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Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually and in trials, which are still at a very preliminary stage, in a review study published in the journal Trends in Pharmacological Sciences.

8 Apr 2026

Study reveals how tau tangles spread from one brain region to another in Alzheimer's

Alzheimer's disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with daily functioning.

8 Apr 2026

New clinical guidelines address blood clot prevention in pediatric patients

The American Society of Hematology (ASH) and the International Society on Thrombosis and Haemostasis (ISTH) released comprehensive clinical practice guidelines on anticoagulant prophylaxis in non-cardiac pediatric patients at risk of venous thromboembolism (VTE).

8 Apr 2026

Clusterin inhibition offers new hope for treating cervical gastric-type adenocarcinoma

Gastric-type adenocarcinoma (GAS) is one of the most aggressive non-human papillomavirus (HPV)-associated cervical adenocarcinomas and remains especially difficult to diagnose and treat.

8 Apr 2026

Future CAR therapy expands beyond T cells to treat diverse diseases

CAR-T therapy has transformed treatment for some blood cancers, with seven FDA-approved products and strong clinical responses in hematologic malignancies.

8 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

Long-term study links common IBS medications to mortality risk

A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)-including antidepressants-may be associated with a small but measurable increase in the risk of death.

8 Apr 2026

New guidelines and follow-up standards improve pulmonary embolism outcomes

Pulmonary embolism, or PE, is a serious and sometimes life-threatening condition that occurs when a blood clot travels to the lungs and blocks blood flow.

8 Apr 2026

Antiviral drugs and shingles vaccines tied to lower dementia risk

New evidence links viral infections to dementia risk, suggesting vaccines and antiviral therapies may offer preventive pathways against cognitive decline.

8 Apr 2026

Self-practice training improves CBT skills and reflective practice

Researchers at The University of Osaka have developed and evaluated a new eight-week training program that enables psychology trainees to effectively CBT by applying its techniques to themselves.

7 Apr 2026

Noninvasive urine test improves prediction of bladder cancer treatment outcomes

Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder cancer (NMIBC), in which the tumors are confined to the inner layers of the bladder.

7 Apr 2026

Study advances safe, reversible male contraceptive without hormones

Cornell University scientists have taken a major step toward developing a safe, reversible, long-acting and 100% effective nonhormonal male contraceptive, considered the holy grail of male contraception.

7 Apr 2026

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

Metformin raised the exercise-linked metabolite Lac-Phe in prostate cancer patients across disease stages and treatment settings, while Lac-Phe itself did not predict anticancer response. Patients in the BIMET-1 metformin arm also showed better weight management during anti-androgen therapy, highlighting a possible metabolic benefit relevant to prostate cancer care.

7 Apr 2026

AI tool predicts Barrett’s esophagus recurrence with high accuracy

A new artificial intelligence (AI)–based tool shows promise for improving surveillance in patients treated with endoscopic eradication therapies for Barrett's esophagus (BE) related dysplasia and early esophageal adenocarcinoma.

7 Apr 2026

Pol theta enzyme identified as key driver of cancer resilience

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

7 Apr 2026

Newly developed smart molecules offer a safer and more precise approach to cancer care

Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care.

7 Apr 2026

Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers

A new research paper was published in Volume 18 of Aging-US on March 26, 2026, titled "Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodeling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF)."

7 Apr 2026

Navigated TMS significantly boosts combat PTSD recovery rates

An advanced version of a procedure using magnetic fields to stimulate brain nerve cells in treating depression was significantly effective for 85% of active military and veterans suffering from combat post-traumatic stress disorder enrolled in a recent study, when added to psychotherapy.

7 Apr 2026

Base editing corrects genetic mutation responsible for severe form of inherited epilepsy

University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the underlying cause of a severe form of epilepsy in lab mice.

7 Apr 2026

Study reveals how Bcl-2 protein blocks cancer cell death

Researchers at Umeå University have contributed new insights into how cancer cells protect themselves from cell death.

7 Apr 2026

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Therapy News and Research

Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

Study reveals how tau tangles spread from one brain region to another in Alzheimer's

New clinical guidelines address blood clot prevention in pediatric patients

Clusterin inhibition offers new hope for treating cervical gastric-type adenocarcinoma

Future CAR therapy expands beyond T cells to treat diverse diseases

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Long-term study links common IBS medications to mortality risk

New guidelines and follow-up standards improve pulmonary embolism outcomes

Antiviral drugs and shingles vaccines tied to lower dementia risk

Self-practice training improves CBT skills and reflective practice

Noninvasive urine test improves prediction of bladder cancer treatment outcomes

Study advances safe, reversible male contraceptive without hormones

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

AI tool predicts Barrett’s esophagus recurrence with high accuracy

Pol theta enzyme identified as key driver of cancer resilience

Newly developed smart molecules offer a safer and more precise approach to cancer care

Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers

Navigated TMS significantly boosts combat PTSD recovery rates

Base editing corrects genetic mutation responsible for severe form of inherited epilepsy

Study reveals how Bcl-2 protein blocks cancer cell death

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