Clinical Trial News and Research

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New radiation treatment for brain cancer implanted in first human being at CTRC

David Williams is the first human being ever to have a new radiation treatment implanted in the center of his brain tumor.

18 Mar 2015

First clinical trial of new malaria vaccine held in Equatorial Guinea

Equatorial Guinea has held the first clinical trial of a new malaria vaccine known as PfSPZ. Three volunteers participated this month in the trial of the vaccine, which was developed by the American biotechnology company Sanaria. The trial took place at the La Paz Medical Center, the country's premier medical facility, located in Sipopo, just outside the capital.

18 Mar 2015

PVNF gifts $1,250,000 to support Alzheimer's research at UT Southwestern

Presbyterian Village North Foundation has made two gifts totaling $1,250,000 to support Alzheimer's research at UT Southwestern Medical Center.

18 Mar 2015

New research finds old blood just as good as fresh blood

Just like milk and many other foods, blood used for transfusions is perishable. But contrary to popular belief, new research shows that blood stored for three weeks is just as good as fresh blood - findings published today in the New England Journal of Medicine.

18 Mar 2015

Transcatheter MitraClip system safe, effective for valve repair treatment

The commercial track record with transcatheter mitral valve repair, approved for patients at high risk for surgery, compares favorably with pre-approval reports, according to findings from a U.S. registry presented at the American College of Cardiology's 64th Annual Scientific Session.

18 Mar 2015

Novel device improves in-hospital safety outcomes, cognitive scores at discharge

An investigational device that deflects debris away from the brain during transcatheter aortic valve replacement seems to improve in-hospital safety outcomes and cognitive scores at discharge, according to preliminary findings from a small randomized study presented at the American College of Cardiology's 64th Annual Scientific Session.

18 Mar 2015

Baroreflex activation therapy safe, effective for symptomatic advanced heart failure patients

Results of a clinical trial announced today at the American College of Cardiology Annual Scientific Session show a new type of therapy is safe and effective for symptomatic advanced heart failure patients who are already receiving optimum drug and device therapy.

17 Mar 2015

CUMC researchers identify mechanism of kidney transplant tolerance

Columbia University Medical Center researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or eliminating the need for costly and potentially toxic immunosuppressant drugs and improving long-term transplant success.

17 Mar 2015

Patients who receive ablation during mitral valve surgery have less episodes of atrial fibrillation

Patients with atrial fibrillation who received ablation while they were already undergoing surgery to correct a leaky heart valve had fewer episodes of atrial fibrillation a year later compared to patients who had the valve surgery alone, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

17 Mar 2015

Study compares latest drug-coated stents with traditional bypass surgery

Newer drug-coated stents that keep arteries open have similar long-term rates of death compared with traditional bypass surgery for patients with more than one diseased coronary artery.

17 Mar 2015

Raja Atreya wins award for novel diagnostic method to predict treatment outcomes in Crohn's disease

Professor Raja Atreya from Medical Clinic 1 of the Erlangen University Hospital has won the 60,000€ Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers for 2015. With his innovative diagnostic method, physicians can predict the clinical response of an expensive treatment of Crohn's disease which is associated with potential side effects.

17 Mar 2015

New vaccine for post exposure treatment of rabies infection enters human clinical trial

Yisheng Biopharma Co., Ltd., a biopharmaceutical company focusing on the research, development, manufacturing, sales and marketing of vaccine products, announced that a new vaccine for the post exposure treatment of the rabies infection was entering human clinical trial after a six-year long collaboration with a number of research institutes worldwide.

16 Mar 2015

Vaxil Bio's ImMucin receives EMA orphan drug designation for treatment of Multiple Myeloma

Vaxil Bio, a leading developer of immunotherapeutic products to treat cancer and infectious diseases, reports today that its lead drug candidate, ImMucin has received orphan drug designation from the European Medicines Agency of the European Commission for the treatment of Multiple Myeloma (MM), a blood cancer.

16 Mar 2015

AcelRx announces dosing of first patient in pivotal ARX-04 Phase 3 study for treatment of acute pain

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute pain, today reported dosing of the first patient in the pivotal Phase 3 study of ARX-04.

16 Mar 2015

Novimmune tests NI-0501 as first-line treatment for hemophagocytic lymphohistiocytosis

Novimmune SA announces that patients diagnosed with hemophagocytic lymphohistiocytosis (HLH), and who are participating in the company's ongoing clinical trial of its NI-0501 monoclonal antibody, will now be able to be treated with the drug without having to first fail conventional treatments.

16 Mar 2015

Common herpes drug Valacyclovir decreases HIV-1 levels

Case Western Reserve researchers are part of an international team that has discovered that a common herpes drug reduces HIV-1 levels — even when patients do not have herpes.

16 Mar 2015

Results of pacritinib Phase 2 study in myelofibrosis patients published in journal 'Blood'

CTI BioPharma Corp. today announced that results of a Phase 2 study of pacritinib, in patients with myelofibrosis were published in the journal Blood. Pacritinib is a next-generation oral JAK2/FLT3 multikinase inhibitor currently in Phase 3 development in the PERSIST program.

16 Mar 2015

Yale researchers test new device that protects patients' brain during heart-valve replacement procedure

In the first multicenter trial of its kind, Yale researchers tested a new device that lowers the risk of stroke and cognitive decline in patients undergoing heart-valve replacement.

16 Mar 2015

Creatine monohydrate disappoints in Parkinson’s disease

Creatine monohydrate fails to live up to its early promise in patients with Parkinson’s disease, show the results of the Long-term Study 1.

13 Mar 2015

BioSpecifics Technologies provides corporate update, reports Q4 and FY 2014 financial results

BioSpecifics Technologies Corp., a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX (collagenase clostridium histolyticum or CCH) in the U.S. and XIAPEX® in the EU, today announced its financial results for the fourth quarter and full year ended December 31, 2014 and provided a corporate update.

13 Mar 2015

Clinical Trial News and Research

New radiation treatment for brain cancer implanted in first human being at CTRC

First clinical trial of new malaria vaccine held in Equatorial Guinea

PVNF gifts $1,250,000 to support Alzheimer's research at UT Southwestern

New research finds old blood just as good as fresh blood

Transcatheter MitraClip system safe, effective for valve repair treatment

Novel device improves in-hospital safety outcomes, cognitive scores at discharge

Baroreflex activation therapy safe, effective for symptomatic advanced heart failure patients

CUMC researchers identify mechanism of kidney transplant tolerance

Patients who receive ablation during mitral valve surgery have less episodes of atrial fibrillation

Study compares latest drug-coated stents with traditional bypass surgery

Raja Atreya wins award for novel diagnostic method to predict treatment outcomes in Crohn's disease

New vaccine for post exposure treatment of rabies infection enters human clinical trial

Vaxil Bio's ImMucin receives EMA orphan drug designation for treatment of Multiple Myeloma

AcelRx announces dosing of first patient in pivotal ARX-04 Phase 3 study for treatment of acute pain

Novimmune tests NI-0501 as first-line treatment for hemophagocytic lymphohistiocytosis

Common herpes drug Valacyclovir decreases HIV-1 levels

Results of pacritinib Phase 2 study in myelofibrosis patients published in journal 'Blood'

Yale researchers test new device that protects patients' brain during heart-valve replacement procedure

Creatine monohydrate disappoints in Parkinson’s disease

BioSpecifics Technologies provides corporate update, reports Q4 and FY 2014 financial results

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