Pathogen News and Research

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St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year.

31 May 2023

Aggressive lung pathogen may not be prone to person-to-person transmission

A little-known bacterium - a distant cousin of the microbes that cause tuberculosis and leprosy - is emerging as a public health threat capable of causing severe lung infections among vulnerable populations, those with compromised immunity or reduced lung function.

30 May 2023

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Astronauts are affected by various physical and chemical factors during spaceflight, resulting in a series of pathological and physiological changes.

30 May 2023

Researchers find oldest evidence of the plague in Britain to date

Researchers at the Francis Crick Institute have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date, reported in a paper published today in Nature Communications.

30 May 2023

How do the outcomes of viral coinfections vary across host species?

In a recent study published in the journal PLOS Pathogens, researchers investigated the outcomes of coinfections of two viruses — Drosophila C Virus (DCV) and Cricket Paralysis Virus (CrPV) in 25 inbred lines of Drosophila melanogaster and 47 other host species belonging to the Drosophilidae family.

26 May 2023

Antiviral drugs may be a new treatment strategy in the fight against Candida auris

Antiviral drugs can make antifungals work again.

25 May 2023

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The study aimed to predict the future human Buruli ulcer case locations via statistical modelling.

25 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Regular testing and self-isolation can be more effective than closures for combating disease outbreaks

Regular diagnostic testing and self-isolation can be more effective than school and business closures when it comes to combating infectious disease outbreaks such as COVID-19, according to a new study by University of Wyoming researchers.

24 May 2023

Test, isolate, conquer: Study shows testing with self-isolation trumps physical distancing in epidemic control

Researchers discuss the effectiveness of physical distancing and testing with self-isolation as measures to control viral transmission during an epidemic.

23 May 2023

Gut check: Our microbiome's vitamin factory could redefine personal health

Research highlights the crucial role of vitamins in metabolic and regulatory processes. It explores the microbial contribution of essential vitamins, such as vitamin K and B-group vitamins, in the gastrointestinal tract, emphasizing their impact on human health and the gut microbiome.

23 May 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

WHO chief: World must prepare for deadlier outbreak than COVID-19

The world should be prepared to respond to a disease outbreak of "even deadlier potential" than COVID-19, the head of the WHO said after the UN agency launched a global network to monitor disease threats.

23 May 2023

Hydrogel combines nanozymes and probiotics for effective Candida vaginitis treatment

Research introduces FeLab, a responsive hydrogel that combines nanozymes and probiotics for the treatment of Candida vaginitis. FeLab demonstrates effective anti-Candida activity, promotes vaginal mucosa repair, and restores healthy vaginal microbiota, offering a promising therapeutic approach for this condition.

21 May 2023

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

Research highlights the potential of wastewater-based epidemiology as a complementary tool to clinical monitoring for assessing the magnitude of a mpox epidemic. Findings suggest that the presence of mpox DNA in wastewater does not directly correspond to the number of hospitalizations, indicating the underestimation of the epidemic's scale and unidentified cases.

19 May 2023

New technique for early detection of foodborne bacteria

Produce such as lettuce and spinach is routinely tested for foodborne pathogenic bacteria like salmonella, listeria monocytogenes and pathogenic types of E. coli in an effort to protect consumers from getting sick.

18 May 2023

Unraveling how the interplay between Sargassum, plastic marine debris and Vibrio bacteria creates the perfect "pathogen" storm

A new study uncovers how the interplay between Sargassum spp., plastic marine debris and Vibrio bacteria creates the perfect "pathogen" storm that has implications for both marine life and public health. Vibrio bacteria are found in waters around the world and are the dominant cause of death in humans from the marine environment.

18 May 2023

Ticks found to harbor and release prions of chronic wasting disease

Researchers determined whether ticks contain transmission-relevant amounts of chronic wasting disease.

17 May 2023

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Patients with cancer whose immune systems are being supported or rebuilt by bone marrow transplantation should begin receiving vaccines for protection against SARS-CoV-2 three months post-transplant, according to a large, prospective, observational study led collaboratively by the Center for International Blood and Marrow Transplant Research, the Blood & Marrow Transplant Clinical Trials Network and Fred Hutchinson Cancer Center.

16 May 2023

Pathogen News and Research

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Aggressive lung pathogen may not be prone to person-to-person transmission

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Researchers find oldest evidence of the plague in Britain to date

How do the outcomes of viral coinfections vary across host species?

Antiviral drugs may be a new treatment strategy in the fight against Candida auris

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The adaptive immunity of human endemic viruses

Regular testing and self-isolation can be more effective than closures for combating disease outbreaks

Test, isolate, conquer: Study shows testing with self-isolation trumps physical distancing in epidemic control

Gut check: Our microbiome's vitamin factory could redefine personal health

Study findings offer hope for the development of novel treatments for leishmaniasis

WHO chief: World must prepare for deadlier outbreak than COVID-19

Hydrogel combines nanozymes and probiotics for effective Candida vaginitis treatment

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

New technique for early detection of foodborne bacteria

Unraveling how the interplay between Sargassum, plastic marine debris and Vibrio bacteria creates the perfect "pathogen" storm

Ticks found to harbor and release prions of chronic wasting disease

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

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