical trial at HRS 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Aptensio XR once-daily treatment for ADHD to be available in Summer 2015

TGen and Baylor partnership set to increase treatment options for cancer patients

GHIT Fund expands investments in leishmaniasis, diagnostic tests

ICS use may lower risk of mortality from pneumonia and other causes in COPD patients

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

Genocea reports positive results from GEN-003 Phase 2 clinical trial for treatment of genital herpes

RepliCel's autologous cell treatment for Achilles tendinosis to be presented at ISCT 2015

Discovery Lab enrolls first patient in phase 2a clinical trial of AEROSURF

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Similar diabetic macular oedema outcomes with deferred vs prompt laser therapy

Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Short course of oral steroids unlikely to provide much benefit for patients with acute sciatica

vTv Therapeutics enrolls first patients in azeliragon Phase 3 trial for treatment of mild Alzheimer's disease

Study finds new colon cancer screening as promising alternative to colonoscopy for African Americans

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Live, multi-strain probiotic drink may benefit people with ulcerative colitis

Investing in new hepatitis C therapies may have significant economic impact

Combined therapy shows promise in cystic fibrosis patients

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