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Breakthrough research brings new procedure closer to helping patients with blood cancer

A new procedure that can prevent the potentially lethal side effects of stem cell transplants is a step closer to helping more patients with blood cancers after a breakthrough in understanding of the key mechanism that makes it work.

17 Nov 2017

NYU Langone launches new, comprehensive center for facial paralysis

Thousands of New Yorkers every year will suffer some form of facial paralysis, a diagnosis with many causes which can greatly affect a person's appearance and day-to-day functioning.

16 Nov 2017

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

A new study focused on describing genetic variations within a primary tumor, differences between the primary and a metastatic branch of that tumor, and additional diversity found in tumor DNA in the blood stream could help physicians make better treatment choices for patients with gastric and esophageal adenocarcinoma.

15 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Changes in multiple different genes drive world's most deadly forms of lung cancer

A new UC San Francisco–led study challenges the dogma in oncology that most cancers are caused by one dominant "driver" mutation that can be treated in isolation with a single targeted drug. Instead, the new research finds one of the world's most deadly forms of lung cancer is driven by changes in multiple different genes, which appear to work together to drive cancer progression and to allow tumors to evade targeted therapy.

15 Nov 2017

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy, there are no effective treatments or drugs.

14 Nov 2017

Study provides new insights into basis for responsiveness of testicular cancer to chemotherapy

Cornell researchers have taken a major step toward answering a key question in cancer research: Why is testicular cancer so responsive to chemotherapy, even after it metastasizes?

14 Nov 2017

CHLA receives more than $1 million from St. Baldrick's Foundation for cancer research

Three physician-researchers with the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles have been awarded more than $1 million in grants from the St. Baldrick's Foundation, the largest private funder of childhood cancer research.

14 Nov 2017

Dresden researchers develop molecular smoke alert for key human cancer gene

If it burns in a house smoke detectors alert us hence protecting life. A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The alert goes on if the TP53 gene is mutated in cells.

14 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

Novel AR glasses help doctors to locate lymph nodes during surgery

Malignant tumors often form metastases that spread to other parts of the body via the lymphatic system. High surgical skills are required to identify the precise location of the affected lymph nodes, enabling them to be completely removed.

14 Nov 2017

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A.

13 Nov 2017

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London.

13 Nov 2017

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

10 Nov 2017

Russian scientists uncover previously unknown effect of leukemia drug

Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug -- an enzyme called L-asparaginase.

10 Nov 2017

Common genetic fusion event could help identify patients with low-risk prostate cancer

Establishing the way in which a genetic alteration called a TMPRSS2-ERG gene fusion forms in a prostate cancer, rather than the presence of the gene fusion itself, could help identify patients with prostate cancer with a low risk of spreading, which might determine the best course of treatment for the patient.

10 Nov 2017

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

9 Nov 2017

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Tumor News and Research

Breakthrough research brings new procedure closer to helping patients with blood cancer

NYU Langone launches new, comprehensive center for facial paralysis

Genetic diversity of tumor tissues can be barrier to precision medicine in gastric and esophageal cancers

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Changes in multiple different genes drive world's most deadly forms of lung cancer

Synthetic double-stranded RNA may have potential for use as vaccine to prevent liver cancer

Study provides new insights into basis for responsiveness of testicular cancer to chemotherapy

CHLA receives more than $1 million from St. Baldrick's Foundation for cancer research

Dresden researchers develop molecular smoke alert for key human cancer gene

Using AFM to study cancer cells

Novel AR glasses help doctors to locate lymph nodes during surgery

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

Russian scientists uncover previously unknown effect of leukemia drug

Common genetic fusion event could help identify patients with low-risk prostate cancer

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

3D cultured spheroids could drive precision treatment for ovarian cancer

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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