Statin News and Research

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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.

NTRILIPIX (fenofibric acid) in combo with Rosuvastatin calcium shows improvement on key lipids for cholesterol management

Data from a new study showed that Abbott's TRILIPIX (fenofibric acid) delayed-release capsules in combination with rosuvastatin calcium met all of the study's primary endpoints.

29 Mar 2009

CRESTOR found to reduced CV risk in patients achieving low LDL-C and hsCRP targets in new Jupiter analysis

Results from a new sub-analysis of the JUPITER study show that patients who attained a dual treatment target of LDL-C <70mg/dL and high-sensitivity C-reactive protein (hsCRP) <2mg/L with CRESTOR (rosuvastatin) 20mg achieved a greater reduction in cardiovascular events compared to placebo than those who did not (65% vs 36%, p=0.033) among men and women with low to normal cholesterol levels and elevated hsCRP.

29 Mar 2009

CRESTOR (rosuvastatin) shown to significantly reduce risk of venous thromboembolism

A new analysis from the JUPITER study shows that CRESTOR (rosuvastatin) 20mg significantly cut the risk of venous thromboembolism (VTE) by 43% (p=0.007) compared to placebo among men and women with low to normal cholesterol levels and elevated high-sensitivity C-reactive protein (hsCRP).

29 Mar 2009

Study offers closer look at Takotsubo cardiomyopathy

"Broken heart syndrome" is still a mystery to many in the medical community, but new data from researchers at The Miriam Hospital may shed some light on the clinical characteristics and outcomes of this relatively rare, life-threatening condition.

29 Mar 2009

Levels of PLTP enzyme in blood should be a consideration for potential statin treatment

In a patient study of over 1,000 individuals with coronary artery disease (CAD), researchers have found that high levels of an enzyme called PLTP significantly increased the risk of heart attack in the subset of patients taking statins.

23 Mar 2009

Millions could benefit from statins to prevent heart attacks, strokes

Millions more patients could benefit from taking statins, drugs typically used to prevent heart attacks and strokes, than current prescribing guidelines suggest, Johns Hopkins doctors report in a new study.

19 Mar 2009

Statins reduce odds of an asthma-related hospitalization or ER visit

Results of a new study presented at the 2009 Annual Meeting of the American Academy of Asthma, Allergy and Immunology (AAAAI) show dramatic reductions in emergency room (ER) visits and hospitalizations for asthma patients taking cholesterol-lowering statins in addition to common asthma treatments.

15 Mar 2009

Seniors with 1 type of heart failure may receive little or no benefit from drugs

People over 80 years of age suffering from a certain type of heart failure do not appear to benefit from most commonly prescribed heart medications, according to a study conducted at the Cedars-Sinai Heart Institute and published in the March 15 issue of The American Journal of Cardiology.

12 Mar 2009

Discovery of link between atrial fibrillation and increased risk of death in diabetic patients

Results from a large, international, randomised, controlled trial have shown that there is a strong link between diabetics who have an abnormal heart rhythm (atrial fibrillation) and an increased risk of other heart-related problems and death.

11 Mar 2009

University at Buffalo to receive $4.9 million in stem cell research funds from New York State

The University at Buffalo will receive $4.9 million in funding to conduct research on stem cells, part of a new investment in stem cell research announced yesterday by New York State Governor David A. Paterson.

11 Mar 2009

'Pre-diabetics' face heightened risk of heart disease

The study, published in the Journal of Clinical Endocrinology & Metabolism , was led by Jill P. Crandall, M.D., associate professor of clinical medicine and director of the Diabetes Clinical Trials Unit at Einstein.

3 Mar 2009

Get personal to improve heart health

Scare tactics may not be necessary when trying to get patients at risk of heart disease to change their diet or behaviour, a new study has found.

23 Feb 2009

Statins may lessen brain function

Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function.

23 Feb 2009

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that are independent of cholesterol.

23 Feb 2009

Calculating protein and gene connections in a Parkinson's model

Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli.

22 Feb 2009

Aching back? cholesterol drug Lovastatin might help

Back pain, a hallmark of degenerative disc disease, sends millions of people to their doctor. In fact, more than 80 percent of patients who undergo spine surgery do so because of disc degeneration.

22 Feb 2009

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Using the VAP Cholesterol Test from Atherotech, Inc., University of Maryland researchers have found an association between a rare gene mutation and heart protection.

17 Feb 2009

Continuation of statin treatment associated with lower risk of death

Patients with high cholesterol levels who continually take statins appear to have a lower risk of death over four to five years, regardless of whether they already have diagnosed heart disease, according to a report in the February 9 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

9 Feb 2009

Atorvastatin and lovastatin found to be ineffective for breast cancer prevention

Laboratory work in animals showed limited activity when statins were given to prevent breast cancer, according to a report in the February issue of Cancer Prevention Research , a journal of the American Association for Cancer Research.

8 Feb 2009

Statins may treat cerebral cavernous malformation

In a finding that could save thousands of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol.

27 Jan 2009

Statin News and Research

Further Reading

NTRILIPIX (fenofibric acid) in combo with Rosuvastatin calcium shows improvement on key lipids for cholesterol management

CRESTOR found to reduced CV risk in patients achieving low LDL-C and hsCRP targets in new Jupiter analysis

CRESTOR (rosuvastatin) shown to significantly reduce risk of venous thromboembolism

Study offers closer look at Takotsubo cardiomyopathy

Levels of PLTP enzyme in blood should be a consideration for potential statin treatment

Millions could benefit from statins to prevent heart attacks, strokes

Statins reduce odds of an asthma-related hospitalization or ER visit

Seniors with 1 type of heart failure may receive little or no benefit from drugs

Discovery of link between atrial fibrillation and increased risk of death in diabetic patients

University at Buffalo to receive $4.9 million in stem cell research funds from New York State

'Pre-diabetics' face heightened risk of heart disease

Get personal to improve heart health

Statins may lessen brain function

Statins can stimulate cardiac muscle cell regeneration, improve heart function

Calculating protein and gene connections in a Parkinson's model

Aching back? cholesterol drug Lovastatin might help

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Continuation of statin treatment associated with lower risk of death

Atorvastatin and lovastatin found to be ineffective for breast cancer prevention

Statins may treat cerebral cavernous malformation

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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