Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Study aims to reduce therapy for subsets of patients with intermediate-risk neuroblastoma

Each year, approximately 750 patients are diagnosed with neuroblastoma in North America, the most common form of cancer in infants less than one year old.

8 Aug 2019

Blood clotting proteins in urine act as potent biomarkers for lupus

The team of researchers at the University of Houston found that blood clotting proteins, both the ones that promote blood clotting (prothrombic) and those that disperse them (thrombolytic) are elevated in the urine of patients with lupus nephritis (LN).

7 Aug 2019

FDA approves first therapy for symptomatic tenosynovial giant cell tumor

Today, the U.S. Food and Drug Administration granted approval to Turalio (pexidartinib) capsules for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) associated with severe morbidity or functional limitations and not responsive to improvement with surgery.

3 Aug 2019

Study maps bone marrow niche populations and their differentiation paths

Bone marrow contains biological factories, which pump out billions of new blood cells daily. The non-blood cells that maintain this production also have the potential to produce bone, fat and cartilage.

1 Aug 2019

Preliminary study for detection of pancreatic cancer shows encouraging results

OTraces, Inc., a molecular diagnostics company specializing in early cancer detection, has announced completion of a preliminary study for detection of pancreatic cancer.

1 Aug 2019

First ever American gene-editing treatment using CRISPR for genetic disease

In a pathbreaking experiment, a 34-year-old mother of four from Mississippi is in the limelight for volunteering to be the subject of CRISPR-mediated gene editing in the hope of achieving a cure for the painful sickle cell anemia with which she has suffered all her life.

30 Jul 2019

Scientists discover novel mechanism of action for NK cells in checkpoint inhibitor for cancer

PD-L1 checkpoint inhibitors are a powerful and growing form of immunotherapy used to treat melanoma, kidney cancer, head and neck cancers, Hodgkin's lymphoma and other cancers.

27 Jul 2019

New technology helps develop more personalized treatments for patients with advanced cancers

Being able to identify targets for adoptive cell therapies is one of the first steps in developing personalized treatments for people with hard-to-treat cancers.

22 Jul 2019

Cancer stem cells elude the body's immune cells by deactivating danger detector

Acute myeloid leukemia stem cells elude the body's immune cells by deactivating a danger detector. The underlying mechanisms and the potential new therapeutic approaches that this gives rise to have been detailed in the journal Nature by researchers from the University of Basel and University Hospital Basel in collaboration with colleagues in Germany.

18 Jul 2019

Adding immunotherapy after initial treatment improves survival in metastatic NSCLC patients

Treating metastatic non-small cell lung cancer patients with the immunotherapy drug pembrolizumab after they've completed locally ablative therapy – meaning all known sites of their cancer were either treated with surgery, radiation, or other definitive treatments – almost tripled the median progression-free survival compared to the historical average.

12 Jul 2019

Sports playbook can help generate more accurate prognoses for cancer patients

In this season of global soccer competitions and hotly contested political primaries, bookies and pundits are scouring every evolving scrap of information and sifting through mountains of data in an effort to predict the outcome of the next game or election.

4 Jul 2019

Non-pathogenic bacteria engineered as Trojan Horse to treat tumors from within

The emerging field of synthetic biology-designing new biological components and systems-is revolutionizing medicine.

4 Jul 2019

$FDA grants accelerated approval to new treatment for refractory multiple myeloma$

FDA grants accelerated approval to new treatment for refractory multiple myeloma

Today, the U.S. Food and Drug Administration granted accelerated approval to Xpovio (selinexor) tablets in combination with the corticosteroid dexamethasone for the treatment of adult patients with relapsed refractory multiple myeloma who have received at least four prior therapies and whose disease is resistant to several other forms of treatment, including at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

3 Jul 2019

Children with birth defects have elevated cancer risk, study reveals

Childhood cancer is a rare occurrence in the overall population but may be somewhat more frequent in children born with birth defects.

26 Jun 2019

Expedeon AG launches Lightning-Link Metal Labeling Kits to support single cell analysis

Expedeon AG announced today it has introduced Lightning-Link Metal Labeling Kits for use in multiple immunoassay-based applications to support single cell analysis.

24 Jun 2019

Study identifies proteins that interact with processes regulating gene p53

Scientists at VCU Massey Cancer Center have discovered that the loss of a protein called DBC1 in breast cancer cells leads to the dysregulation of normal anti-cancer functions, contributing to cancer cell growth and resistance to therapies.

24 Jun 2019

Study reveals link between WTC dust and prostate cancer

World Trade Center responders with prostate cancer showed signs that exposure to dust from the World Trade Center site had activated chronic inflammation in their prostates, which may have contributed to their cancer, according to a study by Mount Sinai researchers in Molecular Cancer Research in June.

20 Jun 2019

Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

An investigational drug for the treatment of sickle cell disease is showing early promise in clinical trials for impacting biomarkers of the disease in patients, reported UConn School of Medicine researchers at the European Hematology Association Congress in Amsterdam this week.

20 Jun 2019

Research findings lead to new clinical trial for people with myelofibrosis

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells.

20 Jun 2019