Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Individual clinical judgments needed for prescribing aspirin in primary prevention

The most recent guidelines for primary prevention recommend aspirin use for individuals ages 40 to 70 years who are at higher risk of a first cardiovascular event, but not for those over 70. Yet, people over 70 are at increasingly higher risks of cardiovascular events than those under 70.

17 Feb 2020

Longer sitting times linked to higher heart disease risk among post-menopausal women

Longer sitting times were associated with higher levels of heart disease risk among overweight and obese post-menopausal women overall, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.

17 Feb 2020

Just one minute of exercise per week can provide health benefits to older people

Just one minute of exercise per week is enough to provide health benefits to people over the age of 65, according to new research.

28 Jan 2020

Holistic and data-driven health assessment can help achieve early disease detection

Human Longevity, Inc., an innovator in providing data-driven health intelligence and precision health to physicians and patients, announced today the publication of a ground-breaking study in the journal Proceedings of the National Academy of Sciences.

27 Jan 2020

Abdominal obesity linked to risk of recurrent heart attacks

Heart attack survivors who carry excess fat around their waist are at increased risk of another heart attack, according to research published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

20 Jan 2020

Health benefits of a 'Dry January'

A new year often means a list of resolutions for change, such as abstaining from drinking alcohol, stopping smoking, or living a healthier lifestyle. For one, “Dry January” has become immensely popular because it motivates people to abstain from drinking alcohol for 30 days, at least.

13 Jan 2020

Researchers discover new cellular player involved in obesity

The prevalence of obesity, a disease considered a serious public health problem, is increasing globally. In Portugal, almost half of the population is overweight and close to one million adults suffer from obesity.

11 Jan 2020

High BMI may improve the chance of survival in certain cancers

Above average or high BMI - often linked to cancers, diabetes, cardiovascular and other diseases - may in some cases improve the chance of survival among certain cancers, new research from Flinders University indicates.

26 Dec 2019

Age of onset of obesity linked to higher diabetes risk

A new study shows that the timing of onset of obesity is linked to the risk of type 2 diabetes. The paper, published in the journal Diabetologia, examines how the direction of BMI change, as well as the age when obesity began and the number of years a person is obese (obese-years, the product of degree and duration of obesity) over the period of early adult life are reflected in diabetes risk.

22 Dec 2019

Longevity protein SIRT6 also plays crucial role in burning and regulating liver fat metabolism

Fatty liver, or hepatic steatosis, which develops when the body produces too much fat or doesn't metabolize fat efficiently enough, affects around 25% of the global population. Excess fat is stored in liver cells, where it accumulates and can cause fatty liver and other diseases.

22 Dec 2019

Glutamine could help obese people reduce inflammation of fat tissue

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types.

19 Dec 2019

High-fat meal can silence gut's communication with the body, study shows

A high-fat meal can silence communication between the intestine and the rest of the body, according to a new Duke University study in zebrafish.

17 Dec 2019

Perinatal exposure of rats to flame retardants changes the liver epigenome

Studies have shown that perinatal exposure of rats and mice to common flame retardants found in household items permanently reprograms liver metabolism, often leading later in life to insulin resistance and non-alcoholic fatty liver disease.

13 Dec 2019

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

Exercise improves key measures of cardiovascular health

Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn't improve others like arterial stiffness, an early indicator of cardiovascular risk, investigators report.

9 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

UIC researchers receive $2.9 million to study sleep apnea and chronic kidney disease

University of Illinois at Chicago researchers received $2.9 million from the National Institute of Diabetes and Digestive and Kidney Diseases to study the outcomes of patients with sleep apnea and chronic kidney disease.

3 Dec 2019

Hops compounds may combat metabolic syndrome by changing the gut microbiome

Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research at Oregon State University suggests.

26 Nov 2019

Obese teenagers at risk for brain damage, suggests new study

A new study being presented at the yearly conference of the Radiological Society of North America (RSNA) reports that MRI scanning of the brain shows signs of brain damage in obese adolescents – and that these signs could be the result of brain inflammation.

25 Nov 2019