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Universal flu vaccine candidate provides protection against severe infection in animal models

Annual flu vaccines protect against severe infection, but they vary in efficacy and may not match the most virulent strains of the season.

23 Aug 2024

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

23 Aug 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

New Mpox strain sparks global health alert

On Wednesday, August 14th, 2024, in response to the active circulation of clade 1 monkeypox virus (MPXV) in Central Africa and the recent expansion of a subtype (1b) thought to be more lethal and transmissible in East Africa, the World Health Organization (WHO) declared a public health emergency of international concern (PHEIC), paving the way for enhanced coordination between regional health systems and the active engagement of stakeholders to tackle this global outbreak. The following day, Thursday August 15, Sweden reported the first positive case of clade 1b mpox on European soil. This led the French government to place the French health system on maximum alert on Friday, August 16, and the French authorities have now begun to re-evaluate the health recommendations established in 2022 during the previous mpox outbreak in preparation for the probable emergence of cases in the country.

23 Aug 2024

Probiotic offers protection against intestinal damage

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium bifidum BB1, enhances intestinal barrier function and protects against penetration of bacteria and various harmful agents in the intestine. The findings, detailed in an article in The American Journal of Pathology, published by Elsevier, can help advance the development of novel, targeted, naturally occurring probiotic therapy for patients with inflammatory bowel disease (IBD) and other inflammatory diseases, such as fatty liver disease or alcoholic liver disease, that are associated with a leaky or disordered intestinal barrier.

23 Aug 2024

Potential antitumoral effects of Manuka honey in breast cancer models

Researchers evaluated the antitumor activity of Manuka honey on human breast cancer cells and its underlying molecular mechanisms in both in vitro and in vivo preclinical models.

22 Aug 2024

Responding to Mpox: Global outbreak, research innovations, and therapeutic strategies

In August 2024, the WHO declared Mpox (formerly known as Monkeypox) a global health emergency due to rising Clade I Mpox cases in Africa and Sweden, highlighting the urgency for coordinated global efforts to monitor and mitigate the spread of the virus.

From Sino Biological Inc. 22 Aug 2024

Advancing cancer therapy with small molecule immune checkpoint inhibitors

Immunotherapy has revolutionized cancer treatment, with immune checkpoint inhibitors (ICIs) playing a pivotal role.

21 Aug 2024

Study links symptomatic chlamydia to higher risk of reproductive complications

The risks of reproductive complications after asymptomatic and symptomatic infections with Chlamydia trachomatis (chlamydia).

21 Aug 2024

Processed and red meat intake associated with higher diabetes risk

Meat consumption, particularly consumption of processed meat and unprocessed red meat, is associated with a higher type 2 diabetes risk, an analysis of data from 1.97 million participants, published today in The Lancet Diabetes and Endocrinology, has found.

20 Aug 2024

Exploring targeted therapies in the complex landscape of multiple myeloma

Multiple myeloma (MM) is a complex hematological malignancy with significant unmet needs. While conventional therapies have significantly improved patient survival, the disease remains incurable.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Study links gut microbe depletion to lifelong respiratory allergies

Researchers at the University of British Columbia have shown for the first time how and why the depletion of microbes in a newborn's gut by antibiotics can lead to lifelong respiratory allergies.

20 Aug 2024

New insights into COVID-19 spike protein offer hope for universal vaccines

A team led by Jose Onuchic at Rice University and Paul Whitford at Northeastern University, both researchers at the National Science Foundation Physics Frontiers Center at the Center for Theoretical Biological Physics (CTBP) at Rice, has made a discovery in the fight against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus responsible for COVID-19.

16 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

Discovery of immune cell regulator could lead to new therapies for inflammatory conditions

The discovery of a new regulator affecting immune cells could lead to new treatments to reduce inflammation in diseases including arthritis and severe COVID 19.

14 Aug 2024

New targets for improved cancer immunotherapy

In the past two decades, immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, showing promising results against various solid tumors. This study reviews recent developments in ICIs, focusing on new targets like T cell immunoreceptors with Ig and ITIM domains (TIGIT), T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), and lymphocyte activation gene-3 (LAG-3). These targets aim to overcome resistance mechanisms limiting the effectiveness of current therapies, such as anti-PD-1 and anti-CTLA-4. By identifying and developing these new ICIs, researchers hope to improve treatment outcomes and provide new therapeutic options for cancer patients.

14 Aug 2024

Antibodies News and Research

Universal flu vaccine candidate provides protection against severe infection in animal models

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

New Mpox strain sparks global health alert

Probiotic offers protection against intestinal damage

Potential antitumoral effects of Manuka honey in breast cancer models

Responding to Mpox: Global outbreak, research innovations, and therapeutic strategies

Advancing cancer therapy with small molecule immune checkpoint inhibitors

Study links symptomatic chlamydia to higher risk of reproductive complications

Processed and red meat intake associated with higher diabetes risk

Exploring targeted therapies in the complex landscape of multiple myeloma

Advances in precision medicine enhance cancer immunotherapy

Study links gut microbe depletion to lifelong respiratory allergies

New insights into COVID-19 spike protein offer hope for universal vaccines

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Discovery of immune cell regulator could lead to new therapies for inflammatory conditions

New targets for improved cancer immunotherapy

Novel vaccination strategy shows promise in boosting immunity and controlling influenza spread in pigs

Nanoparticles offer new hope for treating red meat allergies linked to tick bites

New advances in Hodgkin's lymphoma treatment offer hope for affected individuals

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