Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

COVID-19 impairs the insulin/IGF signaling pathway

Scientists evaluate the impact of SARS-CoV-2 on the insulin/IGF signaling pathway.

6 Jul 2022

The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Researchers identified SARS-CoV-2 spike surfaces involved in binding to host cell membranes.

6 Jul 2022

Redlined neighborhoods in the 1930s now suffer from higher rates of poor health outcomes

A new study from University Hospitals (UH) Harrington Heart & Vascular Institute further proves that people living in areas that were subjected to housing discrimination decades ago now suffer from higher rates of poor health outcomes, including heart disease, kidney failure and diabetes.

5 Jul 2022

Study: Nearly 80% of people in the U.S. have low to moderate cardiovascular health

About 80% of people in the U.S. have low to moderate cardiovascular health based on the American Heart Association's new Life's Essential 8™ checklist according to a new study published today in Circulation, the Association's flagship, peer-reviewed journal. Life's Essential 8™, also published today in Circulation, details the Association's updated guidance to measure cardiovascular health, adding healthy sleep as essential for ideal heart and brain health.

29 Jun 2022

Sleep turns out to be a significant factor for maintaining cardiovascular health

Sleep duration is now considered an essential component for ideal heart and brain health. Life's Essential 8™ cardiovascular health score replaces Life's Simple 7™, according to a new Presidential Advisory, Life's Essential 8 - Updating and Enhancing the American Heart Association's Construct on Cardiovascular Health, published today in Circulation, the Association's flagship, peer-reviewed journal.

29 Jun 2022

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

The virus that causes COVID-19 undertakes a massive takeover of the body's fat-processing system, creating cellular storehouses of fat that empower the virus to hijack the body's molecular machinery and cause disease.

28 Jun 2022

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth.

27 Jun 2022

Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells.

20 Jun 2022

Machine learning predictive model for screening of LNP-based mRNA vaccines

In this new article publication from Acta Pharmaceutica Sinica B, authors Wei Wang, Shuo Feng, Zhuyifan Ye, Hanlu Gao, Jinzhong Lin and Defang Ouyang from University of Macau, Macau, China and Fudan University, Shanghai, China discuss the prediction of lipid nanoparticles for mRNA vaccines by machine learning algorithms.

18 Jun 2022

Pregnant women with PCOS have higher risk for heart problems during delivery

A common hormone disorder among women of reproductive age has been linked to an increased risk of adverse cardiovascular events and pregnancy outcomes at the time of birth, according to a new study led by Johns Hopkins Medicine researchers.

16 Jun 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Targeting fatty acid metabolism holds promise for Parkinson's disease

The human brain is lipid rich. Lipids and fatty acids contribute to many important cellular processes. Alpha-synuclein - a protein that plays a critical role in Parkinson's disease (PD) - is known to interact with and alter the balance of lipids and fatty acids.

9 Jun 2022

Childhood cancer survivors 80% more likely to be undertreated for cardiovascular risk factors

Adults who survive childhood cancer have a higher risk of cardiovascular disease than the general population, yet they are 80% more likely to be undertreated for several cardiovascular risk factors: hypertension (also called high blood pressure), diabetes and high cholesterol, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

8 Jun 2022

UH expert in lupus reports two new discoveries

Two separate findings by a University of Houston nationally recognized expert in systemic lupus erythematosus (SLE or lupus), a chronic autoimmune disease that affects multiple organs including the kidneys, skin, joints and heart, are being reported in scientific and medical journals.

2 Jun 2022

Membrane lipid stops stress reactions and inhibits cell death

Programmed cell death is an important tool that an organism uses to keep itself healthy. When a cell does not function as it should, various stress reactions are activated. The goal of these reactions is to restore the original cell function.

1 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Consuming about 3 grams a day of omega-3 fatty acids may lead to modest blood pressure reduction

About 3 grams daily of omega-3 fatty acids, consumed in foods or supplements, appears to be the optimal daily dose to help lower blood pressure, according to a research review published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

1 Jun 2022

Research offers entirely new ways to visualize cell membranes

Research from the lab of Matthew Lew at Washington University in St. Louis offers entirely new ways to see the very small.

27 May 2022

Lipids News and Research

Further Reading

COVID-19 impairs the insulin/IGF signaling pathway

The host cell membrane binding surfaces of SARS-CoV-2 spike variants

Redlined neighborhoods in the 1930s now suffer from higher rates of poor health outcomes

Study: Nearly 80% of people in the U.S. have low to moderate cardiovascular health

Sleep turns out to be a significant factor for maintaining cardiovascular health

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Lipid-peptide nanocomplexes offer new mRNA platform

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

Machine learning predictive model for screening of LNP-based mRNA vaccines

Pregnant women with PCOS have higher risk for heart problems during delivery

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

Targeting fatty acid metabolism holds promise for Parkinson's disease

Childhood cancer survivors 80% more likely to be undertreated for cardiovascular risk factors

UH expert in lupus reports two new discoveries

Membrane lipid stops stress reactions and inhibits cell death

Genetically modified herpes virus can be used in the fight against cancer

Consuming about 3 grams a day of omega-3 fatty acids may lead to modest blood pressure reduction

Research offers entirely new ways to visualize cell membranes

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