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Biomolecular researcher provides comprehensive profile of B cells in rheumatoid arthritis

Biomolecular researcher Navin Varadarajan has published in Arthritis & Rheumatology journal a first-of-its-kind study - a comprehensive profile of B cells in rheumatoid arthritis.

12 Apr 2019

Researchers discover unique approach to treat some chronic inflammatory diseases

Inflammation is a balanced physiological response -- the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases.

12 Apr 2019

Aldo-keto reductase family 1 member B10 enzyme found in advanced liver diseases

Nonalcoholic steatohepatitis is associated with liver inflammation in patients with nonalcoholic fatty liver disease, and it can progress to liver fibrosis at an advanced stage, and also to hepatocellular carcinoma and portal hypertension.

12 Apr 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

Increased neutrophil lifespan may contribute to intestinal inflammation in HIV-infected individuals

The increased survival of white blood cells called neutrophils is associated with alterations in the intestinal microbiome of HIV-infected individuals, according to a study published April 11 in the open-access journal PLOS Pathogens by Nichole Klatt of the University of Miami, and colleagues.

11 Apr 2019

Caregiving may not be as bad for the health as previously believed

For decades, articles in research journals and the popular press alike have reported that being a family caregiver takes a toll on a person’s health, boosting levels of inflammation and weakening the function of the immune system.

11 Apr 2019

Study: One in ten childhood asthma cases could be linked to traffic-related air pollution

The first global estimates of their kind suggest that more than one in ten childhood asthma cases could be linked to traffic-related air pollution every year, according to a health impact assessment of children in 194 countries and 125 major cities worldwide, published in The Lancet Planetary Health journal.

11 Apr 2019

Researchers find presence of Aire gene in lymph nodes

The thymus is the organ in which T cells differentiate. T cells express various T cell receptors for reacting with various pathogenic microbes and viruses.

11 Apr 2019

Sexual behavior could affect gut microbiome and immune system

A person's sexual behavior could affect their microbiome and immune system, potentially elevating their risk of HIV infection, according to a new study from researchers at the University of Colorado Anschutz Medical Campus.

10 Apr 2019

Key gene involved in transmission of African sleeping sickness identified

Life scientists from UCLA and the University of Bern have identified a key gene in the transmission of African sleeping sickness -- a severe disease transmitted by the bite of infected tsetse flies, which are common in sub-Saharan Africa.

10 Apr 2019

Study relates DNA methylation levels to obesity

DNA methylation is a mechanism that regulates whether genes are "on" or "off" and is influenced by hereditary and environmental factors, as well as lifestyle and nutritional habits.

10 Apr 2019

Eight-year study identifies potential new way to treat extreme childhood food allergy

An eight-year hunt for the cells that drive the extreme childhood food allergy eosinophilic esophagitis has identified a potential new way to treat the disease while also raising questions about a dietary supplement often taken to reduce bowel inflammation.

9 Apr 2019

New Innovate UK funded project aims to develop biodegradable stents

A £1.1 million project to develop biodegradable stents for patients with severe vascular disease, which affects around one million people in the UK, has started thanks to Innovate UK funding.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019