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Researchers use genomic sequencing technique to detect presence of various microbes

About 12,000 bacteria and viruses collected in a sampling from public transit systems and hospitals around the world from 2015 to 2017 had never before been identified, according to a study by the International MetaSUB Consortium, a global effort at tracking microbes that is led by Weill Cornell Medicine investigators.

27 May 2021

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Antibodies aren't the only immune cells needed to fight off COVID-19 - T cells are equally important and can step up to do the job when antibodies are depleted, suggests a new Penn Medicine study of blood cancer patients with COVID-19 published in Nature Medicine.

27 May 2021

Researchers use anesthetics to study reemerging consciousness, cognitive function after anesthesia

Millions of surgical procedures performed each year would not be possible without the aid of general anesthesia, the miraculous medical ability to turn off consciousness in a reversible and controllable way.

27 May 2021

Blood sample analysis can help determine the origin of drugs

The opioid fentanyl is not only used in medical practice as a painkiller, but is also a popular recreational drug. In the United States in particular, fentanyl plays an important role in the opioid crisis that claims many victims every day.

27 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Skeletal muscle is the largest organ in the body that accounts for 30 to 40% of body weight and is responsible for multiple functions such as energy metabolism and heat production.

27 May 2021

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Researchers in the UK, including the University of Oxford and Glasgow, as well as the University of Heidelberg, published their analysis of protein-RNA interactions in SARS-CoV-2 and the subsequent significance in the journal Molecular Cell. This research could help to uncover novel antiviral strategies for COVID-19 due to a broader understanding of how the virus works.

27 May 2021

Light-controlled on/off switch helps control biological clock in cultured cells, explanted tissue

The biological clock is present in almost all cells of an organism. As more and more evidence emerges that clocks in certain organs could be out of sync, there is a need to investigate and reset these clocks locally.

27 May 2021

Could GRP78 be a therapeutic target against COVID-19?

A new study by a team of researchers at the Keck School of Medicine, University of Southern California, USA, reports a potentially important therapeutic target in the form of a molecule called GRP78 that promotes the entry and protein production by many viruses. The team's paper has been published in the Journal of Biological Chemistry.

26 May 2021

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

The National Institute on Aging (NIA), part of the National Institutes of Health, has awarded a $5 million grant to researchers at University of California San Diego School of Medicine to conduct a first-in-human Phase 1 clinical trial of a gene therapy for treating Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

26 May 2021

Novel compound similar to psychedelic drug can reverse effects of stress in mice

A novel compound similar in structure to the psychedelic drug ibogaine, but lacking its toxic and hallucinogenic effects, has been found to rapidly reverse the effects of stress in mice.

26 May 2021

Researchers synthesize potential drugs with anti-cancer effects

New effective compounds, which can be endogenous donors of a signaling molecule - hydrogen sulfide in the body, were synthesized by SUSU scientists. Due to this property, the obtained compounds are potential drugs with a cancer-preventing effect.

26 May 2021

Researchers identify mechanism that may lead to new therapies for strokes, brain injuries

In a surprising discovery, researchers at Massachusetts General Hospital (MGH) identified a mechanism that protects the brain from the effects of hypoxia, a potentially lethal deprivation of oxygen.

26 May 2021

Scientists propose new strategies to find drugs that neutralize critical enzymes

Scientists from the University of Bath explore racemases and propose strategies for finding drugs that target these important enzymes.

26 May 2021

Pain monitoring technology can reduce intraoperative opioid consumption

A new study has shown that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology (Medasense, Israel). The study showed that the NOL monitor is able to detect the effect of dexmedetomidine on the patient's pain response and enable administration of less intraoperative opioids.

26 May 2021

New study may pave way for novel therapeutic strategies for COVID-19

An international and multidisciplinary team led by researchers at the University of Oxford, University of Glasgow, and University of Heidelberg, has uncovered the interactions that SARS-CoV-2 RNA establishes with the host cell, many of which are fundamental for infection.

25 May 2021

New technique using "soft" X-rays offers a simpler way to gain insight into nanocarriers

Before the huge potential of tiny nanocarriers for highly targeted drug delivery and environmental clean-up can be realized, scientists first need to be able to see them.

25 May 2021

Could 6′,6′-difluoro-aristeromycin (DFA) have broad-spectrum antiviral potential against coronaviruses?

Researchers at the Leiden University Medical Center demonstrated that low-micromolar concentrations of 6′,6′-difluoro24 aristeromycin (DFA), an adenosine nucleoside analog, strongly inhibits the replication of Middle East respiratory syndrome coronavirus (MERS-CoV) in a cell-based infection assay.

25 May 2021

Colorado lawmakers wage multifront assault on high drug costs

Tired of waiting for federal action to reduce prescription drug costs, Colorado is acting on its own — even if it must do so with one arm tied behind its back.

25 May 2021

New gel could be used as nasal spray for treating Parkinson's patients

Scientists at the University of York have made significant progress in the development of a nasal spray treatment for patients with Parkinson's disease.

25 May 2021

Drugs News and Research

Researchers use genomic sequencing technique to detect presence of various microbes

Higher CD8 T cells may influence COVID-19 recovery in blood cancer patients

Researchers use anesthetics to study reemerging consciousness, cognitive function after anesthesia

Blood sample analysis can help determine the origin of drugs

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

Oligo DNA improves differentiation of skeletal muscles exacerbated by diabetes

Protein-RNA interactions in SARS-CoV-2-infected cells reveal key regulators of infection

Light-controlled on/off switch helps control biological clock in cultured cells, explanted tissue

Could GRP78 be a therapeutic target against COVID-19?

Researchers to conduct Phase 1 gene therapy trial to treat Alzheimer's disease

Novel compound similar to psychedelic drug can reverse effects of stress in mice

Researchers synthesize potential drugs with anti-cancer effects

Researchers identify mechanism that may lead to new therapies for strokes, brain injuries

Scientists propose new strategies to find drugs that neutralize critical enzymes

Pain monitoring technology can reduce intraoperative opioid consumption

New study may pave way for novel therapeutic strategies for COVID-19

New technique using "soft" X-rays offers a simpler way to gain insight into nanocarriers

Could 6′,6′-difluoro-aristeromycin (DFA) have broad-spectrum antiviral potential against coronaviruses?

Colorado lawmakers wage multifront assault on high drug costs

New gel could be used as nasal spray for treating Parkinson's patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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