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Study reveals osteochondritis risk in children undergoing knee surgery

Growing pains are common in maturing children, but sometimes this growth can be irregular and cause injury. Discoid lateral meniscus (DLM), a misshapen knee cartilage, is one such occurrence that can degenerate into osteochondritis dissecans, a joint disorder where the bone and joint begin to separate from the rest of the bones.

8 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent - a substance that facilitates a reaction - that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Study reveals diverse lengths of luteal phases in healthy women

The current expectation is that every ovulatory menstrual cycle will have a luteal phase (the time from egg released until the next flow) that lasts approximately 14 days.

7 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

Mount Sinai BioDesign expands collaboration with MedTech community to enhance medical innovation

Mount Sinai Health System today announced that Mount Sinai BioDesign, the medical technology incubator of the Health System, has expanded its reach to become a key, effective partner for the broader MedTech community.

3 Oct 2024

Frailty linked to diminished quality of life in cancer and transplant survivors

A new research paper was published on the in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 18 on September 26, 2024, entitled, "Frailty and pre-frailty associated with long-term diminished physical performance and quality of life in breast cancer and hematopoietic cell transplant survivors."

2 Oct 2024

Plant polyphenols: The secret to living longer and healthy aging?

Plant polyphenols show promise in combating aging, supporting mitochondrial health and reducing inflammation, potentially improving quality of life for seniors.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

Nationwide study reveals radon's role in childhood leukemia

A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for mitigation.

30 Sep 2024

Immune modulation as a new strategy to combat periodontal disease

Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research from the University of Pittsburgh.

30 Sep 2024

Extending survival in meningioma patients with innovative radiopharmaceutical therapy

A radiopharmaceutical therapy that has successfully extended progression-free survival for patients with neuroendocrine tumors shows early promise for delivering similar benefits to patients with difficult-to-treat meningioma, a type of brain tumor.

29 Sep 2024

Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million.

27 Sep 2024

Study reveals rising pharmaceutical industry sponsored clinical trials in the U.S.

Researchers at Fred Hutch Cancer Center identified a substantial increase over the past decade in the proportion of patients with cancer in the U.S. who participate in pharmaceutical industry sponsored clinical trials compared to those conducted with federal government support.

27 Sep 2024

Study highlights inequities in emergency care for unintentional ingestions in children

Unintentional injuries like falls, drownings and poisonings are the leading cause of death in patients ages 1-4, and a significant portion of these deaths are linked to unintentional ingestions - such as swallowing a drug or poison.

27 Sep 2024

Insufficient sleep during pregnancy associated with neurodevelopmental risks in offspring

Pregnant women who do not get enough sleep may be at higher risk of having children with neurodevelopmental delays, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

26 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

Nearly half of people older adults plan to get the updated COVID-19 vaccine, poll suggests

The newly updated COVID-19 vaccine just arrived in pharmacies and clinics nationwide, and a new poll suggests nearly half of people age 50 and older plan to get it.

23 Sep 2024

Bone News and Research

Study reveals osteochondritis risk in children undergoing knee surgery

Overcoming CRISPR's side effects for therapeutic applications

Study reveals diverse lengths of luteal phases in healthy women

Epigenetic testing opens new doors for multiple myeloma treatment

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

Mount Sinai BioDesign expands collaboration with MedTech community to enhance medical innovation

Frailty linked to diminished quality of life in cancer and transplant survivors

Plant polyphenols: The secret to living longer and healthy aging?

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Nationwide study reveals radon's role in childhood leukemia

Immune modulation as a new strategy to combat periodontal disease

Extending survival in meningioma patients with innovative radiopharmaceutical therapy

Study highlights potential for targeting macrophages to improve rheumatoid arthritis outcomes

Study reveals rising pharmaceutical industry sponsored clinical trials in the U.S.

Study highlights inequities in emergency care for unintentional ingestions in children

Insufficient sleep during pregnancy associated with neurodevelopmental risks in offspring

Why children with Down’s syndrome are predisposed to developing leukaemia

New drug combo shows promise for deeper remission in chronic leukemia

Key triggers for food allergies in children after organ transplants

Nearly half of people older adults plan to get the updated COVID-19 vaccine, poll suggests

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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