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Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Researchers identify gene variant that protects against severe COVID-19

An international metastudy led by researchers at Karolinska Institutet in Sweden has identified a specific gene variant that protects against severe COVID-19 infection.

13 Jan 2022

Study confirms waning immunity in adolescents following two doses of mRNA COVID-19 vaccines

Researchers test the durability of antibodies produced by a vaccine-induced full-length SARS-CoV-2 spike protein and receptor-binding domain.

13 Jan 2022

Effect of emerging SARS-CoV-2 variants and vaccination status on COVID-19 transmission rates

In a new study, a team of researchers determined the impact of the emerging SARS-CoV-2 variants of concern and vaccination status on the SARS-CoV-2 transmission dynamics.

13 Jan 2022

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

In a new study, researchers used cryogenic electron microscopy (cryo-EM) analysis to capture the open and closed states of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant’s spike protein.

13 Jan 2022

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

In this study, researchers described the effect of significant changes of small RNAs in the post-transcriptional regulatory network.

13 Jan 2022

SARS-CoV-2-specific immune responses elicited by inactivated COVID-19 vaccines

In this study, researchers identified and recruited volunteers who received inactivated COVID-19 vaccines in real-world settings.

13 Jan 2022

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

In the present study, researchers isolated an infectious AY.4.2 strain of COVID-19 from the nasopharyngeal swab of a symptomatic individual from the Paris region. Then, they introduced the AY.4.2 signature mutations - T95I, Y145H, and A222V - in an expression plasmid coding the Delta protein to study the function of the AY.4.2 S protein.

13 Jan 2022

Forecasting seasonal SARS-CoV-2 mutations

In a study published in Science Translational Medicine, researchers have been trying to create a technique to predict which of these mutations will spread.

13 Jan 2022

COVID-19 infection sera analysis against varying antigens of SARS-CoV-2 variants

In a new study, researchers assessed the sera from COVID-19 infected and vaccinated individuals against the receptor-binding domain in the spike protein of the SARS-CoV-2 wildtype virus and its variants.

13 Jan 2022

Nanovaccines and their immunomodulatory effect against human viruses

A review ]presented the primary progress of nanovaccines against the main viral illnesses.

13 Jan 2022

The Native Antigen Company Expands Range of Norovirus-Like Particles

The Native Antigen Company today announced the expansion of its norovirus-like particle range, with the addition of six new reagents.

From The Native Antigen Company 13 Jan 2022

The zoonotic potential of epidemic porcine deltacoronavirus

The present state of knowledge about the genesis, evolution, cross-species transmission, and zoonotic potential of PDCoV is the subject of a review published in the journal Pathogens, which was conducted in a combined effort by researchers from Heilongjiang Bayi Agricultural University and Ohio State University.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood-but only in men-finds a large population study published online in the Journal of Epidemiology & Community Health.

12 Jan 2022

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Researchers examine the effects of disease-modifying therapies implemented for treating multiple sclerosis on the immune response to SARS-CoV-2 infection.

12 Jan 2022

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study.

12 Jan 2022

Protein C News and Research

Virus-like particles as delivery vehicles for gene-editing

Researchers identify gene variant that protects against severe COVID-19

Study confirms waning immunity in adolescents following two doses of mRNA COVID-19 vaccines

Effect of emerging SARS-CoV-2 variants and vaccination status on COVID-19 transmission rates

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

Study finds SARS-CoV-2 infection caused significant changes in the levels of stress associated small RNAs

SARS-CoV-2-specific immune responses elicited by inactivated COVID-19 vaccines

Exploring factors favoring transmission of SARS-CoV-2 Delta sublineage AY.4.2 over the Delta variant

Forecasting seasonal SARS-CoV-2 mutations

COVID-19 infection sera analysis against varying antigens of SARS-CoV-2 variants

Nanovaccines and their immunomodulatory effect against human viruses

The Native Antigen Company Expands Range of Norovirus-Like Particles

The zoonotic potential of epidemic porcine deltacoronavirus

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

Novel insights about dopamine can help find better drugs for Parkinson's patients

Comparing the Moderna and Pfizer-Biontech vaccines against SARS-CoV-2 infection

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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