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Liver hormone suppresses alcohol consumption in primates, study shows

A hormone produced by the liver called fibroblast growth factor 21 (FGF21) suppresses alcohol consumption in primates, finds a study published February 1 in the journal Cell Metabolism.

1 Feb 2022

Nanomedicine can be improved with proper and more predictive in vitro assays

Messenger RNA (mRNA) vaccines are a prime example of the promising field of nanomedicine. But progress in the design and application of nanoparticles as efficient delivery vehicles for biopharmaceutics containing nucleic acid or protein drug substances is, unfortunately, remarkably slow.

1 Feb 2022

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Researchers analyze neutralizing antibodies against the SARS-CoV-2 VOCs with the sera of vaccinated individuals infected with the Omicron variant.

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

Study: COVID-19 infections tend to be milder in fully vaccinated patients

The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study published in the journal Radiology.

1 Feb 2022

Researchers discover why patients suffering with hypertension also have diabetes

The long-standing enigma of why so many patients suffering with high blood pressure (known as hypertension) also have diabetes (high blood sugar) has finally been cracked by an international team led by the universities of Bristol, UK, and Auckland, New Zealand.

1 Feb 2022

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exogenous trypsin treatment boosts SARS-CoV-2 infection in Vero E6 cells and promotes viral multiplication in cultured cells.

1 Feb 2022

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

The risk of death for patients with SARS-CoV-2 infection and thoracic cancer is based on seven major determinants, according to research published in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer.

1 Feb 2022

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

A randomized controlled trial assesses the efficacy and safety of high-dose convalescent plasma in the treatment of severe COVID-19.

1 Feb 2022

Researchers develop a single-use sensor strip to detect cerebrospinal fluid leaks

Developing rapid clinical testing for cerebrospinal fluid (CSF) leaks after trauma, surgery, tumors, and other defects are vital, because such leaks can cause life-threatening conditions, such as meningitis and intercranial infection.

1 Feb 2022

New machine-learning model could speed up the process of developing new medicines

Antibodies, small proteins produced by the immune system, can attach to specific parts of a virus to neutralize it.

1 Feb 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Assessing the effects of booster vaccinations against SARS-CoV-2 Omicron variant

In a new study, researchers analyzed the effect of vaccine booster doses against the SARS-CoV-2 Omicron variant.

1 Feb 2022

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

In a new study, a team of researchers assessed the neutralizing activity of XAV-19, a glyco-humanized polyclonal antibody derived from hyperimmunized animal hosts, against the SARS-CoV-2 Omicron variant.

1 Feb 2022

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Protein C News and Research

Liver hormone suppresses alcohol consumption in primates, study shows

Nanomedicine can be improved with proper and more predictive in vitro assays

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Developing post-vaccination SARS-CoV-2 standard reference sera

Study: COVID-19 infections tend to be milder in fully vaccinated patients

Researchers discover why patients suffering with hypertension also have diabetes

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

Researchers develop a single-use sensor strip to detect cerebrospinal fluid leaks

New machine-learning model could speed up the process of developing new medicines

Mutational analysis of SARS-CoV-2 main protease

Assessing the effects of booster vaccinations against SARS-CoV-2 Omicron variant

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Study shows mRNA booster dose eliminates immune escape observed with SARS-CoV-2 Omicron

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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