Clinical Trial News and Research

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Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study finds.

22 Aug 2025

Study finds no increased risk of death associated with higher intake of animal protein

Eating animal-sourced protein foods is not linked to a higher risk of death and may even offer protective benefits against cancer-related mortality, new research finds.

22 Aug 2025

Edible microbeads trap fat to support weight loss

Weight-loss interventions, including gastric bypass surgery and drugs that prevent dietary fat absorption, can be invasive or have negative side effects.

21 Aug 2025

Combination treatment approach shows promise for hard-to-treat triple-negative breast cancer

A new study led by researchers at the Icahn School of Medicine at Mount Sinai has found that adding the targeted therapy everolimus to standard carboplatin chemotherapy extends the time before disease progression in patients with advanced triple-negative breast cancer (TNBC), one of the most aggressive and hard-to-treat forms of breast cancer.

21 Aug 2025

Investigation raises concerns over tooth stem cell banking claims

Parents are spending thousands of pounds to bank stem cells from their children's milk teeth – but the recipient companies' claims about their future medical value are unproven and potentially misleading, reveals an investigation by The BMJ, published today.

21 Aug 2025

Women with Alzheimer's show reduced levels of healthy unsaturated fats

Omega fatty acids could protect against Alzheimer's disease in women, new research has found.

20 Aug 2025

Seven blood metabolites associated with excessive daytime sleepiness

Mass General Brigham researchers identified seven molecules in the blood linked to excessive daytime sleepiness, including factors related to diet and hormones.

20 Aug 2025

International study tests promising vaccine against 21 strains of pneumococcus

A new vaccine for pneumococcal disease will be tested under an international trial aiming to provide greater protection to babies against the common infection that causes pneumonia, sinusitis and meningitis.

19 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

Tenofovir amibufenamide shows efficacy in chronic hepatitis B patients with normal ALT

Chronic hepatitis B virus (HBV)-infected patients may exhibit liver fibrosis and other pathological changes despite normal alanine aminotransferase (ALT).

19 Aug 2025

FAST walk shows promise in improving gait for chronic stroke patients

Stroke remains one of the leading causes of long-term disability worldwide, affecting millions each year.

19 Aug 2025

Community-driven ADHD initiative leads to better outcomes for children

Innovative intervention delivered by trained community health workers – meaning nonclinical personnel with deep knowledge of the community – increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders.

18 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Fasting does not have the same effect on all body types, study suggests

While fasting has become a popular trend, particularly for people who hope to lose weight, new UBC Okanagan research suggests fasting does not have the same effect on all body types.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

New AAV gene therapy reverses age-related macular degeneration

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

18 Aug 2025

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health.

14 Aug 2025

Smartphone app doubles quit rates among low-income smokers

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Clinical Trial News and Research

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Study finds no increased risk of death associated with higher intake of animal protein

Edible microbeads trap fat to support weight loss

Combination treatment approach shows promise for hard-to-treat triple-negative breast cancer

Investigation raises concerns over tooth stem cell banking claims

Women with Alzheimer's show reduced levels of healthy unsaturated fats

Seven blood metabolites associated with excessive daytime sleepiness

International study tests promising vaccine against 21 strains of pneumococcus

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Tenofovir amibufenamide shows efficacy in chronic hepatitis B patients with normal ALT

FAST walk shows promise in improving gait for chronic stroke patients

Community-driven ADHD initiative leads to better outcomes for children

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Fasting does not have the same effect on all body types, study suggests

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

New AAV gene therapy reverses age-related macular degeneration

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

Smartphone app doubles quit rates among low-income smokers

Engineered CD40 antibody shrinks tumors and induces remission

HonorHealth taps longevity authority Nicholas J. Schork to lead new research division

eBook: Using iPSCs models for human disease research and drug discovery eBook

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