Tumor News and Research

RSS

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

The presence in advanced breast cancer of mutational signatures characteristic of homologous recombination deficiency (HRD) was associated with improved clinical outcomes to treatment with platinum-based chemotherapy.

19 Dec 2017

Study investigates how brain lesions can contribute to criminal behavior

New research published in the Proceedings of the National Academy of Sciences indicates that lesions to brain areas in individuals exhibiting criminal behavior all fall within a particular brain network involved in moral decision-making.

18 Dec 2017

Study suggests new treatment option for most lethal form of breast cancer

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine.

18 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

HKBU experts develop new generation of smart anti-cancer drug molecules

The toxic nature of chemotherapy poses a great challenge to clinical treatment of cancer. A team of scholars from the School of Chinese Medicine of Hong Kong Baptist University devoted their efforts to the development of a new generation of smart anti-cancer drug molecules.

15 Dec 2017

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Two Johns Hopkins prostate cancer researchers found significant disparities when they submitted identical patient samples to two different commercial liquid biopsy providers.

15 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Active surveillance proposed as first-line approach to manage patients with low-risk PMC of the thyroid

A 10-year study of more than 1,200 patients with low-risk papillary microcarcinoma (PMC) of the thyroid led researchers to conclude that close and continuous monitoring is an acceptable first-line approach to patient management instead of immediate surgery to remove the tumor.

15 Dec 2017

Offering lifesaving treatment for cervical cancer results in a net loss for hospitals

The evidence is clear: Cervical cancer is best treated with brachytherapy, a form of radiation therapy. Yet the use of this potentially lifesaving treatment has been declining, and a new study from the University of Virginia School of Medicine may explain why.

15 Dec 2017

Researchers uncover THOR gene involved in cancer development

It turns out Thor, the Norse god of thunder and the Marvel superhero, has special powers when it comes to cancer too.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Predicting how patients will respond to anti-cancer therapies can be vital in informing clinical decisions and improving treatment outcome.

15 Dec 2017

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

A new study led by scientists at the University of Southampton has found that inherited variation in a particular gene may be to blame for the lower survival rate of patients diagnosed with early-onset breast cancer.

14 Dec 2017

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Cancer molecular testing can drive clinical decision making and help a clinician determine if a patient is a good candidate for a targeted therapeutic drug.

14 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

Radiation therapy can be used to treat patients with life-threatening heart rhythm

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy - aimed directly at the heart - can be used to treat patients with a life-threatening heart rhythm.

14 Dec 2017

Performing surgery on virtual patient could provide valuable insight into consequences

Is surgery the best option or not, in the case of cancer in the head and neck? As the consequences for speaking and swallowing may be severe, some way of predicting these consequences would help in the decision-making.

13 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Tumor News and Research

Mutational patterns could identify breast cancer patients most likely to respond to platinum-based chemotherapy

Study investigates how brain lesions can contribute to criminal behavior

Study suggests new treatment option for most lethal form of breast cancer

Researchers identify novel mechanism that protects from brain tumor

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

HKBU experts develop new generation of smart anti-cancer drug molecules

Prostate cancer researchers find significant disparities between two liquid biopsy providers

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

Active surveillance proposed as first-line approach to manage patients with low-risk PMC of the thyroid

Offering lifesaving treatment for cervical cancer results in a net loss for hospitals

Researchers uncover THOR gene involved in cancer development

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Researchers examine link between tumor mutational burden and response to immune checkpoint therapy

Inherited gene variation may be to blame for poor survival of patients with early-onset breast cancer

Study tests accuracy of laboratory-developed cancer tests and FDA-approved companion diagnostics

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

Radiation therapy can be used to treat patients with life-threatening heart rhythm

Performing surgery on virtual patient could provide valuable insight into consequences

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News